137 research outputs found
Enacting Culturally Relevant Pedagogy when “Mathematics Has No Color”: Epistemological Contradictions
No full textCulturally relevant pedagogy (CRP) seeks to improve equity in instruction and leverage students’ experiences by promoting academic success, cultural competence, and sociopolitical consciousness. We examine instructors’ perceptions of student identity to understand the ways undergraduate mathematics instructors are enacting or experiencing barriers to enacting CRP. Interviews with ten mathematics faculty at Hispanic-serving institutions identified two potential barriers to enacting CRP: first, instructors’ hesitance to communicate about student identity, especially with respect to race and gender; and second, instructors holding epistemologies that mathematics is culture-free. Despite these barriers, almost all interviewees implemented the academic success tenet of CRP. These barriers may prevent instruction around cultural competence and sociopolitical consciousness, which are the two tenets that most capitalize on students’ informal knowledge, identities, and cultural experiences. Changing discourse by taking more risks in conversation and inviting a more diverse range of people to the undergraduate mathematics community are potential ways to address these barriers.This article is published as Shultz, M., Close, E., Nissen, J. et al. Enacting Culturally Relevant Pedagogy when “Mathematics Has No Color”: Epistemological Contradictions. Int. J. Res. Undergrad. Math. Ed. (2023). https://doi.org/10.1007/s40753-023-00219-x. Posted with permission. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/
Personality, performance, and the effects of stress on checkered pufferfish (Sphoeroides testudineus)
No full textFew studies focus on the mechanisms that regulate consistent individual-level differences in behaviour (i.e., personality) in wild animals, despite their potential evolutionary and ecological implications. I examined whether wild checkered pufferfish (Sphoeroides testudineus) have consistent individual-level differences in locomotor activity, threat-response behaviour, swimming ability, and puffing performance. I also evaluated the relationships between these personality and performance traits. Personality and performance were compared to movements in the field. In addition, I tested whether a treatment of the stress hormone cortisol would alter personality and performance. Pufferfish exhibited personalities but these were not associated with performance or recapture in the field. Performance was consistent between the lab and the natural enclosure but activity was not. The cortisol treatment did not modify personality or performance, which suggests that these traits do not represent a stress-coping syndrome. I conclude by recommending future directions for research on stress and personality in wild animals
Marketing as Constructive Engagement
No full textThe purpose of this essay is to provoke a more comprehensive, historically accurate, and meaningful definition of marketing. Toward that outcome, the author introduces a framework for marketing that argues for constructive engagement with a complex, conflicted, and increasingly interdependent world in which marketing can and should play an important role. The framework offers a new synthesis commensurate with ideals generally espoused in macromarketing. An illustration based on longitudinal study of Vietnam is shared, with implications for current global affairs and with new directions for meaningful marketing research and practice
Continued versus interrupted targeted therapy during metastasis-directed stereotactic radiotherapy: a retrospective multi-center safety and efficacy analysis
No full textThe increasing use of targeted therapy (TT) has resulted in prolonged disease control and survival in many metastatic cancers. In parallel, stereotactic radiotherapy (SRT) is increasingly performed in patients receiving TT to obtain a durable control of resistant metastases, and thereby to prolong the time to disseminated disease progression and switch of systemic therapy. The aims of this study were to analyze the safety and efficacy of SRT combined with TT in metastatic cancer patients and to assess the influence of continuous vs. interrupted TT during metastasis-directed SRT. The data of 454 SRTs in 158 patients from the international multicenter database (TOaSTT) on metastatic cancer patients treated with SRT and concurrent TT (within 30 days) were analyzed using Kaplan-Meier and log rank testing. Toxicity was defined by the CTCAE v4.03 criteria. The median FU was 19.9 mo (range 1-102 mo); 1y OS, PFS and LC were 59%, 24% and 84%, respectively. Median TTS was 25.5 mo (95% CI 11-40). TT was started before SRT in 77% of patients. TT was interrupted during