1,721,231 research outputs found
Insufficienza mitralica post-ischemica. Trattamento e follow-up
Full text linkIl rigurgito mitralico post-ischemico (RMI) è una complicanza frequente dell'infarto miocardico. L'anuloplastica riduttiva è una tecnica chirurgica correttiva frequentemente utilizzata per il trattamento del RMI ma i relativi benefici a distanza non sono ancora completamente chiariti. Nel presente studio abbiamo valutato l'impatto dell'anuloplastica riduttiva in 156 pazienti mediante controllo ecocardiografico e contatto telefonico dopo un follow-up medio di 2 anni. L'anuloplastica è risultata procedura sicura (1.2% mortalità operatoria). Tuttavia offre risultati migliori in pz che non presentano al momento della chirurgia una disfunzione ventricolare avanzata (FE>35%. In presenza di un Ventricolo sx con rimodellamento avanzato al momento della chirurgia, l'anuloplastica è associata ad un aumento del rischio di ricorrenza di RMI e di mancato reverse remodelling. Tali limiti si traducono in un peggioramento dei risultati in termini di sopravvivenza complessiv
The search for long-term outcome predictors
Full text linkThe most suitable technique for revascularisation in patients with left main or multivessel coronary artery disease is still widely debated (1-3). A growing number of randomised controlled trials as well as data from meta analyses have compared both coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) with drug-eluting stents (DES)
Commentary: On-X and St Jude Medical mechanical prostheses—A paradoxic concept; they are equal but different!
No full textCoronary artery bypass grafting (CABG) vs. percutaneous coronary intervention (PCI) in the treatment of multivessel coronary disease:Quo vadis? -A review of the evidences on coronary artery disease
Full text linkThe optimal treatment of ischemic coronary artery disease (CAD) is still controversial. A number of randomized controlled trials (RCT) and several meta-analyses have been performed and are inspiring the current guidelines. However, a univocal consensus on the optimal therapeutic strategy for multivessel disease has still not been reached yet. We reviewed the current evidence on this topic, focusing on both RCT and meta-analyses. From both short and long-term studies, it emerges that in patients with multivessel disease, coronary artery bypass grafting (CABG) is associated with better survival, lower rates of major cardiovascular events (specifically myocardial infarction or stroke) and repeat revascularization as compared with percutaneous coronary intervention (PCI) with drug-eluting stents.</p
Commentary:To underfit and to overfit the data. This is the dilemma
Full text linkRisk modeling should always consider the drawback of overfitting due to the inclusion of a large number of parameters
Invasiveness of left- and right-sided infective endocarditis:Does pressure explain pathology?
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Preoperative and intraoperative variables to predict mortality:Which comes first, the chicken or the egg?
Full text linkIn risk modeling, model specification should be based primarily on theoretic considerations, rather than empirical or methodologic ones
Letter by Benedetto et al Regarding Article, "Importance of Refractory Pain and Hypertension in Acute Type B Aortic Dissection: Insights From the International Registry of Acute Aortic Dissection (IRAD)
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