232 research outputs found
Erratum: Immunogenicity, antigenicity and epitope mapping of Salmonella InvH protein: An in silico study
No full textThere was an error in the author list of the published article.
Two authors (T Hashempour, Z Hasanshahi) requested to remove from the authors lists. After obtaining the agreement of the authors and the corresponding author, Editor-in-Chief accept the corrections as listed below.
The correct author list is:
Behzad Dehghani, Iraj Rasooli
We apologize for any inconvenience this may have caused.
Erratum for:
Immunogenicity, antigenicity and epitope mapping of Salmonella InvH protein: An in silico study
B Dehghani, T Hashempour, Z Hasanshahi, I Rasooli
J Curr Biomed Rep. 2020; 1(1): 9-16
Correction to:Value of 2-[18F]FDG-PET/CT in identifying immune-related adverse events in patients with melanoma or non-small cell lung cancer: a systematic scoping review (Clinical and Translational Imaging, (2024), 12, 2, (187-195), 10.1007/s40336-024-00618-3)
No full textIn this article the author name Mohammad Naghavi-Behzad was incorrectly written as Mohammad Naghavi-Bezhad. The original article has been corrected.</p
Optimizing parallel I/O performance of HPC applications
No full textParallel I/O is an essential component of modern High Performance Computing (HPC). Obtaining good I/O performance for a broad range of applications on diverse HPC platforms is a major challenge, in part because of complex inter-dependencies between I/O middleware and hardware. The parallel file system and I/O middleware layers all offer optimization parameters that can, in theory, result in better I/O performance. Unfortunately, the right combination of parameters is highly dependent on the application, HPC platform, and problem size/concurrency. Scientific application developers do not have the time or expertise to take on the substantial burden of identifying good parameters for each problem configuration. They resort to using system defaults, a choice that frequently results in poor I/O performance. We expect this problem to be compounded on exascale class machines, which will likely have a deeper software stack with hierarchically arranged hardware resources.
We present a line of solution to this problem containing an autotuning system for optimizing I/O performance, I/O performance modeling, I/O tuning, I/O kernel generation, and I/O patterns. We demonstrate the value of these solution across platforms, applications, and at scale.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2017-12-01The student, Babak Behzad, accepted the attached license on 2015-11-20 at 13:31.The student, Babak Behzad, submitted this Dissertation for approval on 2015-11-20 at 13:45.This Dissertation was approved for publication on 2015-11-23 at 13:41.DSpace SAF Submission Ingestion Package generated from Vireo submission #8816 on 2016-03-02 at 14:06:01Made available in DSpace on 2016-03-02T20:23:36Z (GMT). No. of bitstreams: 4
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Previous issue date: 2015-11-23Embargo set by: Seth Robbins for item 91322
Lift date: 2018-03-02T20:24:31Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemU of I Only Restriction Lifted for Item 91322 on 2018-03-03T10:15:34Z
Dental caries and athletes
No full textDear Editor-in-Chief Performing intense exercise on the body's organs is associated with various risks. At the same time, it is necessary for athletes to be aware of the dangers of intense exercise, for this purpose, studies have shown that the health of the oral cavity helps improve the performance of athletes (Gallagher et al., 2020). On the other hand, the disorder in the oral cavity with intense exercise significantly impacts the quality of life of athletes.One of the most common diseases of oral cavity diseases caused by exercise is dental caries (D’Ercole et al., 2016). Dental caries is a chronic disease among humans and is one of the most common oral diseases worldwide. It is an important oral and dental disease that prevents achieving and maintaining oral health in all age groups. Dental caries refers to the local destruction of sensitive dental hard tissues by acidic by-products resulting from the bacterial fermentation of carbohydrates food. This disease is caused by an ecological imbalance between dental minerals and oral biofilms (plaque) (Selwitz et al., 2007; Thean et al., 2007; Yadav et al., 2017).According to statistics announced by international organizations related to dentistry, approximately 2.43 billion people (about 36% of the population) around the world have dental caries in their permanent teeth and it affects about 620 million people or 9% of the population in milk teeth (Yadav et al., 2017). The statistics of athletes suffering from dental caries show that oral and dental cavity disorders among athletes were first recognized during the 1958 World Cup in Sweden. So that one dentist performed 118 tooth extraction surgeries on 33 athletes from different countries (Soares et al., 2014). Dental caries has also been reported among athletes in Olympic competitions. However, in the 2004 Athens Olympics, the visit of athletes by dentists took the second place among the visits of athletes to different departments of the clinic. In the 2008 Beijing Olympics, 1.600 people visited the dental department of the clinic at the venue of the competition. Similarly, in the 2012 London Olympics, 55% of the athletes were suffering from tooth decay (Needleman et al., 2013; Vougiouklakis et al., 2008; Yang et al., 2011). Azeredo et al. (2020), in a review article, investigated the prevalence of dental caries in athletes. The