2,260 research outputs found
Author Lili Mendoza discusses intellectual freedom in her work
No full textHear Lili Mendoza describe how intellectual freedom motivates her creative endeavors. Lili Mendoza is a fiction writer, poet, translator and was born in Panama. She is the author of the short story collection Corazón de charol a-go-gó (2009). Her stories and poetry have been anthologized in Panama, Costa Rica, Spain, Peru, and the U.S., and showcased at literary events in Europe. An active member of the Theater Guild of Ancon, Mendoza also collaborates in musical and dance performances.
Interviewer Brian JK Mille
Measurement of the Decays B -> jK and B -> jK*.
No full textWe have obsd. the decays B -> jK and jK* in a sample of over 45 million B mesons collected with the BABAR detector at the PEP-II collider. The measured branching fractions are B(B+ -> jK+) =(7.7+1.6-1.4+-0.8)* 10-6, B(B0 -> jK0) =(8.1+3.1-2.5+-0.8)* 10-6, B(B+ -> jK*+)=(9.7+4.2- 3.4+-1.7)*10-6, and B(B0 ->jK*0) =(8.7+2.5-2.1+-1.1)* 10-6. We also report the upper limit B(B+ -> jp+
Measurement of the Decays B -> jK and B -> jK*.
No full textWe have obsd. the decays B -> jK and jK* in a sample of over 45 million B mesons collected with the BABAR detector at the PEP-II collider. The measured branching fractions are B(B+ -> jK+) =(7.7+1.6-1.4+-0.8)* 10-6, B(B0 -> jK0) =(8.1+3.1-2.5+-0.8)* 10-6, B(B+ -> jK*+)=(9.7+4.2- 3.4+-1.7)*10-6, and B(B0 ->jK*0) =(8.7+2.5-2.1+-1.1)* 10-6. We also report the upper limit B(B+ -> jp+
Profitability of milk production and its impact factors at JK Otsa Talu Ltd in 2009 - 2011
No full textKäesoleva bakalaureusetöö eesmärgiks oli välja selgitada OÜ JK Otsa Talu piimatootmise kulud ja analüüsida piimatootmise tasuvust mõjutavaid tegureid aastatel 2009 - 2011 ning esitada autoripoolseid ettepanekuid piima tootmise tasuvuse tõstmiseks uuritavas ettevõttes.
Tasuvuse analüüsimiseks on teostatud Osaühingu JK Otsa Talu piimakarjakulude struktuuri ja -dünaamika analüüs, piima kokkuostuhinna analüüs ning piimatootmise tootlikkuse analüüs. Aastate 2009 – 2011 kohta on teostatud analüüs, kus käsitletakse ettevõtte koondnäitajaid: kogukulusid ja –tulusid, käibe- ja kulurentaablust ning ühe haru st piimatootmise osanäitajaid nagu piima tootmisomahind, lehma produktiivsus ja kattetulu looma kohta.The aim of the current bachelors thesis was to find out what the milk production costs of JK Otsa Talu Ltd. were and to analyse milk production profitability impact factors in 2009 – 2011 and to search for opportunities to increase the profitability of milk production.
