1,156 research outputs found

    The estimated frequency of Antiphospholipid antibodies in young adults with cerebrovascular events: A systematic review

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    Background: Around 10% of all thrombotic cerebrovascular events (CVE) occur in young population and in a large proportion of those the trigger remains undetermined. Antiphospholipid antibodies (aPL) are recognised risk factors for ischaemic stroke and recurrent thrombotic events; however, the frequency of aPL in young people with CVE is still an unresolved issue.Objectives: To estimate the frequency of aPL in young adults with CVE and to determine whether aPL-positive young individuals are at greater risk of CVE when compared with individuals without aPL by systematically reviewing the literature.Methods: Medline reports published between 1970 and 2013 investigating the presence of aPL in young patients (<50 years old) with CVE were included. The median frequency for positive aPL, including lupus anticoagulant, anticardiolipin antibodies (aCL) and antibodies against β2Glycoprotein I (anti-β2GPI), was calculated for stroke and transient ischaemic attacks.Findings: This systematic review is based on available data from 5217 patients and controls from 43 studies analysing the frequency of aPL in young patients with CVE. The overall aPL frequency was estimated as 17.4% (range 5%–56%) for any CVE, 17.2% (range 2%–56%) for stroke and 11.7% (range 2%–45%) for transient ischaemic attack (TIA). The presence of aPL increased the risk for CVE by 5.48-fold (95% CI 4.42 to 6.79). Based on available data, the frequency of aPL in young patients with CVE can be estimated at 17%, rising up to 22% for aCL in patients with stroke. The presence of aPL seems to confer a fivefold higher risk for stroke or TIA when compared with controls. However, variability in test reproducibility and cut-off definition still represent an important methodological limitation for the current diagnostic testing for aPL. These observations should be confirmed by appropriately designed population studies

    Fresh fruit and vegetables: a world of multiple interactions : the case of the Buenos Aires Central Wholesale Market (BACWM)

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    This research explores ethnographically the everyday social interactions between the ‘users’ of a particular marketplace, the Buenos Aires Central Wholesale Market (BACWM). The ‘users’ of this marketplace are the social actors who work there everyday, and who bring and buy fresh produce. These ´users´ are the ´makers´ of the BACWM since, through their everyday practices, interactions and interpretations and knowledge, they socially construct this hub of distribution

    A Laboratory for Mathematics

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    Macchine matematiche; dalla storia alla scuola is a book by Maria Grazia Bartolini Bussi and Michela Maschietto that provides a description of the reconstruction of many historical machines for drawing, and their impact on the history of mathematics. Underlying the book’s thesis are ideas about education and developments in neuroscience. Laura Tedeschini Lalli discussed the book and the educational experiments and their goals with author Maria Grazia Bartolini Bussi

    Maria Cristina Arellana, Georgina Estevez, and Laura Tobie

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    This 1965 photograph shows Maria Cristina Arellana of Havana, Cuba, Georgina Estevez and Laura Tobie, both of Caracas, Venezuela in Hubert Hayes Memorial Log Cabin. Founder and director of the Mountain Youth Jamboree, Hubert H. Hayes (1901-1964) auditioned and directed youth to perform in folk dance, music, and folk and ballad singing. The jamboree was held in the Asheville City Auditorium (now known as Thomas Wolfe Auditorium) from 1948 to 1973, and Hayes’ wife, Leona Trantham Hayes (1913-1989) continued to direct the program after his death in 1964. Hubert Hayes was an author, playwright, and alumni of Duke University

    Lethal and sublethal effects of chlorantraniliprole on Spodoptera cosmioides (Lepidoptera: Noctuidae)

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    BACKGROUND: Spodoptera cosmioides (Walker, 1858) population has increased in Bt soybean crops in Argentina. As there are no registered products for its control, the recommended insecticides for S. frugiperda are used. The aim of this study was therefore to determine the lethal concentration (LC) and sublethal effects of chlorantraniliprole on the biological and reproductive functions of S. cosmioides, an emerging soybean pest in Argentina.RESULTS: An ingestion toxicity bioassay showed that chlorantraniliprole was active against larvae of the second instar, and after 48 h exposure LC50 was 0.054 μg/ml H2O. In the study of sublethal effect, chlorantraniliprole induced changes in the life cycle of exposed S. cosmioides, which required more time to complete all stages of development (larval, pupal and adult stages). Pupal weight was also higher in larvae exposed to sublethal concentrations of chlorantraniliprole. Adult fecundity was decreased: the number of eggs laid by each adult female moth, as compared to control females, was two (LC15) and eight (LC30) times smaller.CONCLUSION: These results indicate that chlorantraniliprole has toxicity against S. cosmioides larvae. Sublethal effects on the biological and reproductive performance of this species can help optimize integrated pest management programs.Fil: Lutz, Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Litoral; ArgentinaFil: Bertolaccini, Isabel. Universidad Nacional del Litoral; ArgentinaFil: Scotta, Roberto Ricardo. Universidad Nacional del Litoral; ArgentinaFil: Curis, Maria Cecilia. Universidad Nacional del Litoral; ArgentinaFil: Favaro, María Alejandra. Universidad Nacional del Litoral; ArgentinaFil: Fernandez, Laura Noemí. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Sánchez, Daniel E. Universidad Nacional del Litoral; Argentin

