1,722,172 research outputs found
Computer-assisted histology for the diagnosis of Barrett s Esophagus
No full textS.171-172Gastroesophageal reflux disease (GERD) is one of the most com- mon and in the frequency increasing diseases in the western world. In- testinal metaplasia, or Barrett s Esophagus , is a precancerous conditi- on and complication of GERD. A large interobserver variation is known in histopathology of Barrett s Esophagus. Hence, it makes sense to sup- port pathologists with an automated pre-analysis of the images. Goal of this study is the evaluation of possibilities to differentiate three types of tissue automatically, namely Barrett s Esophagus (BE), normal cardiac mucosa (CA) and normal squamous epithelium of the esophagus (EP)
Barrett, S M, NX76405
No full textThis record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/370371Surname: BARRETT
Given Name(s) or Initials: S M
Military Service Number or Last Known Location: NX76405
Missing, Wounded and Prisoner of War Enquiry Card Index Number: 36710180631
Item: [2016.0049.02698] "Barrett, S M, NX76405
The development of malignant Barrett´s esophagus on the basis of long-term follow-up of 1438 Patients
No full textDa der Barrett-Ösophagus als wichtigster Risikofaktor für die Entwicklung des Adenokarzinoms des Ösophagus gilt, werden für alle Barrett-Patienten regelmäßig endoskopisch-bioptische Nachkontrollen empfohlen. Allerdings schreitet der Barrett-Ösophagus neueren Studien zufolge so selten zum Karzinom fort, dass viele Experten das aktuelle Überwachungsmodell für kostenineffektiv halten. Ziel dieser Arbeit war es daher, anhand von Langzeitverlaufskontrollen von 1438 Barrett-Patienten die Entwicklung des malignen Barrett-Ösophagus zu untersuchen. Die Ergebnisse dieser Arbeit deuten an, dass Patienten mit initialer low-grade intraepithelialer Neoplasie signifikant häufiger einen malignen Barrett-Ösophagus entwickeln als Patienten ohne initiale intraepitheliale Neoplasie. Darüber hinaus wurden im Rahmen dieser Arbeit maligne Progressionen bevorzugt während des ersten Überwachungsjahres entdeckt.As Barrett´s esophagus is supposed to be the most important risk factor for the development of esophageal adenocarcinoma, endoscopic-bioptic follow-up is recommended regularly for all patients with Barrett´s esophagus. However, according to recent studies Barrett´s esophagus rarely progresses to carcinoma, therefore many experts consider the current surveillance programs cost-ineffective. Hence, based on long-term follow-up-examiations of 1438 patients with Barrett´s esophagus, it was intended here to examine the development of malignant Barrett´s esophagus. The results of this dissertation indicate that Patients with initial low-grade intraepithelial neoplasia significantly develop malignant Barrett´s esophagus more frequently than patients without initial intraepithelial neoplasia. Furthermore, malignant progressions were predominantly detected during the first year of follow-up
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Preoperative Gastric Acid Secretion and the Risk to Develop Barrett`s Esophagus After Esophagectomy for Chagasic Achalasia
No full textThe aim of this study was to determine the contribution of preoperative gastric secretory and hormonal response, to the appearance of Barrett`s esophagus in the esophageal stump following subtotal esophagectomy. Thirty-eight end-stage chagasic achalasia patients submitted to esophagectomy and cervical gastric pull-up were followed prospectively for a mean of 13.6 +/- 9.2 years. Gastric acid secretion, pepsinogen, and gastrin were measured preoperatively in 14 patients who have developed Barrett`s esophagus (Group I), and the results were compared to 24 patients who did not develop Barrett`s esophagus (Group II). In the group (I), the mean basal and stimulated preoperative gastric acid secretion was significantly higher than in the group II (basal: 1.52 vs. 1.01, p = 0.04; stimulated: 20.83 vs. 12.60, p = 0.01). Basal and stimulated preoperative pepsinogen were also increased at the Group I compared to Group II (Basal = 139.3 vs. 101.7, p = 0.02; stimulated = 186.0 vs. 156.5, p = 0.07. There was no difference in preoperative gastrin between the two groups. Gastritis was present during endoscopy in 57.1% of the Group I, while it was detected in 16.6% of the Group II, p = 0.014. Barrett`s esophagus in the esophageal stump was associated to high preoperative levels of gastric acid secretion, serum pepsinogen, and also gastritis in the transposed stomach
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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