132,806 research outputs found

    How much can the orientation of G's eigenvectors tell us about genetic constraints?

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    A key goal in evolutionary quantitative genetics is to understand how evolutionary trajectories are constrained by pleiotropic coupling among multiple traits. Because studying pleiotropic constraints directly at the molecular genetic level remains very difficult, several analytical approaches attempt to draw conclusions about constraints by relating the orientation of the eigenvectors of the traits' (co)variance matrix to vectors of multivariate selection. On the basis of explicit models of genetic architecture, I here argue that the value of such approaches is greatly overestimated. The reason is that eigenvector orientation can be highly unstable and lack a biologically meaningful relationship with the underlying traits' genetic architecture. Genetic constraints are more profitably explored through experimental approaches avoiding the mathematical abstraction inherent in eigenanalysis

    Shape-D - Stärkung der Handlungskompetenzen Pflegender im Umgang mit Menschen mit Demenz

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    Dem Projekt Shape-D der Berner Fachhochschule ist es gelungen, Wissen und Fertigkeiten in ein einziges Weiterbildungsprogramm zu intgrieren, was sich nachhaltig positiv auf die Handlungskompetenzen der Pflegepersonen und damit indirekt auf die Lebensqualität der Menschen mit einer Demenzerkrankung auswirkt

    Theses De Emptione Et Venditione

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    Quas D. A. O. Praeside ... Domino Casparo Bitschio ... Publici exercitii gratia Cal. Maij ... pro ingenii sui tenuitate defendere conabitur Matthaeus Berner Argentoratensi

    Nouvelle publication : Ch. Berner & D. Thouard (dirs.)

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    Christian Berner & Denis Thouard (dirs.), L'Interprétation. Un dictionnaire philosophique. Paris, Vrin, 2015, 561 p.  ISBN : 978-2-7116-2628-1. L'interprétation est au coeur de notre intelligence de nous-mêmes, des autres et du monde. C'est pourquoi ses méthodes jouent un rôle essentiel dans les différents champs des sciences humaines (philosophie, critique littéraire, sciences sociales, psychanalyse, anthropologie, droit, histoire, science politique, théologie ...). Il est donc indispensable..

    MeSH term explosion and author rank improve expert recommendations

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    Information overload is an often-cited phenomenon that reduces the productivity, efficiency and efficacy of scientists. One challenge for scientists is to find appropriate collaborators in their research. The literature describes various solutions to the problem of expertise location, but most current approaches do not appear to be very suitable for expert recommendations in biomedical research. In this study, we present the development and initial evaluation of a vector space model-based algorithm to calculate researcher similarity using four inputs: 1) MeSH terms of publications; 2) MeSH terms and author rank; 3) exploded MeSH terms; and 4) exploded MeSH terms and author rank. We developed and evaluated the algorithm using a data set of 17,525 authors and their 22,542 papers. On average, our algorithms correctly predicted 2.5 of the top 5/10 coauthors of individual scientists. Exploded MeSH and author rank outperformed all other algorithms in accuracy, followed closely by MeSH and author rank. Our results show that the accuracy of MeSH term-based matching can be enhanced with other metadata such as author rank

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    "Closing the R&D Gap, Evaluating the Sources of R&D Spending"

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    Both spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.
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