1,721,120 research outputs found
Uterine tumors resembling ovarian sex cord tumors: a case report of conservative management in young women.
No full textInt J Gynecol Cancer. 2009 May;19(4):808-10.
Uterine tumors resembling ovarian sex cord tumors: a case report of conservative management in young women.
Berretta R, Patrelli TS, Fadda GM, Merisio C, Gramellini D, Nardelli GB.
SourceDepartment of Obstetrics and Gynecology, University of Parma, Parma, Italy. [email protected]
Abstract
Uterine tumors resembling ovarian sex cord tumors (UTROSCT) are distinguished into two separate groups: endometrial stromal tumors with sex cord-like elements (Group I), which have an unfavorable prognosis; and UTROSCT proper (group II), with more than 40% sex cord-like differentiation and less endometrial component, which are biologically less aggressive than the tumors of the other group. We report the case of a young woman with UTROSCT treated by minimally invasive hysteroscopic surgery. This is one of the few cases reported in the literature that have been managed conservatively
Isolated ovarian relapse of pre-b acute lymphoblastic leukemia.
No full textJ Pediatr Adolesc Gynecol. 2009 Aug;22(4):e65-8. Epub 2009 Jun 2.
Isolated ovarian relapse of pre-B acute lymphoblastic leukemia: a case report.
Berretta R, Barone A, Rolla M, Bertolini P, Nardelli GB.
SourceDepartment of Obstetrics and Gynecology, University of Parma, Parma via gramsci 14 -43100, Italy. [email protected]
Abstract
BACKGROUND: Acute lymphoblastic leukemia is a malignant disease of the bone marrow in which early lymphoid precursors proliferate and replace normal marrow hematopoietic cells, resulting in a marked decrease in the production of normal blood cells.
CASE REPORT: We report a case of isolated ovarian relapse 7 years after the primary diagnosis in a patient, who was seemingly in clinical remission following unilateral ovariectomy and second-line chemotherapy.
CONCLUSION: In contrast to testicular relapse, ovarian relapses in acute lymphoblastic leukemia are rarely reported. Surgical removal of the mass followed by chemotherapy is the therapeutic standard
Laparoscopic management of gynaecological cancer in pregnancy.
No full textJ Obstet Gynaecol. 2010 Apr;30(3):319-21.
Laparoscopic management of gynaecological cancer in pregnancy.
Berretta R, Rolla M, Ceccaroni M, Benassi G, Modena AB, Nardelli GB.
SourceDepartment of Obstetrics and Gynecology, University of Parma, Parma, Italy. [email protected]
In pregnant women, the incidence of cervical cancer is estimated at around 1 in 10,000 (Amant et al. 2009), while the rate of adnexal masses varies between 2% and 4% (Amant et al. 2009). Approximately 6% of all operated adnexal masses are malignant and the incidence of ovarian cancer during gestation fluctuates from 1 in 10,000 to 1 in 100,000. The purpose of this study was to report our experience with laparoscopy in pregnant women for the management of gynaecological cancer
Incidence of port-site metastases after laparoscopic pure management of borderline ovarian tumors : a series of 22 patients
No full textEur J Gynaecol Oncol. 2009;30(3):300-2.
Incidence of port-site metastasis after laparoscopic management of borderline ovarian tumors: a series of 22 patients.
Berretta R, Rolla M, Patrelli TS, Gramellini D, Fadda GM, Nardelli GB.
SourceDepartment of Gynecology, Obstetrics and Neonatology, University of Parma, Parma, Italy. [email protected]
Abstract
PURPOSE: The aim of this work was to evaluate the incidence of port-site metastasis in patients undergoing laparoscopy for borderline ovarian carcinoma (BOT).
METHODS: Twenty-two patients who underwent laparoscopy from 2004 to 2008 for BOT were evaluated retrospectively.
RESULTS: In 15 patients an ultraconservative procedure with enucleation of the annexal neoplasia was carried out, while in five (23%) unilateral salpingo-oophorectomy was performed and in two cases (9%) bilateral salpingo-oophorectomy was done.
