2,854 research outputs found

    Botulinum neurotoxin for head and neck disorders/ [edited by] Andrew Blitzer, Brian E. Benson, Diana N. Kirke

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    Includes bibliographical references and index"Senior author Dr. Andrew Blitzer is an internationally renowned pioneer on the use of botulinum neurotoxin for functional disorders, with unparalleled expertise on this topic. Joined by co-editors Brian Benson and Diana Kirke, with multidisciplinary contributors, Botulinum Neurotoxin for Head and Neck Disorders Second Edition fills a gap in the medical literature. The unique textbook focuses on the use of botulinum neurotoxins for functional disorders of the head and neck, though with some aesthetic indications. The second edition reflects the latest advances and understanding of existing and emerging applications for botulinum neurotoxins, including new treatment paradigms, revised pharmacology, and an updated review of the literature in all chapters. Twenty superbly illustrated chapters cover the management of hyperfunctional, pain, and hypersecretory syndromes of the head and neck. Hyperfunctional motor disorders are discussed in chapters focused on blepharospasm, facial dystonia, Meige syndrome, oromandibular dystonia, spasmodic dysphonia (laryngeal dystonia), and cervical dystonia. Specific treatment approaches for pain are addressed in chapters on migraine and chronic daily tension headaches, temporomandibular disorders, and trigeminal neuralgia. The treatment of autonomic nervous system disorders is covered in chapters dedicated to Frey syndrome, facial hyperhydrosis, and sialorrhea"--Pharmacology of Botulinum Neurotoxins / Muna I. Bitar, Nikita Kohli, Maya Samman, and Andrew Blitzer -- Botulinum Neurotoxin for Blepharospasm / Amit Patel, Andrew Blitzer, and Boris L. Bentsianov -- Botulinum Neurotoxin for Facial Dystonia / Scott M. Rickert, Amy P. Wu, and Andrew Blitzer Botulinum -- Neurotoxin for Meige Syndrome / Niv Mor and Andrew Blitzer -- Botulinum Neurotoxin for Oromandibular Dystonia / Daniel Novakovic and Ajay E. Chitkara -- Botulinum Neurotoxin for Spasmodic Dysphonia / Phillip C. Song, Lucian Sulica, and Andrew Blitzer -- Botulinum Neurotoxin for Cervical Dystonia / Tanya K. Meyer, Joel Guss, and Ronda E. Alexander -- Botulinum Neurotoxin for Hemifacial Spasm and Facial Synkinesis / Lesley French Childs, Daniel Novakovic, and Scott R. Gibbs -- Botulinum Neurotoxin for Hyperfunctional Facial Lines / Brian E. Benson, Diana N. Kirke, and Andrew Blitzer -- Botulinum Neurotoxin for Upper and Lower Esophageal Spasm / Nwanmegha Young and Brian E. Benson -- Botulinum Neurotoxin for Palatal Myoclonus / Ajay E. Chitkara, Catherine F. Sinclair, and Daniel Novakovic -- Botulinum Neurotoxin for Temporomandibular Disorders, Masseteric Hypertrophy, and Cosmetic Masseter Reduction / Michael Z. Lerner and Andrew Blitzer -- Botulinum Neurotoxin Therapy in the Laryngopharynx / Craig H. Zalvan, Phillip C. Song, Nwanmegha Young, and Andrew Blitzer -- Botulinum Neurotoxin for Migraine / Rachel Kaye, Jerome Schwartz, Brian E. Benson, and William J. Binder -- Botulinum Neurotoxin for Chronic Tension Headache / Nwanmegha Young and Brian E. Benson -- Botulinum Neurotoxin for Trigeminal Neuralgia / Elizabeth Guardiani, Andrew Blitzer, Lesley French Childs, and Ronda E. Alexander -- Botulinum Neurotoxin for Frey's Syndrome / Rachel Kaye, Andrew Blitzer, and Brian E. Benson -- Botulinum Neurotoxin for Facial Hyperhidrosis / Diana N. Kirke, Daniel Novakovic, and Andrew Blitzer -- Botulinum Neurotoxin for Sialorrhea / Brianna K. Crawley, Scott M. Rickert, Senja Tomovic, and Andrew Blitzer -- Botulinum Neurotoxin for Radiation-Induced Spasm and Pain / Diana N. Kirke, Brian E. Benson, and Tanya K. Meyer1 online resourc