findings showed that the prevalence of dental caries among athletes is 46.25% (Azeredo et al., 2020). Larson et al. (2015), in a study, evaluated the intervention of exercise and energy drink consumption with health risk behaviors among adults. Findings suggest that health care providers should differentiate energy drink consumption and exercise from other unhealthy behaviors when designing programs for adults (Larson et al., 2015).Research conducted in the field of exercise shows that exercise plays a role in reducing PH and increasing blood CO2. On the other hand, the decrease in the PH of saliva is related to the level of Co2 in the blood and the level of Co2 in the blood increases after exercise, and as a result, a high concentration of Co2 in the blood is transferred to the oral saliva, which is effective in reducing the PHof the saliva. In the same context, when the PH of saliva drops below the value of 5.5 that is assumed as the “Critical PH”, hydroxyapatite crystals in enamel begin to dissolve and decalcified areas occur (Ceyhan et al., 2020; Farsi, 2008; Milosevic et al., 1997; Okada et al., 2012). Borchers et al. (2022), analyzed saliva in their study to monitor intense exercise among male ultra-marathon runners. In this study, 9 healthy men who finished the distance of 160 km were selected as the statistical population of the research. The salivary markers were compared with blood markers following acute exercise stress in ultra-marathon runners at three baselines, shortly after the ultramarathon competition and after recovery. The findings showed that different blood markers and salivary cortisol had significant changes after the ultra-marathon running (Borchers et al., 2022).Thus, it is recommended that athletes should be aware of the biochemical variables and other factors leading to dental caries and observe the oral and dental hygiene requirements. Moreover, due to the fact that athletes of various sports are affected by oral cavity diseases, it is necessary that athletes of competitive sports such as football, swimming, track and field, etc., pay more attention to the health of their oral cavity
Competition in dual-channel supply chains: The manufacturers' channel selection
No full text© 2020 The Author(s) Innovative selling channels have brought about opportunities as well as challenges for upstream manufacturers. The past few years have witnessed both the success and failure of manufacturers with different channel strategies. To explore the rationale of different channel strategies in various contexts, we develop a model to analyze a manufacturer's channel selection decision among three channel strategies, i.e., a direct-channel strategy, a retail-channel strategy, and a dual-channel strategy consisting of both direct and retail channels. The model rests on the channel differentiation in terms of consumers’ channel preferences and operating costs of retail and direct channels. Specifically, we incorporate the action of a competitor and track down its influence on the focal manufacturer's channel preference. Our research clarifies the role of competition in the market and offers insights into the competitive nature of business in real life. Results show that the manufacturer's channel preference depends not only on the channels’ operating costs and consumers’ channel preferences but also on the competitor's channel strategy. We find that symmetric manufacturers can adopt asymmetric strategies as Nash equilibria and also that there are situations where no Nash equilibrium exists. We characterize the Nash equilibria in the channel selection game based on the exogenous parameters of the model
Cytokine-mediated FOXO3a phosphorylation suppresses FasL expression in hemopoietic cell lines: Investigations of the role of Fas in apoptosis due to cytokine starvation
No full textWe have investigated phosphatidylinositol 3-kinase (PI3K)-dependent survival signalling pathways using several cytokines in three different hemopoietic cell lines, MC/9, FDC-P1, and TF-1. Cytokines caused PI3K- and PKB-dependent phosphorylation of FOXO3a (previously known as FKHRL1) at three distinct sites. Following cytokine withdrawal or PI3K inhibition, both of which are known to lead to apoptosis, there was a loss of FOXO3a phosphorylation, and a resulting increase in forkhead transcriptional activity, along with increased expression of Fas Ligand (FasL), which could be detected at the cell surface. Concurrently, an increase in cell surface expression of Fas was also detected. Despite the presence of both FasL and Fas, there was no detectable evidence that activation of Fas-mediated apoptotic events was contributing to apoptosis resulting from cytokine starvation or inhibition of PI3K activity. Thus, inhibition of FOXO3a activity is mediated by the PI3K–PKB pathway, but regulation of FasL is not the primary means by which cell survival is regulated in cytokine-dependent hemopoietic cells. We were also able to confirm increased expression of known FOXO3a targets, Bim and p27kip1. Together, these results support the conclusion that mitochondrial-mediated signals play the major role in apoptosis of hemopoietic cells due to loss of cytokine signalling. [ABSTRACT FROM AUTHOR]Peer reviewedfinal article publishedCytokineSignal transductionapoptosisTranscription factorProtein kinas
Bilingualism, Monolingualism and Social Health: A Comparative Study Behzad Khedri , Farideh Sadat Momeni Masuole