CONCLUSION: The literature data report few cases of port-site metastasis in BOT patients. Residual cutaneous metastases have been reported to occur within 12 months from the first surgery, generally in association with serous histology. In our analysis, we found 17 out of 22 cases of serous BOT, three mucinous and two endometriod. In no case was cutaneous metastasis revealed after an average of 30 months of follow-up
Rhabdomyoma of the vagina.
No full textAnn Pathol. 2012 Feb;32(1):53-7. Epub 2012 Jan 14.
[Rhabdomyoma of the vagina. Case report and short literature review].
Patrelli TS, Franchi L, Gizzo S, Kiener A, Berretta R, Piantelli G, Caruana P, Battista Nardelli G, Bacchi Modena A.
SourceUniversità degli Studi di Parma, Clinica Ginecologica ed Ostetrica, Parma, Italie.
Abstract
The differential diagnosis of vaginal polypoid masses should take rhabdomyoma into consideration even it is an extremely rare tumor. The present report describes a vaginal cystic mass located in the anterior wall of an asymptomatic, 38-year-old, Caucasian, nulliparous woman. Local excision and subsequent pathological examination were performed. The final diagnosis was vaginal rhabdomyoma. The literature is reviewed and differential diagnosis are discussed
Squamotransitional cell carcinoma of the vagina: diagnosis and clinical management: a literature review starting from a rare case report.
No full textPathol Oncol Res. 2011 Mar;17(1):149-53. Epub 2010 May 30.
Squamotransitional cell carcinoma of the vagina: diagnosis and clinical management: a literature review starting from a rare case report.
Patrelli TS, Silini EM, Berretta R, Thai E, Gizzo S, Bacchi Modena A, Nardelli GB.
SourceOb/Gyn Clinic, University of Parma, Parma, Italy. [email protected]
Abstract
Primary squamotransitional cell carcinoma (STCC) is rare squamous cell tumor variant resembling transitional cell carcinoma (TCC) of the urinary tract. STCC occurs rarely in the vagina and its clinical and pathological correlates are poorly known. We report a unique case of a 66-year-old Italian woman with STCC of the vagina. A biopsy of the tumor was performed. The tumor qualified as a STCC. Following biopsy, the patient underwent radical hysterectomy (Piver's III-type) with bilateral salpingo-oophorectomy, upper colpectomy, appendicectomy, peritoneal cytology, and lymphadenectomy. The patient is now healthy without evidence of recurrence at 30 months after surgery. Pathologically, cytoarchitectural characteristics distinguish this histotype (STCC) from conventional squamous cell carcinoma of the genital tract. The cytokeratin staining pattern (CK7 positive and CK20 negative), the p63 expression and the positivity for p16ink4a and high-risk HPV are the main elements of differential diagnosis. We suggest that STCC of the vagina should be treated by radical surgery, possibly followed by adjuvant therapy based on staging results and should receive a long-term follow-up
Pelvic lymphadenectomy in endometrial cancer: our current experience.
No full textEur J Gynaecol Oncol. 2009;30(5):536-8.
Pelvic lymphadenectomy in endometrial cancer: our current experience.
Patrelli TS, Berretta R, Rolla M, Vandi F, Capobianco G, Gramellini D, Bacchi Modena A, Nardelli GB.
SourceDepartment of Gynecology, Obstetrics and Neonatology, University of Parma, Italy. [email protected]
Abstract
OBJECTIVE: Lymph node involvement is the single most important factor in the prognosis of endometrial cancer, because it is predictive of locoregional and distant metastases. The purpose of our study was to determine whether lymphadenectomy is useful in the surgical staging of endometrial cancer and if it may help establish a more accurate prognosis and reduce the need for postoperative therapy in patients without surgical complications.
STUDY DESIGN: We conducted a retrospective study on 55 patients with diagnosis of endometrial cancer.
RESULTS: Surgical staging of patients undergoing pelvic lymphadenectomy (47/55) showed that 59.6% of cases (n = 28) had Stage I cancer (IA in 4, IB in 16, IC in 8), 17.02% (n = 8) Stage II (IIA in 3, IIB in 5), 21.2% (n = 10) Stage III (IIIB in 5, IIIC in 5), and 2.1% (n = 1) Stage IVA. In the remaining eight patients with a very high anesthesiologic risk (ASA 4), surgical staging was incomplete because they underwent only node palpation.