    "Making New Connections": interview with Brian Chikwava

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    This is an interview with Brian Chikwava, the author of critically-acclaimed *Harare North* (2009)

    Tyrosine-derived nanoparticles for the topical treatment of psoriasis

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    At the New Jersey Center for Biomaterials, a potential topical psoriasis therapy consisting of tyrosine-derived polymeric micelles (TyroSpheres™) with encapsulated drug has been developed. These TyroSpheres™ are composed of copolymers with hydrophobic blocks of oligomers of desaminotyrosyl tyrosine esters and diacids and hydrophilic blocks of poly(ethylene glycol). Encapsulated drugs include a vitamin D3 analogue, betamethasone dipropionate, and paclitaxel. Drug-loaded TyroSpheres™ offer: 1) reproducible particle sizes, 2) control of drug release rates, 3) enhancement of drug stability, 4) increased solubility by high encapsulation capacity, 5) lack of short-term cytotoxicity, and 6) the ability to improve drug delivery into the skin. Additionally, TyroSpheres™ can be incorporated into an elegant viscous formulation for skin application with no impact on homogeneity, release, or skin distribution. Analysis has revealed that TyroSpheres™ are stable for up to 4 months, significantly limiting their shelf-life potential. By implementing a rational design, research on the preparation of a dry formulation of TyroSpheresTM has been undertaken, resulting in a fully re-constitutable formulation that has demonstrated complete stability to date (6 months). A two year-long stability study has been initiated to track the properties of this formulation over time. TyroSpheres™ address the requirements of a pharmaceutically acceptable skin drug delivery carrier and offer potential in the treatment of psoriasis since they allow delivery of difficult to uptake drugs to skin strata where the disease originates.Ph. D.Includes bibliographical referencesby Brian E. Kilfoyl

    Brian Wood : Related Differences = Brian Wood : Différences connexes

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    Hanna successively considers the antithetic process that underlies Wood's creative approach, the hand and the photographic eye considered as instruments, and motifs typical of the artist's drawings. The author analyses photomontages produced between 1976 and 1993. Includes extensive quotes from an interview with the artist. Biographical notes. 6 bibl. ref

    Implementation work program

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    developed for: Oregon Department of Transportation ; developed by: DKS Associates, in partnership with Cambridge Systematics ; Brian Chandler (DKS), Lacy Brown (DKS), and Ryan Klitzsch (CS).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Mode of access: Internet from the Oregon Government Publications Collection.Text in English

    Brian Scott : Trade Show

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    Farrell studies the commercial product lines imagined by Scott and convincingly packaged as a trade show that parodies corporate strategies. Investigating the market-driven imperatives of the "technological vision", the author unveils the work's social commentary about "techno-dreamworld". Biographical notes on artist and curator. 10 bibl. ref

    Fisicalidade: potências e limites da relação entre corpo e instrumento em práticas musicais atuais

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    Trataremos de posturas composicionais e interpretativas que abordam a questão da fisicalidade presente na atuação instrumental, em situações nas quais as potencialidades do conjunto executante - instrumento são levadas a situações limite. Isso se dará levando-se em consideração as seguintes variáveis: características intrínsecas do instrumento; interação do intérprete com o instrumento; elementos mecânicos de interferência nessa relação. Serão abordadas, especialmente, obras dos compositores Helmut Lachenmann, Iannis Xenakis, Brian Ferneyhough, Aaron Cassidy e Simon Steen-Andersen. Também será abordada a produção artística do autor do trabalho.In this work we deal with music, both from the composition as well as from the performance viewpoints, in which the potentials of the relationship between performer and musical instrument are taken to limit situations. This is done with an analysis of the following elements: specific and intrinsic characteristics of an instrument; interaction between performer and instrument; mechanical elements of interference in this relationship. We will approach, specially, works of Helmut Lachenmann, Iannis Xenakis, Brian Ferneyhough, Aaron Cassidy and Simon Steen-Andersen. Recent musical pieces of the author of this work will also be mentioned

