1,721,114 research outputs found

    Multi-state models for hospitalizations of heart failure patients in Trieste

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    In Italy, heart failure (HF) is the most common clinical diagnosis among people over 65 and about 80,000 new cases per year are recorded [1]. This is a chronic condition whose incidence is strictly connected with age. A very flexible tool for modelling the chronic nature of this disease is multi-state model. Multi-state models are based on continuous time stochastic process, that can have Markov or semi-Markov property. In this presentation we show a multi-state model in which the states are the admission from and discharge to the first five hospitalizations, and death, an absorbing state. This representation aims at describing the main characteristics of heart failure patients’ hospitalization progression considering various covariates recorded

    Competing risks between mortality and heart failure hospital re-admissions: a community-based investigation from the Trieste area

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    Predictors of mortality and readmission among patients hospitalized for heart failure (HF) were investigated in a large, unselected population of the Trieste area. The cohort of 4666 patients survived at the index admission in the period 2009-2014 was followed after discharge. Incidence of mortality and re-HF admission within 30 days and one year were computed, by comparing cumulative incidence probabilities with cause-specific Kaplan-Meier curves. Competing risks regression was used to find factors associated respectively with re-HF admission and death. Two distinct risk profiles were obtained, particularly for early outcomes, useful for better targeting treatment of these high-risk patients

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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