1,720,963 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Design, synthesis and cytostatic activity of sahaquines
No full textU okviru ovog doktorskog rada dizajnirani su i sintetizirani sahakini, hibridni spojevi u kojima su spojeni dijelovi
molekula antimalarika primakina, odnosno klorokina i citostatika SAHA-e (suberoilanilid hidroksamska kiselina).
Sahakini sadrže tri ključna dijela: kinolinski prsten (dio molekule primakina ili klorokina), središnji dio
(dikarboksilnu kiselinu: jantarnu, fumarnu, glutarnu, adipinsku, tereftalnu) te završni dio s dodatnom
funkcionalnom skupinom (esterskom, karboksilnom, amidnom te O-benzil-, O-metil- ili nesupstituiranom
hidroksamskom kiselinom). Sinteza sahakina polazila je od kinolinskog kraja. Primarna amino skupina primakina,
odnosno analoga klorokina i monoester odgovarajućih dikarboksilnih kiselina povezani su amidnom vezom
pomoću 1-[bis(dimetilamino)metilen]-1H-1,2,3-triazolo[4,5-b]piridinij 3-oksid heksafluorofosfata (HATU) u
prisutnosti N,N-diizopropiletilamina (DIEA) ili preko kiselinskog klorida. Dobiveni su amido-esterski derivati koji
su u sljedećem reakcijskom koraku hidrolizirani u amido-karboksilne kiseline te dalje amidirani s O-metil- ili Obenzilhidroksilaminima,
odnosno halogenanilinima (s atomima fluora/klora ili trifluorometilnom skupinom u meta
ili para položaju) uz HATU i DIEA. Sahakini sa slobodnom hidroksamskom skupinom dobiveni su katalitičkom
hidrogenolizom O-benzilhidroksamskih derivata. Svi sahakini karakterizirani su uobičajenim analitičkim i
spektroskopskim metodama (CHN, IR, 1H NMR, 13C NMR, MS). Antiproliferativno djelovanje sahakina ispitano
je na humanim tumorskim stanicama: adenokarcinoma gušterače (Capan-1), akutne mijeloične leukemije (Hap1),
karcinoma debelog crijeva (HCT-116), karcinoma pluća (NCI-H460), akutne limfoblastičke leukemije (DND-41),
akutne promijelocitne leukemije (HL-60), kronične mijeloične leukemije (K-562), multiplog mijeloma (MM.1S),
ne-Hodkinovog limfoma (Z-138), osteosarkoma (U2OS), hepatocelularnog karcinoma (HepG2), adenokarcinoma
dojke (MCF-7), karcinoma pluća ne-malih stanica (H460) i glioblastoma (U251N). Najaktivniji derivati primakina
bili su sahakini iz podskupine hidroksamskih kiselina te meta-supstituirani derivati halogenanilina s
fumardiamidnom poveznicom. Sahakinu s najjačim citostatskim učinkom, N1-hidroksi-N5-(4-((6-metoksikinolin-8-
il)amino)pentil)-glutaramidu, utvrđen je mehanizam djelovanja. Na staničnom modelu glioblastoma dokazano je da
selektivno inhibira histon-deacetilazu 6, smanjuje ekspresiju matriks-metaloproteaze-2 i receptora za epidermalni
faktor rasta.This doctoral thesis describes the design and synthesis of sahaquines, hybrid molecules in which molecular parts of
antimalarial drug primaquine/chloroquine and cytostatic drug SAHA (suberoylanilide hydroxamic acid) are
merged. Sahaquines constitute of three key parts: quinoline ring (part of primaquine or chloroquine molecule),
linker (dicarboxylic acid: succinic, fumaric, glutaric, adipic, terephthalic) and the terminal part with an additional
functional group (ester, carboxylic, amide, O-benzyl-, O-methyl- or unsubstituted hydroxamic acid). Sahaquine
synthesis starts from the quinoline end. The primary amino group of primaquine/chloroquine is linked with an
appropriate dicarboxylic monoester through an amide bond achieved with 1-[bis(dimethylamino)methylene]-1H-
1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate (HATU) in the presence of N,N-diisopropylethylamine
(DIEA) or by previously activating carboxylic acid with thionyl chloride. Obtained amido-esters were hydrolysed
to afford the corresponding amido-carboxylic acids, which were further coupled with O-benzyl- and Omethylhydroxylamine,
or halogenanlines. HATU/DIEA was used again as the coupling system. Free hydroxamic
acids were obtained by catalytic hydrogenation of O-benzyl derivatives. All new compounds were fully
characterized by conventional spectroscopic and analytical methods (IR, 1H and 13C NMR, MS and elemental
analyses). The cytostatic activity of sahaquines was tested on the following cancer cell lines: pancreatic
adenocarcinoma (Capan-1), chronic myeloid leukemia (Hap1), colorectal carcinoma (HCT-116), lung carcinoma
(NCI-H460), acute lymphoblastic leukemia (DND-41), acute myeloid leukemia (HL-60), chronic myeloid
leukemia (K-562), multiple myeloma (MM.1S), non-Hodgkin lymphoma (Z-138), bone osteosarcoma (U2OS),
hepatocellular carcinoma (HepG2), breast adenocarcinoma (MCF-7) and glioblastoma (U251N). The most active
primaquine derivatives were sahaquines with free hydroxamic acid moiety and diamides with meta-substituted
halogenanilines. The mechanism of action was determined for the most potent sahaquine, namely N1-hydroxy-N5-
(4-((6-methoxyquinolin-8-yl)amino)pentyl)glutaramide. On the glioblastoma cell, it is shown that sahaquine
selectively inhibits histone deacetylase 6, decreases the expression of matrix metalloproteinase-2 and the epidermal
growth factor receptor
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Author Under Sail The Imagination of Jack London, 1893-1902
No full textIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
- …