    Buscando a Gramsci en la obra de Brian Simon

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    This article examines the results of research on the work and career of Brian Simon (1915-2002), one of the leading historians of English education. It shows the theoretical inspiration for comprehensive school in Soviet psychology and the original way of interpreting Marxism by Brian Simon, that is, anti-determinism, and conviction in education as a factor of change. In addition to the collection in four volumes of Studies in the History of Education, the autobiography, A life in education, and other books by the author, the survey was based on documents and unpublished writings found in the Brian Simon Archive at the Institute of Education/UCL. The conclusions are as follows: 1. The influence of Gramsci could be found in articles and reviews, as well as the courses Professor Simon was involved in from the 1970s onwards; 2. By defending educational reforms that favored the working class, Brian Simon adopted the Marxist view of Gramsci even before knowing the main translation of his work into English (1971); 3. Although a supporter of the Soviet Union, Brian Simon’s reformist protagonism suited Gramsci’s rejection of the Soviet road to socialism since, for him, this was not the appropriate path for “western” countries and for non-revolutionary periods. Finally, the article indicates perspectives of new studies on Marxist intellectuals from different countries whose common interest was Gramsci.Este artículo examina los resultados de la investigación sobre el trabajo y la carrera de Brian Simon (1915-2002), uno de los principales historiadores de la educación inglesa. Muestra la inspiración teórica de la escuela comprensiva en la psicología soviética y la forma original de interpretar el marxismo de Brian Simon, es decir, el antideterminismo y la convicción en la educación como factor de cambio. Además de la colección en cuatro volúmenes de Estudios en Historia de la Educación, la autobiografía, Una vida en la educación y otros libros del autor, la encuesta se basó en documentos y escritos inéditos encontrados en el Archivo Brian Simon del Instituto de Educación/UCL. Las conclusiones son las siguientes: 1. La influencia de Gramsci se puede encontrar en artículos y reseñas, así como en los cursos en los que participó el profesor Simon desde la década de 1970 en adelante; 2. Al defender reformas educativas que favorecieran a la clase trabajadora, y no la vía soviética al socialismo, Brian Simon adoptó una teoría gramsciana incluso antes de conocer la traducción de su obra principal al inglés (1971); incluso antes de conocer la principal traducción de Gramsci al inglés (1971); 3. Aunque partidario de la Unión Soviética, el protagonismo reformista de Brian Simon concordaba con el rechazo de Gramsci a la vía soviética hacia el socialismo ya que, para él, ésta no era la vía adecuada para los países “occidentales” y para los períodos no revolucionarios. Finalmente, el artículo indica perspectivas de nuevos estudios sobre intelectuales marxistas de diferentes países cuyo interés común fue Gramsci.Este artigo examina os resultados da pesquisa sobre a obra e a carreira de Brian Simon (1915-2002), um dos principais historiadores da educação inglesa. Ao focar em sua forte defesa do "sistema integral" no ensino médio, que começou no final da década de 1940, o objetivo aqui é determinar em que medida há princípios gramscianos em sua concepção de educação. Além da coleção em quatro volumes de Estudos em História da Educação, a autobiografia, Uma vida na educação e outros livros do autor, a pesquisa foi baseada em documentos e escritos inéditos encontrados no Arquivo Brian Simon do Instituto de Educação/UCL. Os resultados confirmaram que a influência de Gramsci pode ser encontrada em artigos e resenhas, bem como nos cursos em que o Professor Simon esteve envolvido a partir da década de 1970
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