656 research outputs found
Silêncio e (des)solução em Cartas a Posêidon de Cees Nooteboom
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão, Programa de Pós-Graduação em Literatura, Florianópolis, 2015.É a partir do abandono dos deuses em Cartas a Posêidon (2012), do escritor Cees Nooteboom, que a presente dissertação busca refletir sobre a criação de uma imagem poética do estatuto do homem nos dias atuais, cujo enfoque reside nas inúmeras descontinuidades e rupturas presentes no texto de escritor neerlandês. Através da Carta sobre o humanismo, de Martin Heidegger, e Regras para o parque humano, de Peter Sloterdijk, o trabalho propõe uma breve discussão sobre a epístola enquanto ferramenta humanista e, no caso de Nooteboom, a sua inabilidade em fazer amigos, resultado da disrupção do dialogismo pelo insistente silêncio divino. Utilizando-se do conceito de Stimmung e os estudos de Leo Spitzer e Hans Gumbrecht sobre o tema, a dissertação procura observar a criação de determinadas atmosferas ao longo do texto, cuja essência nega o significado original do termo Stimmung enquanto harmonia. Por intermédio do pensamento de Jean-Luc Nancy acerca do mito e a sua base atual como negação de sua fundação original, o trabalho busca pensar a inoperância da carta como espaço de proliferação da narrativa. Valendo-se de A Comunidade Inconfessável, de Maurice Blanchot, a formação da comunidade tem como base a sua própria ausência em um movimento contínuo aqui proposto como (des)solução. Por fim, através da contribuição de Susan Sontag em ?Estética do silêncio?, a dissertação propõe uma comparação dos fragmentos de Nooteboom com a pintura neerlandesa do século XVII, o Stilleven, e a sua natureza silente e imóvel que em Nooteboom culminam em tremor, ruído.Abstract : It is from the abandonment of the gods in Letters to Poseidon (2012), of the writer Cees Nooteboom, that this study tries to reflect on the creation of a poetic image of the status of man nowadays whose focus lies in the many discontinuities and breaks in the text the Dutch author. By Letter on Humanism, from Martin Heidegger, and Rules for the human zoo, by Peter Sloterdijk, the work proposes a brief discussion of the epistle as humanistic tool and, in the case of Nooteboom, its inability to make friends as a result of disruption of dialogism by the insistent divine silence. Using the concept of Stimmung and studies of Leo Spitzer and Hans Gumbrecht on the subject, the dissertation tries to observe the creation of specific atmospheres throughout the text, whose essence denies the original meaning of the term Stimmung as harmony. Through the thought of Jean-Luc Nancy about the myth and its current base as denial of its original foundation, the work aims to rethink the ineffectiveness of communication as the narrative space proliferation and the formation of a community, drawing on The Unavowable Community, from Maurice Blanchot, whose base lies in its very absence, in continuous motion proposed here as (dis)solution. Finally, through the contribution of Susan Sontag in "Aesthetics of Silence", the study proposes a comparison of Nooteboom fragments with the Dutch painting of the seventeenth century, Stilleven, and its silent and motionless nature that in Nooteboom culminates into tremor, noise
Frugal innovation: Some theoretical observations from innovation-economic and social-entrepreneurial perspectives
No full textThis chapter’s aims to link frugal innovation (FI) to some theoretical notions. First, it presents a brief overview of what FI is in order to identify characteristics that can be linked to theoretical notions. Second it links the concept of FI to 1) existing theoretical notions on profit-induced innovators and how these contribute to economic development and transformation, and 2) a conceptual way of thinking based on social entrepreneurs and their motives and opportunities to overcome resource constraint by designing and developing frugal innovation. Two takeaways on furthering theoretical attempts to understand frugal innovations are presented. The first one is working out of Comprehensive Schumpeterian models where dynamic patterns of polycentric innovation networks can be examined thoroughly. The second way is working further on the role of (networks of) social entrepreneurs as frugal innovators and providing them a broader validity.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Economics of Technology and Innovatio
De gezonde stad vraagt om genuanceerd debat
