13,544 research outputs found

    Papers of Alan Bell

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    This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/68456Typescripts of radio broadcasts by Bell on 3DB at 6.55 p.m. nightly. Headed "Commentary", they concern the war, including the homefronts of Australia and Britain.113979 Acquisition: [1987.0114] "Papers of Alan Bell

    The Administrator of Norfolk Island, Mr Alan Kerr [picture] /

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    (P627/1-12); Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an10714329-1

    The Administrator of Norfolk Island, Mr Alan Kerr [picture] /

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    (P627/2-1); Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an10714329-2

    The Administrator of Norfolk Island, Mr Alan Kerr and his wife Judy [picture] /

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    (P627/2-15); Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an10714329-3

    Expression and function of Wnt-inducible signalling protein 1 in idiopathic pulmonary fibrosis

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    Idiopathic pulmonary fibrosis (IPF) is a progressive, fatal fibrotic interstitial lung disease affecting older adults. It has poor prognosis and clinical interventions are limited. IPF is characterised by the build-up of fibrotic extracellular matrix in the lung interstitium, leading to progressively impaired gas exchange and eventual death. The cause of IPF is unknown but is thought to involve repeated microinjuries to lung tissue leading to chronic activation of wound healing pathways such as Wnt, TGF-β and hypoxia inducible factor (HIF) signalling. IPF tissue is characterised by the presence of fibroblastic foci – aggregates of matrix-secreting fibroblasts and myofibroblasts which drive fibrosis by producing stiffened collagen which exhibits abnormal, bone-type crosslinking.CCN proteins are a family of proteins with similar protein structure, which affect cell signalling by interacting with other proteins to modulate their function. Wnt-inducible signalling protein 1 (WISP-1) is a Wnt-driven CCN protein that has roles in bone development and stem cell survival. While WISP-1 expression is upregulated in IPF tissue, its role in disease pathogenesis is unclear. It is hypothesised that WISP-1 is dysregulated in fibroblastic foci, and that this contributes to IPF pathogenesis by affecting protein-protein interactions. Thus, the aims of this project were to (i) characterise the localisation of WISP-1; (ii) to identify drivers of WISP-1 expression; and (iii) to identify potential functions of WISP-1 by determining what proteins it interacts with.WISP-1 expression was found to localise to fibroblastic foci in a laser-capture microdissection (LCMD) RNAseq dataset of control and IPF alveolar septae and fibroblastic foci. This was confirmed by RNAscope in-situ hybridisation. WISP1 was identified as being expressed in two distinct fibroblast types in an IPF single cell RNAseq dataset, myofibroblasts and senescent, profibrotic HAS1-high fibroblasts. Gene signatures from these cells were identified in LCMD fibroblastic focus RNAseq data using CibersortX in-silico cell sorting. Gene expression signatures associated with HIF and TGF-β signalling were found to be upregulated in WISP1 expressing mesenchymal cells. Treatment of primary lung fibroblasts from healthy or IPF donors with HIF activators or hypoxic conditions in vitro led to induction of WISP1 which was greatly augmented in IPF lung fibroblasts, suggesting WISP-1 expression is HIF driven in IPF. Using an affinity purification-mass spectrometry (AP-MS) workflow to identify protein interaction partners of GFP-tagged WISP-1, the mitogen fibroblast growth factor 2 (FGF2) and the mitochondrial cell survival factors voltage dependent anion channel 1 (VDAC1) and prohibitin (PHB) were identified as WISP-1 interaction partners in MRC-5 cultured lung fibroblasts. Interactions of WISP-1 with FGF2 and VDAC1 were confirmed by western blotting or using binding assays.In conclusion, WISP-1 is localised in fibroblastic foci, where its expression occurs in two distinct, profibrotic fibroblast types: myofibroblasts and IPF-specific HAS-1 high fibroblasts. In vitro studies demonstrate that WISP-1 expression in IPF fibroblasts is driven by HIF signalling and that WISP-1 interacts with proteins known to affect cell survival and proliferation. These findings are consistent with a role for WISP-1 in IPF pathogenesis