SRT in 44% of patients, with a median interruption of 7 (range 1-42) days. There was no significant difference in OS or PFS whether TT was temporarily interrupted during SRT or not. Any-grade acute and late SRT-related toxicity occurred in 63 (40%) and 52 (33%) patients, respectively. The highest toxicity rates were observed for the combination of SRT and EGFRi or BRAF/MEKi, and any-grade toxicity was significantly increased when EGFRi (p = 0.016) or BRAF/MEKi (p = 0.009) were continued during SRT. Severe (≥grade 3) acute and late SRT-related toxicity were observed in 5 (3%) and 7 (4%) patients, respectively, most frequently in patients treated with EGFRi or BRAF/MEKi and in the intracranial cohort. There was no significant difference in severe toxicity whether TT was interrupted before and after SRT or not. In conclusion, SRT and continuous vs. interrupted TT in metastatic cancer patients did not influence OS or PFS. Overall, severe toxicity of combined treatment was rare; a potentially increased toxicity after SRT and continuous treatment with EGFR inhibitors or BRAF(±MEK) inhibitors requires further evaluation
Revisiting Marketing as Constructive Engagement: Linking Policies and Managerial Practices
No full textPolicies that initiate or support responsible micromarketing institutions and practices can be some of the most important catalysts to socioeconomic development and sustainable peace and prosperity, particularly in distressed or devastated political economies. Such polices and the accordant positive marketing forces might be considered a form of constructive engagement. The consideration of constructive engagement, including the idea that managerial marketing can be complementary to macromarketing, is gaining currency among some macromarketers, and is explored in this presentation. The author discusses some evolving successful cases from fieldwork in developing, devastated, transitioning and/or recovering economies
Marketing
No full text This invited commentary is a reflection on and response to an essay on “The Long Macro View”, by Robert Lusch, who articulated key themes of human, societal and marketing evolution, and challenges marketing scholars to consider ways to reduce costs inflicted by prolific human activity, particularly (marketing) exchange. Those costs cumulatively pose existential threats to humanity; they also present opportunities, which potentially can be redressed by better understanding of conflict resolution theory, relevant marketing applications to reduce social conflict, and guidance by complementary macromarketing precepts. Consistent with some ideas in the aforementioned essay, the author of this commentary argues for constructive engagement by individuals, organizations and governments via institutional entrepreneurship, which is crucial to enhance the efficiency, effectiveness, fairness and sustainability of a complex and increasingly global macromarketing system, and the well-being and long-term survival of Homo Sapiens. </jats:p
Marketing an End to War: Constructive Engagement, Community Wellbeing, and Sustainable Peace
No full textMarkets and marketing are integral to human welfare and survival. When used however for the purposes of war and other systemically violent conflict, they can be devastating and pose an existential threat to humanity. Drawing on experience in war-ravaged and recovering economies, the author examines a stream of research on marketing systems disrupted or destroyed by war. Some underlying conditions and predictors of war and its peaceful resolution are introduced, including social traps and their mitigation or elimination. An argument is revisited for marketing as a form of constructive engagement, which must be implemented to affect and to develop equitable and sustainable marketing systems, flourishing communities, societal wellbeing and sustainable peace. The article concludes with some considerations for further research
Análisis tecnológico y funcional de algunos artefactos de hueso humano de Mundo Perdido, Tikal, Guatemala. 32. Arqueología
No full textCoe, W. R.
1959. Piedras Negras Archaeology: Artifacts, Caches and
Burials, Philadelphia, University Museum
Monographs, University of Pennsylvania.Cruz, R.
1994. “El curtido del cuero”, mecanoescrito.Inomata, T.
2001. “The Power and Ideology of Artistic
Creation. Elite Craf Specialist in Classic Maya
Society”, en Current Anthropology, vol. 42, núm. 3,
USA, University of Chicago Press, pp. 321-349.Laporte, J. P.
1987. “El Grupo 6C-XVI, Tikal, Petén: un centro
habitacional temprano”, en Memorias del primer
coloquio internacional de mayistas (del 5 al 10 de
agosto de 1985), México, IIF, Centro de Estudios
Mayas, UNAM.Leroi-Gourhan, A. (ed.)
1978. “Puntas de materia ósea”, en La Prehistoria,
Barcelona, España, Labor (Nueva Clío).
