1,721,040 research outputs found
Caracterización de suelos de Barquisimeto - Estado Lara, Venezuela, Aplicando métodos geofísicos y geotécnicos
Caracterización de suelos de Barquisimeto - Estado Lara, Venezuela, Aplicando métodos geofísicos y geotécnicos
Integration of simulated moving bed chromatography and enzymatic racemization for the production of single enantiomers
Integration of enantioseparation by simulated moving bed (SMB) and mild enzymatic racemization enables the production of single enantiomers from a racemic mixture in theoretically 100% yield and hence overcomes the 50% yield limitation of conventional SMB processes. We implemented such a process consisting of a Chirobiotic TAG column-SMB, an amino acid racemase-containing enzyme membrane reactor, and a nanofiltration unit for concentration of the distomer-enriched SMB raffinate prior to racemization on lab-scale for the production of enantiopure D-methionine. The integrated process scheme was operated continuously for over 30 h without significant variations in product concentration and purity and with a yield of 93.5%, demonstrating the feasibility of this integrated process concept. Furthermore, a rational analysis of the integrated process on the basis of a short-cut model was conducted. The process model consists of a true moving bed equilibrium stage model to represent the SMB, a continuous stirred tank reactor model with reversible Michaelis–Menten kinetics to represent the enzyme membrane reactor, a nanofiltration model and feed node mass balances, and enabled the identification of optimal operating points (flow rate ratios, enzyme concentration) at a variety of process specifications and objectives. Optimal operating points were calculated for different cost distributions between the applied materials such as stationary phase, enzyme, solvent, and nanofiltration membrane. By assigning plausible pricing data and lifetimes to the respective materials, variable costs for the specific process considered in this work were estimated
Tectonics of the Friuli area (NE Italy): results from continuous GPS and kinematic modeling
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
- …