    Estimating diameter inside bark at various heights in young Douglas fir trees

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    Faqir Mohammad Khan, Graduate Student, John F. Bell, Professor of Forest Management, Alan B. Berg, Professor of Forest Science.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Includes bibliographical references (page 2).Mode of access: Internet from the Oregon Government Publications Collection.Text in English

    Photograph - Computer Centre. Alan Bell in the New Computer Building. Jul 1986

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    This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/285949Computer Centre. Alan Bell in the New Computer Building. Jul 1986291810 Item: [2003.0003.02927] "Photograph - Computer Centre. Alan Bell in the New Computer Building. Jul 1986

    Alan Moore Comics as Performance, Fiction as Scalpel

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    Eclectic British author Alan Moore (b. 1953) is one of the most acclaimed and controversial comics writers to emerge since the late 1970s. He has produced a large number of well-regarded comic books and graphic novels while also making occasional forays into music, poetry, performance, and prose. In Alan Moore: Comics as Performance, Fiction as Scalpel , Annalisa Di Liddo argues that Moore employs the comics form to dissect the literary canon, the tradition of comics, contemporary society, and our understanding of history. The book considers Moore's narrative strategies and pinpoints the main thematic threads in his works: the subversion of genre and pulp fiction, the interrogation of superhero tropes, the manipulation of space and time, the uses of magic and mythology, the instability of gender and ethnic identity, and the accumulation of imagery to create satire that comments on politics and art history. Examining Moore's use of comics to scrutinize contemporary culture, Di Liddo analyzes his best-known works-- Swamp Thing, V for Vendetta, Watchmen, From Hell, Promethea , and Lost Girls . The study also highlights Moore?s lesser-known output, such as Halo Jones, Skizz , and Big Numbers , and his prose novel Voice of the Fire. Alan Moore: Comics as Performance, Fiction as Scalpel reveals Moore to be one of the most significant and distinctly postmodern comics creators of the last quarter-century.Intro -- Contents -- Preface and Acknowledgments -- Introduction -- CHAPTER 1. Formal Considerations on Alan Moore's Writing -- CHAPTER 2. Chronotopes: Outer Space, the Cityscape, and the Space of Comics -- CHAPTER 3. Moore and the Crisis of English Identity -- CHAPTER 4. Finding a Way into Lost Girls -- Conclusion -- Notes -- Bibliography -- Index -- A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- L -- M -- N -- O -- P -- Q -- R -- S -- T -- U -- V -- W -- Y -- ZEclectic British author Alan Moore (b. 1953) is one of the most acclaimed and controversial comics writers to emerge since the late 1970s. He has produced a large number of well-regarded comic books and graphic novels while also making occasional forays into music, poetry, performance, and prose. In Alan Moore: Comics as Performance, Fiction as Scalpel , Annalisa Di Liddo argues that Moore employs the comics form to dissect the literary canon, the tradition of comics, contemporary society, and our understanding of history. The book considers Moore's narrative strategies and pinpoints the main thematic threads in his works: the subversion of genre and pulp fiction, the interrogation of superhero tropes, the manipulation of space and time, the uses of magic and mythology, the instability of gender and ethnic identity, and the accumulation of imagery to create satire that comments on politics and art history. Examining Moore's use of comics to scrutinize contemporary culture, Di Liddo analyzes his best-known works-- Swamp Thing, V for Vendetta, Watchmen, From Hell, Promethea , and Lost Girls . The study also highlights Moore?s lesser-known output, such as Halo Jones, Skizz , and Big Numbers , and his prose novel Voice of the Fire. Alan Moore: Comics as Performance, Fiction as Scalpel reveals Moore to be one of the most significant and distinctly postmodern comics creators of the last quarter-century.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries

    [Letter] 1849 January 17 [to] Robert Allan / Alan Stevenson.

