34 research outputs found
Characterization Of Mixed Gels
No full textThis Dissertation / Report is the outcome of investigation carried out by the creator(s) / author(s) at the department/division of Central Food Technological Research Institute (CFTRI), Mysore mentioned below in this page
Settlement Analysis of Shallow Foundation on Frictional Soil Under Combined Effect of Static and Cyclic Load
No full textNot Available
No full textNot AvailableThe environment is used as a broad umbrella term for all sources of allergens which may cause allergic hypersensitive reaction of the immune system of humans and animals. Hypersensitivity is the name given to a state in which an immune response damages the body's own tissues. It is a process of reactions of antigen with antibody or sensitised lymphocytes that are harmful to the host. When an adaptive immune response occurs in an exaggerated or inappropriate form causing tissue damage, the term ‘hypersensitivity ’is applied. There are four or five types of hypersensitivity that are often described. Research has focused on understanding each hypersensitivity reaction to ensure appropriate therapeutic recommendations. This article elucidates the details of different types of hypersensitivities and different methods of detection.Not Availabl
Factors Influencing Transient Response of Shallow Strip Footing on Granular Soil Subjected to Vertical Pulse Load
No full textA High Gain Elliptical Slot Antenna for Lower C-band and X-band Application
No full textA novel design of printed CPW-fed planar elliptical slot antenna with transformed circular patch is presented here for dual-band application. The obtained impedance band finds application in lower C-band satellite communication and entire X-band with significant gain. Electromagnetic wave simulator HFSS® is used to simulate the structure and the study of parameter behaviour is carried out. The performance of the proposed antenna in terms of return loss, radiation pattern and gain are analysed. Furthermore, the same structure is designed and simulated with microstrip feed line. An imperial formula in terms of axial length and ellipticity ratio of the elliptical slot is formulated to find the lower edge frequency of impedance bandwidth
Settlement of Surface Strip Foundation Resting on Soft Clay Subjected to Vertical Cyclic Load
No full textDRUG UTILISATION, ADVERSE DRUG REACTION PROFILE AND TREATMENT OUTCOME OF PNEUMONIA IN UNDER-FIVE CHILDREN IN A TERTIARY CARE HOSPITAL: A CROSS-SECTIONAL STUDY.
No full textBackgrounds
Childhood pneumonia is a leading cause of morbidity and mortality among children under 5 years old worldwide. Despite global efforts to prevent and manage this condition, the improper and irrational use of antimicrobials is one of the greatest hinderance to achieving the target.
Objectives: The study aimed to evaluate the drug utilization pattern, treatment outcome, and monitoring of frequency and severity of Adverse Drug Reactions (ADRs) with its causality assessment among under-five pneumonia cases.
Methods
This observational cross-sectional study was conducted on 118 diagnosed cases of pneumonia aged 2 months to 5 years. Data were collected from treatment records and parents' responses and analyzed using Microsoft Excel 2016 and SPSS version 22.0.
Results
Among 118 under-five pneumonia cases, 88.1% recovered and 11.9% required ICU care. Most were male (75.4%), aged 2–12 months (60.2%), and from rural areas (73%). Complications were linked to female gender and parental smoking. Adverse outcomes were associated with fever, cough, delayed treatment, prolonged hospitalization, and multiple antibiotic use. Prescription analysis (536 cases) showed polypharmacy (mean 4.52 drugs), universal antibiotic, and injection use, with 85.92% prescribed by generic name and 88.93% from the essential drug list. Of 50 ADRs, diarrhea (58%) from ceftriaxone was most common.
Interpretation: Female gender and parental smoking were associated with higher ICU admissions, highlighting the need for targeted clinical strategies in managing pediatric pneumonia.
Conclusion
The study concluded that prompt and appropriate treatment is pivotal for resolving pneumonia in children and reducing morbidity and mortality. Monitoring prescriptions and drug utilization studies helps in detecting and reducing irrational prescribing while offering feedback to prescribers.
Recommendation
Raising awareness among healthcare providers and caregivers, regularly educating on proper antibiotic use, implementing prescribing guidelines, and involving patients in ADR reporting can enhance treatment outcomes and minimize adverse drug reactions in under-five pneumonia cases
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No full textNot AvailableThe present experiment aimed to compare the two most commonly used compounds of arsenic (sodium arsenite and arsenic trioxide) for their effect on blood metabolites, thyroid hormones, and oxidant/antioxidant status in guinea pigs. Twenty-one adult guinea pigs were randomly divided into three equal groups. Animals in group T1 (control) were fed a basal diet, whereas 50 ppm arsenic was added in the basal diet either as sodium arsenite (T2) or arsenic trioxide (T3) and fed for 11 weeks. Serum aspartate aminotransferase and alanine aminotransferase activities were significantly increased along with a decrease in blood hemoglobin level in both the arsenic-administered groups. The level of erythrocytic antioxidants (catalase, superoxide dismutase, reduced glutathione, glutathione-S-transferase, and glutathione reductase) was decreased and lipid peroxidation was elevated upon arsenic exposure. Serum thyroid hormone levels were reduced and arsenic levels in tissues increased in both the arsenic-exposed groups, irrespective of the arsenic compound. Thus, sodium arsenite and arsenic trioxide exerted similar adverse effects on blood metabolic profile, antioxidant status, and thyroid hormones in guinea pigs.Not Availabl
The curative and antioxidative efficiency of ivermectin and ivermectin + vitamin E-selenium treatment on canine Sarcoptes scabiei infestation
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