1,720,955 research outputs found
Infective Complications After Spinal Instrumentation
No full textSurgical site infection (SSI) is an uncommon
complication of spine surgery, but when it happens,
it represents a huge challenge both for the
surgeon and the patient, with potentially catastrophic
consequences if not treated quickly. In fact, patients with post-operative spine
infection require longer hospital lengths of stay,
have higher re-operation rates, and are put at high
risk of chronic pain, neurological complications,
pseudarthrosis that can lead to implant failure,
and even death if they involve the spinal cord.
Progress was made in reducing the risk of infection
by adopting a standardized protocol in the
management of the patient both pre-, intra-, and
post-operative, and by better understanding of
risk factors
Classic Kaposi sarcoma: Diagnostics, treatment modalities, and genetic implications – A review of the literature
Full text linkBackground and purpose: Classic Kaposi sarcoma (CKS) is a rare vascular disease mainly found in populations of Mediterranean origin. The pathogenesis involves Human Herpes Virus 8 (HHV8) and genetic mutations such as SNP309 in the MDM2 gene. The recently discovered BPTF mutation in cells of CKS patients demonstrated higher latency-associated nuclear antigen (LANA) staining and altered vital transcriptomics, implicating a potential role in tumorigenesis. This review explores the genetic underpinnings and treatments for CKS.
Material and methods: A comprehensive literature search was conducted from 2004 to 2024, yielding 70 relevant papers. Ongoing clinical trials investigating novel treatments such as talimogene and abemaciclib were included in the search and presented in the results.
Results: Clinical diagnosis and treatment can be challenging as the number of studies on CKS and treatment modalities is limited. Treatment strategies vary by disease stage, with local therapies like surgical intervention and radiation therapy recommended for early stages, while systemic therapies are considered in cases of systemic disease.
Interpretation: While advancements in CKS treatment offer hope, further studies on immunotherapy are warranted to broaden the therapeutic options, such as anti-bromodomain or BPTF-targeted therapy
Nursing Leadership in a Post-Pandemic Elective Orthopaedic Theatre Department: A Detailed Thematic Analysis of an Open-Ended Qualitative Survey
Full text linkThe COVID-19 pandemic has impacted nursing theatre staff, departmental
activity, and delivery of services to patients. This work-based project aimed to investigate the
challenges of nursing leadership in an elective orthopaedic department at current times. Methods:
The study collected qualitative data exploring theatre staff’s expectations from leadership, offering
insight on how the pandemic has influenced the way of working and exploring how the future
in this unit may look. The answers from 20 practitioners to an anonymised open-ended survey
were examined using thematic analysis. Results: The participants described a leader as a good
communicator who focuses on empowering others and supporting the team, identified by the
majority as a senior team member. From the findings, three topics were identified: immediate
changes, delayed changes, and pre-existing conditions. The answers painted a reality that is complex
and multifaceted, where numerous variables play a part in the physical and mental health of each
candidate, impacting their performance as well as their work/life balance. Overall, the strongest
subjects recurring in the findings were the need for nursing leadership to focus on supporting
staff with training opportunities, to actively plan for a reduction in staffing shortages, and to be
constantly mindful of staff well-being. Conclusions: This study pointed out that the need for constant
communication with their staff, building honest relationships, and being a reliable leader, focused on
empowering others and supporting the team were important factors for the nursing management
during the COVID-19 pandemic and post-COVID-19 era
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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