CONCLUSION: In conclusion, as we wait for the sentinel lymph node technique to demonstrate satisfactory results and be standardized also for endometrial cancer, we believe that surgical lymph node dissection plays a crucial role in debulking this type of cancer. When performed by a good surgical oncology team, it does not entail a significantly increased operative risk
Randomised prospective study of abdominal wall closure in patients with gynaecological cancer.
No full textAust N Z J Obstet Gynaecol. 2010 Aug;50(4):391-6.
Randomised prospective study of abdominal wall closure in patients with gynaecological cancer.
Berretta R, Rolla M, Patrelli TS, Piantelli G, Merisio C, Melpignano M, Nardelli GB, Modena AB.
SourceDepartment of Obstetrics and Gynecology, University of Parma, Italy. [email protected]
Abstract
BACKGROUND: Median laparotomy is the most common approach to the abdominopelvic cavity in patients with gynaecological tumours.
AIMS: The primary endpoint of the study was to evaluate the onset of incisional hernia. The secondary endpoint was to evaluate the onset of infection, wound dehiscence, wound infection, and scar pain during the post-operative period.
METHODS: A total of 191 patients were eligible for the study. They were divided into three groups. Group A underwent en bloc closure of the peritoneum and fascia with Premilene suture, Group B en bloc closure of the peritoneum and fascia with Polydioxanone suture, and Group C separate closure of the peritoneum and fascia with single stitches of Ethibond suture. Statistical analysis was performed using the Statistical Software Package for Social Sciences 12.0.
RESULTS: Group A and Group B comprised 63 patients, and Group C included 65 patients. The three groups proved homogeneous on statistical analysis (P > 0.05). The statistical analysis did not reveal significant differences between the different suture types and techniques with respect to the incidence of incisional hernia (P > 0.05).
CONCLUSION: In our study, the incidence of incisional hernia was 8%. Randomised patients were homogeneous for sample size and risk factors. No significant differences were found between suture types or techniques. Currently, there is no suture material or technique that can be considered superior to others. When possible, we believe that the best way to prevent incisional hernia is to preserve the integrity of the abdominal wall using minimally invasive techniques
Extragenital Müllerian adenosarcoma with pouch of Douglas location.
No full textBMC Cancer. 2011 May 15;11:171.
Extragenital Müllerian adenosarcoma with pouch of Douglas location.
Patrelli TS, Silini EM, Gizzo S, Berretta R, Franchi L, Thai E, Lukanovic A, Nardelli GB, Modena AB.
SourceDepartment of Obstetrics, Gynecological and Perinatology Sciences, University of Parma, Italy. [email protected]
Abstract
BACKGROUND: Of all female genital tract tumors, 1-3% are stromal malignancies. In 8-10% of cases, these are represented by Müllerian adenosarcoma an extremely rare tumor characterized by a stromal component of usually low-grade malignancy and by a benign glandular epithelial component. Variant that arises in the pouch of Douglas is scarcely mentioned in the medical literature.
CASE PRESENTATION: A 49-year-old para-0 woman, was seen at our OB/GYN-UNIT because she complained vaguely of pelvic pain. She had a mass of undefined nature in the pouch of Douglas. A simple excision of the mass showed low-grade Müllerian adenosarcoma with areas of stromal overgrowth. One and a half year after surgery, at another hospital, a mass was detected in the patient's posterior vaginal fornix and removed surgically. Six months later she came back to our observation with vaginal bleeding and mass in the vaginal fornix. We performed radical surgery. The pathological examination showed recurrent adenosarcoma. Surgical treatment was supplemented by radiation therapy.
CONCLUSIONS: The case of Müllerian adenosarcoma reported here is the third known so far in the literature that was located in the pouch of Douglas. To date, only two other such cases have been reported, including one resulting from neoplastic degeneration of an endometriotic cyst
- …