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    See also the Stevenson family\u27s connection to the Northern Lighthouse Board as well as a biography of Robert Stevenson and the family tree (http://www.nlb.org.uk/historical/stevenson.htm).Alan Stevenson expresses his regrets that he will not be able to attend the Carson Class Dinner as he is leaving town, but "should otherwise, have been most happy to attend." The Carson Class Club was comprised of former students of the Edinburgh Royal High School, who had attended the classes of Dr. Aglionby Ross Carson, between 1815 and 1821. Alan worked as a lighthouse engineer on 12 lighthouses in the tradition of his father Robert Stevenson, engineer to the Northern Lighthouse Board from 1808-1842 (see also, letter from Robert Stevenson re: Bell Rock Lighthouse). Alan\u27s brother Thomas was the father of Robert Louis Stevenson, the novelist who wrote classics like _Treasure Island_ . Recipient Robert Allan may be Robert Allan, son of famous mineralogist Thomas Allan

    An analysis of english four skills in “when english rings a bell” english textbook based on alan cunningsworth criteria

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    In the process of learning English, teaching materials are needed to strengthen and support the learning process, including textbooks. Therefore, this research analysed English four skills in “When English Rings a Bell” English textbook for seventh grade of Junior High School based on Alan Cunningsworth criteria. The Research problem of the study were: (1) What types of skills are there in “When English Rings a Bell” English textbook?, and (2) How is the contain of skills found in “When English Rings a Bell” English textbook based on Alan Cunningsworth criteria?”. Therefore, the purposes of the study were: (1) To describe types of skills in “When English Rings a Bell” English textbook., and (2) To describe the contain of skills found in “When English Rings a Bell” English textbook based on Alan Cunningsworth criteria. In carrying out this research, researcher used a qualitative approach with content analysis method. Data collected by carrying out observation checklist, interview, and documentation. The main research findings were: (1) English four skills (listening, speaking, reading and writing) found in the English textbook "When English Rings a Bell" for seventh grade of Junior High Schools published by the Ministry of Education and Culture, and (2) English skills such as listening, speaking, reading and writing shows the results of a checklist based on Alan Cunningsworth found among them on page 4 as listening skills, page 101 as speaking skills, page 105 as reading skills, and page 137 as writing skills. Abstract Didalam proses belajar bahasa khususnya bahasa Inggris, bahan ajar sangat diperlukan untuk memperkuat dan mendukung proses pembelajaran, diantaranya adalah buku pelajaran. Oleh karena itu, penelitian ini meneliti tentang empat keterampilan bahasa Inggris yang ada di buku pelajaran “When English Rings a Bell” untuk kelas VII SMP sederajat berdasarkan kriteria Alan Cunningsworth. Rumusan masalah dari penelitian ini adalah: (1) Jenis keterampilan apa saja yang ada di buku pelajaran Bahasa Inggris “When English Rings a Bell” ?, and (2) Bagaimana isi keterampilan yang ditemukan di buku pelajaran bahasa Inggris “When English Rings a Bell” berdasarkan Alan Cunningsworth?. Oleh karena itu, tujuan dari penelitian ini adalah: (1) Untuk mengetahui jenis keterampilan yang ada di buku pelajaran Bahasa Inggris “When English Rings a Bell”, dan (2) Untuk menggambarkan isi keterampilan yang ditemukan di buku pelajaran bahasa Inggris “When English Rings a Bell” berdasarkan Alan Cunningsworth. Dalam melaksanakan penelitian ini, peneliti menggunakan pendekatan kualitatif dengan metode analisi konten. Data dikumpulkan dengan melaksanakan ceklis observasi, wawancara, dan dokumentasi. Hasil yang diperoleh adalah: (1) Empat keterampilan bahasa Inggris (mendengarkan, berbicara, membaca, dan menulis) ditemukan dalam buku pelajaran bahasa Inggris "When English Rings a Bell" untuk kelas VII SMP yang diterbitkan oleh Kementerian Pendidikan dan Kebudayaan, dan (2) Keterampilan bahasa Inggris seperti mendengarkan, berbicara, membaca dan menulis menunjukan hasil dari ceklis berdasarkan Alan Cunningsworth seperti yang ditemukan diantaranya di halaman 4 terkait keterampilan mendengarkan, halaman 101 terkait keterampilan berbicara, halaman 105 terkait keterampilan membaca, dan halaman 137 terkait keterampilan menulis
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