No full textdimensions in the two groups of students in favor of bilingual students, and the variables such as age, marriage, field of study, socioeconomic status, religious beliefs and communication skills were influential on the social health of both groups. Also, the results of the regression showed that 29% of the influence on the dependent variable of this study was interpreted by the independent variables. In addition, the communication skill is the strongest variable predictor with a rate of 66%. Keyword: Social Health, Social Integration, Students, Language Bilingualism, Monolingualism and Social Health: A Comparative Study Behzad Khedri[1] , Farideh Sadat Momeni Masuole[2] Received: 18/2/2017 Accepted: 30/4/2018 Abstract There are mental influencing factors among students in the educational context such as educational stress, ethnic and cultural contradictions and the existence of political, belief, racial as well as gender discrimination, which can affect various aspects of student life and the health of this stratum, especially their social dimension could be endangered. Regarding the relationship between language, as a fundamental cultural component, and social health which has not been studied in social health research. In other words, the language of different ethnicities can provide unity, integrity, coherence and participation, or can a common language affect health and its social dimension or not? This study aims to answer the mentioned question by investigating bilingual students (ethnicities) and the monolinguals (those who speak only one language). In the following, we intend to explain what factors affect the social health of each group? The method of this study was survey and data was collected through questionnaires. The statistical population is Sanandaj University students and the sample included 384 individuals by the Cochran formula. The results of this study showed that there is a significant difference between the total social health and its [1]. PhD Student of Social Work, AllamehTabatabaiiUniversity, Tehran. (Corresponding Author). [email protected] [2]. Master of Sociology, ShahedUniversity. [email protected]
The data on the aerobic training with or without calorie restriction and muscular levels of Irisin and muscular FNDC5 concentration in obese male Wistar rats
No full textThe present data article aims at investigating the muscular levels of Irisin, FNDC5, and UCP1 in male Wistar rats during the aerobic exercise with or without calorie restriction (CR). Twenty four, 8-week-old male Wistar rats (190±16 g) were selected and purchased for the research. After obesity induction by high-fat diet, the animals were randomly divided into three groups: exercise EX (n = 8), EX-CR (n = 8) and CO as control (n = 8). EX exercised 6 sessions per week and EXCR exercise 3 sessions + 3 days caloric restriction per week. The Irisin (Cat.No:CK-E91266 & Intra-Assay: CV<10%), FNDC5 (Cat.No:CK-E91393 & Intra-Assay: CV<10%) levels were assessed by the special Rat ELISA Kit (EASTBIOPHARM, China, under licensed by the United States). Muscular Irisin concentrations in EX group were higher than other groups. In addition, FNDC5 concentrations in EX group was higher than those in other groups. Keywords: Training, Animal model, Diet, Exercis
Exercise training in polluted environment: A narrative review with focus on combat physical fitness
No full textAir pollution is one of the most important problems of recent decades, which has serious toxic effects on human health and the environment. Sources of pollution vary from small units of cigarettes and natural sources such as volcanic activity to large volumes of emissions from car engines and industrial activities or even radioactive ones. Today, there are various pollutants around the world that negatively affect human health. Walking and being in a polluted environment can increase the penetration of pollutants such as lead in the body. Increasing physical activity such as long-term running, which is widely used in some jobs such as military jobs, can increase the activity of muscle tissue, and as a result, the cardiovascular system becomes more active and helps absorb more pollutants. Lead acetate is a possible carcinogen in humans, which is absorbed into the human body by pollutants. There is evidence that lead compounds can cause lung, brain, stomach, and kidney cancer in humans. However, pollution does not include air pollution only, and noise pollution can endanger human health as well. Since some occupations such as those of military experience various types of noise, as well as chemical and radioactive pollution and the point that having high physical fitness is essential for these people, this study examined the impact of various pollutants on the military personnel and also sought to see whether exercising and having high physical fitness of military personnel can reduce the stress caused by the pollution
Need to Perform Rehabilitation Exercises at Home by Parents of Children with Neurological Diseases to Maintain Performance During COVID-19 Lockdown
No full textWith the outbreak of the novel pandemic coronavirus disease 2019 (COVID-19) worldwide, many pediatric rehabilitation clinics have closed to support social &physical distancing and therapist like other people are staying in their homes. There is common concern of parents and caregivers that how and with which quality children's rehabilitation exercises should be proceed. Most children with neurological diseases have problems such as muscle spasticity, range of motion limitation, muscle shortening, balance loss, mobility and movement impairment. The aim of this research was to summarize the necessaries of home based rehabilitation exercises program during quarantine period
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