1988. El hombre y la materia: evolución y técnica,
Madrid, España, Taurus (Comunicación, 7).Lorenzo, José Luis
1965. Tlatilco III. Los artefactos, México, INAH
(Investigaciones, 7).Lowe, G. W. y P. Agrinier
1960. “The Mound 1 Caches”, en Mound 1, Chiapa
de Corzo, Chiapas, Papers New World
Archaeological Foundation, núm. 8, Provo, Utah,
Brighan Young University, pp. 55-64.Mirambell, Lorena y J. L. Lorenzo.
1974. Materiales líticos arqueológicos. Generalidades,
México, INAH, Departamento de Prehistoria,
Cuadernos de Trabajo, núm. 4.Ochoa, P. J., M. Rojas, M. Sitton y S. Zarinello
1997. “Análisis tecnológico, morfológico y
experimental de la industria
osteodontoquerática en Tlatilco, Estado de
México”, ponencia presentada en el simposio Una
estrategia bioarqueológica para el análisis del resto
óseo modificado culturalmente, IX Coloquio
Internacional de Antropología Física Juan Comas,
4 de noviembre, Querétaro.Pijoán, C. y M. E. Salas
1984. “Costumbres funerarias en Mundo Perdido
Tikal”, en Estudios en Antropologiá Biológica, II
Coloquio de Antropología Física Juan Comas,
1982, México, IIA, UNAM.Santamaría, D. y J. García-Bárcena
1984. Raspadores verticales de la Cueva de los Grifos,
México, INAH, Departamento de Prehistoria,
Cuaderno de Trabajo, núm. 22.Semenov, S.
1981. Tecnología prehistórica, Madrid, Akal
Universitaria (Arqueología, 6).Sheets, P.
1975. “Behavioral Analysis and the Structure of a
Prehistoric Industry”, en Current Anthropology,
núm. 16, pp. 368-391.Shultz, M.
1997. “Microscopio Investigation of Excavated
Skeletal Remains: A Contribution to
Paleopathology and Forensic Medicine”, en
Haglund W. D. y M. H. Sorg (eds.), Forensic
Taphonomy. The Postmortem Fate of Human Remains
CRC, USA, Press Boca Raton Florida.Talavera, A., J. M. Rojas y E. García
1998a. “Informe del análisis del material
osteológico con modificaciones culturales del
Proyecto Comalcalco, Tabasco”, México, Archivo
de la Dirección de Antropología Física, INAH,
mecanoescrito.1998b. “Informe del análisis del material
osteológico con modificaciones culturales del
Proyecto Especial Monte Albán 1992-1994”,
México, Archivo de la Dirección de Antropología
Física, INAH, mecanoescrito.1998c. “Informe del análisis del material
osteológico con modificaciones culturales
depositado en la bodega de materiales
arqueológicos de la Zona Arqueológica de
Cacaxtla, Tlaxcala”, México, Archivo de la
Dirección de Antropología Física, INAH,
mecanoescrito.2001. Modificaciones culturales en los restos óseos de
Cantona, Puebla. Un análisis bioarqueológico, México,
INAH (Científica, 432)
Development of Humanized Mice in the Age of Genome Editing.
No full textMice are the most commonly used model organisms to study human disease. Many genetic human diseases can be recapitulated by modifying the mouse genome allowing the testing of existing and novel therapeutics, including combinatorial therapeutics, without putting humans at risk. Specifically, the development of humanized mice, that is, severely immunodeficient mice engrafted with functional human hematopoietic and immune cells and tissues, has revolutionized our ability to study and model human diseases in preclinical in vivo systems. Until recently it has been challenging to develop strains of humanized mice with targeted mutations or that transgenically express human genes with site-specific mutations, and can permit optimal growth of functional human cells and tissues. However, recent advances in targeted nuclease-based genetic engineering have enabled precise modification and development of humanized mouse models at an unprecedented pace. These modifications permit optimal growth of functional human cells and tissues and can be used to replicate human genetically determined diseases. J. Cell. Biochem. 118: 3043-3048, 2017. © 2017 Wiley Periodicals, Inc. J Cell Biochem 2017 Oct; 118(10):3043-3048
- …