To analyse the profitability in JK Otsa Talu Ltd. the author has carried out an analysis of livestock costs structure and dynamics, milk prices, productivity and gross margin, comparisons have been made between enterprise production costs, dairy cows productivity, enterprise total costs and revenue, profit margin and cost margin analysis in 2009 – 2011. Also a comparison has been made between the data of JK Otsa Talu Ltd. and the data of other mixed producers type and milk producers belonging to the same group based on the FADN database
Modulation of hole-injection in GaInN-light emitting triodes and its effect on carrier recombination behavior
No full textThe effects of the hole injection modulated by using a three-terminal GaInN-based light emitter, light-emitting triode (LET), on carrier recombination behavior and efficiency droop are investigated. It was found that the lateral electric field created by applying voltage bias between the two anodes effectively reduces efficiency droop as well as dynamic conductance of LETs. Detailed analyses of LETs under various operation conditions by APSYS simulations reveal that the asymmetry in carrier transport between electrons and holes is alleviated by promoted injection of hot holes over the potential barrier, increasing the hole concentration as well as the radiative recombination rate in the multiple quantum well active region. (C) 2015 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution 3.0 Unported License.110Ysciescopu
A unified and integrated numerical-analytical approach for evaluation of Jk-integrals of an interfacial crack in orthotropic and isotropic bimaterials
No full textA new unified and integrated method for the numerical-analytical calculation of Jk-integrals of an in-plane traction free interfacial crack in homogeneous orthotropic and isotropic bimaterials is presented. The numerical algorithm, based on the boundary element crack shape sensitivities, is generic and flexible. It applies to both straight and curved interfacial cracks in anisotropic and/or isotropic bimaterials. The shape functions of semi-discontinuous quadratic quarter point crack tip elements are correctly scaled to adapt the singular oscillatory near tip field of tractions. The length of crack is designated as the design variable to compute the strain energy release rate precisely. Although an analytical equation relating J1 and stress intensity factors (SIFs) exists, a similar relation for J2 in debonded anisotropic solids for decoupling SIFs is not available. An analytical expression was recently derived by this author for J2 in aligned orthotropic/orthotropic bimaterials with a straight interface crack. Using this new relation and the present computed Jk values, the SIFs can be decoupled without the need for an auxiliary equation. Here, the aforementioned analytical relation is reconstructed for cubic symmetry/isotropic bimaterials and used with the present numerical algorithm. An example with known analytical SIFs is presented. The numerical and analytical magnitudes of Jk for an interface crack in orthotropic/orthotropic and cubic symmetry/isotropic bimaterials show an excellent agreement
Are language production problems apparent in adults who no longer meet diagnostic criteria for attention-deficit/hyperactivity disorder?
No full textIn this study, we examined sentence production in a sample of adults (N = 21) who had had attention-deficit/hyperactivity disorder (ADHD) as children, but as adults no longer met DSM-IV diagnostic criteria (APA, 2000). This “remitted” group was assessed on a sentence production task. On each trial, participants saw two objects and a verb. Their task was to construct a sentence using the objects as arguments of the verb. Results showed more ungrammatical and disfluent utterances with one particular type of verb (i.e., participle). In a second set of analyses, we compared the remitted group to both control participants and a “persistent” group, who had ADHD as children and as adults. Results showed that remitters were more likely to produce ungrammatical utterances and to make repair disfluencies compared to controls, and they patterned more similarly to ADHD participants. Conclusions focus on language output in remitted ADHD, and the role of executive functions in language production
MicroRNAs in cardiac arrhythmia: DNA sequence variation of MiR-1 and MiR-133A in long QT syndrome.