No full textGezonde, duurzame stedelijke ontwikkeling is een complex vraagstuk dat vraagt om een serieus debat. Reinout Kleinhans en Cees-Jan Pen betogen dat we het debat niet moeten verengen tot verdichten of binnen- versus buitenstedelijk bouwen, zoals Jos Feijtel dat recent deed in deze kolommen. Het gaat om hoe we de kwaliteit en integraliteit van gezonde stedelijke ontwikkeling verhogen en bewaken – binnen de context van de politieke druk op ‘bouwen, bouwen, bouwen’.Urban Studie
Synthetic life on a chip
No full textIn this article, we argue that on-chip microfluidic systems provide an attractive technology when it comes to designing synthetic cells. We emphasize the importance of the surrounding environment for both living systems in nature and for developing artificial self-sustaining entities. On-chip microfluidic devices provide a high degree of control over the production of cell-like synthetic entities as well as over the local microenvironment that these soft-matter-based synthetic cells experience. Rapid progress in microfluidic fabrication technology has led to a variety of production and manipulation tools that establish on-chip environments as a versatile platform and arguably the best route forward for realizing synthetic life.Accepted Author ManuscriptBN/Cees Dekker La
How do molecular motors fold the genome?
No full textA potential mechanism of DNA loop extrusion by molecular motors is discussed.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.BN/Cees Dekker LabBN/Benjamin Rowland La
Tracking the Dark Side on a shoe-string budget
No full textMeaningful SSA work on earth-orbiting satellites can be done on a shoe-string budget, with modest, off the shelf equipment. This has been shown by an informal group of self-funded Independent Space Observers (“ISO’s”) organized around the Seesat-L mailing list. Literally from their backyards, they track some 200 “classified” objects – objects that are not in the public orbital catalogues – using very simple equipment: from binoculars and stopwatch on the ‘old skool’ end, to DSLR’s or sensitive CCTV or CMOS/CCD cameras with fast photographic lenses and GPS time control on the sophisticated end. In this paper, a brief outline is provided on the techniques and equipment used by Seesat-L members and an example is given on how a new 'classified' launch is located and tracked, often within hours of launch. It is discussed why the whole concept of keeping the orbits of certain space assets “classified” is problematic: not only is it unrealistic, but it also goes against core notions of transparency and accountability regarding activities in space.Astrodynamics & Space Mission
Earth grazing meteor over Northern Europe, September 22, 2020, 03:53UTC
No full textAn earth grazing meteor was observed over Northern Europe on September 22, 2020, around 03:53UTC.
From Dwingeloo in the Netherlands, two images were obtained.
2020-09-22T03:53:33.445.fits (FITS format, BGGR bayer matrix)
2020-09-22T03:53:33.445.png (Debayered image)
2020-09-22T03:53:50.135.fits (FITS format, BGGR bayer matrix)
2020-09-22T03:53:50.135.png (Debayered image)
The image times refer to the start of the exposure
Nanopores as versatile single-molecule tools: From DNA turbines to protein sequencing
No full textGreen Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.BN/Cees Dekker La
The NEOtrap – en route with a new single-molecule technique
No full textThis paper provides a perspective on potential applications of a new single-molecule technique, viz., the nanopore electro-osmotic trap (NEOtrap). This solid-state nanopore-based method uses locally induced electro-osmosis to form a hydrodynamic trap for single molecules. Ionic current recordings allow one to study an unlabeled protein or nanoparticle of arbitrary charge that can be held in the nanopore's most sensitive region for very long times. After motivating the need for improved single-molecule technologies, we sketch various possible technical extensions and combinations of the NEOtrap. We lay out diverse applications in biosensing, enzymology, protein folding, protein dynamics, fingerprinting of proteins, detecting post-translational modifications, and all that at the level of single proteins – illustrating the unique versatility and potential of the NEOtrap.BN/Cees Dekker La
Reply to: On the statistical foundation of a recent single molecule FRET benchmark
No full textBN/Cees Dekker La
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