    La transversalidad de la problemática de Género en la docencia y la investigación universitarias: Una experiencia realizada desde la cátedra de Sociología Sistemática de la Facultad de Ciencia Política y RR. II. y el Centro de Investigaciones y Estudios del Trabajo (CIET) - UNR

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    Este artículo narra una experiencia de imbricación entre docencia, investigación y extensión desde una perspectiva de género. La cátedra de Sociología Sistemática corresponde al segundo año de las carreras de Ciencia Política y de Relaciones Internacionales de la facultad de Ciencia Política y RRII de la Universidad Nacional de Rosario y fue la primera asignatura en ser transversalizada por la problemática de género en esta universidad.Por otro lado, en el plano de la investigación y vinculación con el medio, el Centro de Investigaciones y Estudios del Trabajo (CIET) de la Facultad de Ciencia Política y RR. II. de la UNR, que fue creado en el año 1996 y presenta un largo recorrido en el abordaje de problemáticas del mundo del trabajo, está compuesto, entre una de sus áreas más importantes, por el Área de Género que tiene como finalidad la formación, divulgación e investigación de la perspectiva de género en los estudios del trabajo.En este artículo, hemos dividido el desarrollo de esta experiencia en tres apartados. En primer lugar, explicaremos cómo se ha dado el trabajo en la cátedra para la incorporaciónde la problemática de género. En segundo lugar, expondremos la fundamentación y los objetivos de los proyectos de investigación relacionados con esta experiencia, haciendohincapié en la relación investigación-docencia. En el tercer y último apartado daremos cuenta de las actividades concretas que realizamos desde la cátedra y en el marco institucional del CIET, relacionando los procesos de aprendizaje de lxs alumnxs en vinculación con el territorio.Fil: Dicapua, Maria de Los Angeles. Universidad Nacional de Rosario. Facultad de Ciencia Política y Relaciones Internacionales; ArgentinaFil: Teglia Palermo, Paulina. Universidad Nacional de Rosario. Facultad de Ciencia Política y Relaciones Internacionales; ArgentinaFil: Bertolaccini, Luciana María. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario; Argentina. Universidad Nacional de Rosario. Facultad de Ciencia Política y Relaciones Internacionales; Argentin

    L'unificazione del mondo. Alexandre Kojève e lo Stato universale e omogeneo

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    The Author reconstructs the genesis and the later developments of the concepts of the «universal and homogeneous State» in Kojève’s writings. From the lectures on Hegel to the Phenomenology of Right and the correspondence with Leo Strauss and Carl Schmitt, the paper analyses Kojève’s thought on the universal and homogeneous State as the political form of the post-historical age. In the last part, the Author reflects on Kojève’s vision of the political form of Europe

    Immagini della libertà

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    This essay reconstructs several images of political concept of freedom in the modern and contemporary tradition. In the first part the Author traces the genealogy of modern political concept of freedom that produces the achievement of sovereignty and the individual rights in the age of revolutions. This political and historical process shows an image of freedom as property of the modern subject which is free because safe, autonomous and independent. In the second part, the Author introduces a different imagine of freedom in accord with the arendtian position of What is freedom? So political freedom can be sketched as an action, a new beginning, an unexpected event; and thus, this different image of freedom is showed as a possible way out from our age of crisis

    Alla ricerca dell'utopia?

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    The Author traces the modern history of political concept of utopia from the publication of More’ Utopia. The historic-philosophical analysis shows that the opposition utopia vs realism and its transformations was (and still is now) central to develop the dialectic between reality and imagination, which is one of the axis of the western political Modernity. But, the epistemic and socio-political crisis of the XXth Century reveals the aporia and contradictions within this dialectic. However, in front of fear and angst ruling our present, the Author shows that a possible way out of our crisis could be in starting up again this dialectic along giving birth to new forms of our political coexistence

    Rileggere la paura oggi. Volti e forme di una passione lungo i secoli

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    Fear is a passion that deeply characterizes the human nature and it has been a pivotal analytical topic of the Western Thought. The author, through the discussion of two recent books of Marco Filoni (Anatomia di un assedio, Milano 2019) and Martha Nussbaum (The monarchy of fear, It. trans. Bologna 2020) reflects on the political utilization of Fear in light of the actual transformations. Fear is considered crucial for understanding political modernity, while its reappearance in democratic societies is highly challenging and jeopardizes their capacity of cohesion and political order. By discussing the theoretical theses of Filoni and Nussbaum, the author points out the need to go beyond the politics of Fear by reactivating different political passions like Hope
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