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    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    Impact of chronic kidney disease on myostatin accumulation and muscle regeneration : role of indoxyl sulfate

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    La myostatine est une protéine dont le rôle est de freiner la croissance musculaire. Les concentrations sanguines de myostatine augmentent au cours de l’insuffisance rénale chronique (IRC). Certains auteurs font l’hypothèse d’une augmentation de sa production par les muscles sous l’effet de l’indoxyl sulfate (IS), une toxine urémique dérivée du tryptophane. Dans cette thèse nous montrons grâce à des modèles murins d’IRC et dans un modèle cellulaire qu’il n’y a pas de surproduction de myostatine par les cellules musculaires sous l’effet de l’IRC ou de l’IS. La myostatine s’accumule au cours de la MRC du fait d’une diminution de son élimination rénale plutôt que du fait d’une augmentation de production.Nous analysons ensuite l’effet de l’IS sur la régénération musculaire grâce à un modèle de lignée cellulaire de myoblastes (cellules souches permettant la régénération musculaire) murins, les C2C12. Nous montrons que l’exposition des C2C12 à l’IS durant leur différenciation en myotubes conduit à des myotubes plus fins et contenant moins de noyaux que les contrôles, suggérant que l’IS inhibe la régénération musculaire. En analysant les gènes impliqués dans la différenciation des myoblastes en myotubes, nous mettons en évidence que l’IS inhibe l’expression du gène Myf6 qui code pour un facteur de différenciation appelé Mrf4. Mrf4 est un facteur de transcription impliqué dans la phase tardive de la différenciation (fusion myocytes-myocyte ou fusion myocyte-myotube) ainsi que dans l’innervation des fibres musculaires. Ainsi, l’IRC conduit à la sarcopénie par une diminution de la capacité de régénération musculaire induite par l’IS via l’inhibition de l’expression de Myf6.Myostatin is a protein secreted by mature muscle cells that inhibits striated muscle growth. Recent publications suggest that myostatin accumulates during chronic kidney disease (CKD). Some hypothesize that it is overproduced by muscle cells during CKD under the effect of indoxyl sulfate, an indolic uremic solute. In the first part of this thesis, using mice models and cellular culture of myocytes, we demonstrate that there is no overproduction of myostatin in muscle cells during CKD or after exposure to indoxyl sulfate, suggesting that myostatin accumulates because of a lack of renal clearance rather than overproduction during CKD.In the second part of the thesis, we analyze the impact of indoxyl sulfate on muscle regeneration. We used an in vitro cellular culture model of murine myoblasts (pluripotent cells which proliferate and differentiate in mature muscle cells) called C2C12. We demonstrate that when C2C12 cells are exposed to indoxyl sulfate during differentiation, final myotubes are thinner and exert less nucleus per myotube, suggesting that indoxyl sulfate inhibits muscle cell differentiation. We then analyzed the genes expression of the Muscle Regulating Factors which are transcription factors that organize and regulate differentiation. We report on that indoxyl sulfate inhibits the transcription of the Myf6 gene. Mrf4 (the protein coded by the Myf6 gene) is a transcription factor regulating the late phase of transcription (myocyte-myocyte fusion and myocyte-myotube fusion) as well as the innervation of muscle fibers. Thus, CKD could lead to sarcopenia via impaired muscle regeneration due to Myf6 transcription inhibition by indoxyl sulfate

    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used

    Author Under Sail The Imagination of Jack London, 1893-1902

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    In Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
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