No full textLong QT syndrome (LQTS) is a genetic cardiac condition associated with prolonged ventricular repolarization, primarily a result of perturbations in cardiac ion channels, which predisposes individuals to life-threatening arrhythmias. Using DNA screening and sequencing methods, over 700 different LQTS-causing mutations have been identified in 13 genes worldwide. Despite this, the genetic cause of 30-50% of LQTS is presently unknown. MicroRNAs (miRNAs) are small (∼ 22 nucleotides) noncoding RNAs which post-transcriptionally regulate gene expression by binding complementary sequences within messenger RNAs (mRNAs). The human genome encodes over 1800 miRNAs, which target about 60% of human genes. Consequently, miRNAs are likely to regulate many complex processes in the body, indeed aberrant expression of various miRNA species has been implicated in numerous disease states, including cardiovascular diseases. MiR-1 and MiR-133A are the most abundant miRNAs in the heart and have both been reported to regulate cardiac ion channels. We hypothesized that, as a consequence of their role in regulating cardiac ion channels, genetic variation in the genes which encode MiR-1 and MiR-133A might explain some cases of LQTS. Four miRNA genes (miR-1-1, miR-1-2, miR-133a-1 and miR-133a-2), which encode MiR-1 and MiR-133A, were sequenced in 125 LQTS probands. No genetic variants were identified in miR-1-1 or miR-133a-1; but in miR-1-2 we identified a single substitution (n.100A> G) and in miR-133a-2 we identified two substitutions (n.-19G> A and n.98C> T). None of the variants affect the mature miRNA products. Our findings indicate that sequence variants of miR-1-1, miR-1-2, miR-133a-1 and miR-133a-2 are not a cause of LQTS in this cohort
Antipsychotics and Torsadogenic Risk: Signals Emerging from the US FDA Adverse Event Reporting System Database
No full textBackground: Drug-induced torsades de pointes (TdP) and related clinical entities represent a current regulatory and clinical burden. Objective: As part of the FP7 ARITMO (Arrhythmogenic Potential of Drugs) project, we explored the publicly available US FDA Adverse Event Reporting System (FAERS) database to detect signals of torsadogenicity for antipsychotics (APs). Methods: Four groups of events in decreasing order of drug-attributable risk were identified: (1) TdP, (2) QT-interval abnormalities, (3) ventricular fibrillation/tachycardia, and (4) sudden cardiac death. The reporting odds ratio (ROR) with 95 % confidence interval (CI) was calculated through a cumulative analysis from group 1 to 4. For groups 1+2, ROR was adjusted for age, gender, and concomitant drugs (e.g., antiarrhythmics) and stratified for AZCERT drugs, lists I and II (http://www.azcert.org, as of June 2011). A potential signal of torsadogenicity was defined if a drug met all the following criteria: (a) four or more cases in group 1+2; (b) significant ROR in group 1+2 that persists through the cumulative approach; (c) significant adjusted ROR for group 1+2 in the stratum without AZCERT drugs; (d) not included in AZCERT lists (as of June 2011). Results: Over the 7-year period, 37 APs were reported in 4,794 cases of arrhythmia: 140 (group 1), 883 (group 2), 1,651 (group 3), and 2,120 (group 4). Based on our criteria, the following potential signals of torsadogenicity were found: amisulpride (25 cases; adjusted ROR in the stratum without AZCERT drugs = 43.94, 95 % CI 22.82-84.60), cyamemazine (11; 15.48, 6.87-34.91), and olanzapine (189; 7.74, 6.45-9.30). Conclusions: This pharmacovigilance analysis on the FAERS found 3 potential signals of torsadogenicity for drugs previously unknown for this risk
Relasi Pembantu Presiden Dalam Kabinet Kerja Jokowi-jk
No full textThe conflicts between Minister of Maritime and Natural Resources Rizal Ramli and vice president Jusuf Kalla in electricity projects, Minister of State-Owned Companies and Minister of Transportation regarding fast-train development, Minister of Energy and Mineral Resources and Minister of State-Owned Companies regarding management policy of Masela Block, are conflicts inside the circle of the President's assistants. These conflicts are implications from the obscurity of positions and authorities of said assistants. The author then researched with juridical empiric method. Through this research, it is hoped that the effective formulation of relation between the President's assistants can be found.IntisariPerselisihan antara Menko bidang Kemaritiman dan SDA Rizal Ramli terhadap Wapres Jusuf Kalla dalam proyek listrik, Menteri BUMN dan Menteri Perhubungan dalam pembangunan kereta cepat, Menteri ESDM dan Menteri BUMN dalam kebijakan pengelolaan Blok Masela merupakan perseteruan di lingkaran pembantu presiden. Perseteruan tersebut merupakan implikasi dari ketidakjelasan kedudukan dan wewenang para pembantu presiden. Penulis kemudian meneliti permasalahan ini dengan metode yuridis empiris. Melalui penelitian ini, diharapkan dapat ditemukan formulasi pengaturan dan upaya untuk mewujudkan relasi pembantu presiden dalam Kabinet Jokowi-JK yang efektif dan efisien
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