3,672 research outputs found
La historia del derecho romano de Castillejo. A propósito de su reimpresión.
No full textLa autora aborda el estado de la enseñanza del derecho romano en el primer tercio del siglo XX en las facultades de derecho de España y su relación con otros países occidentales. Toma como pretexto para sus notas la reedición de la histona del derecno
romano publicada en 1935 por Castillejo.The author describes the standing of Roman law teaching in Spanish law schools during the first part of the XX century and how it relates with its teachig in other western countries. She bases her discussion of this topic on a new edition ot Castillejo
1935 book, The History of Román Law.Publicad
Human herpesvirus 8 cellular gene modulation
No full textP0663 Human herpesvirus 8 cellular gene modulation
Barbara Matteoli*
1
, Rita Romano
2
,FrancescaTabacchi
2
, Moreno Ferroni
1
1 LAMM,SRL,Lucca, Italy,
2 Department of Public Health and Infectious Diseases,Sapienza University of Rome,
Rome, Italy
Background:Sinceinflammation is the basis of viral pathogenesis and may beinduced either directly by thevirus
or by thecell in responseto infection, theexpression pattern of cellular genes involved in this process was
investigated in human epithelial and lymphoid cells infected with Human herpes virus 8 (HHV8) .
Materials/methods:Theexpression of 297 human genes involved in 65 pathways associated with inflammation
have been studied in HEK293 and PBMC cells 24h after infection with HHV8 (A1 and C3 strains) by DualChip
Microarray.Signal quantification was performed by SilverQuant Image Viewer and analysis software(Eppendorf,
Germany) and SPSS 16.0 for Windows (SPSS, USA) with two way ANOVA followed by Scheffecontrast.
Results:Expression ratios of most of the genes werecloseto 1 or changed only <2-fold cutoff (in positive or
negativevalue), suggesting that they were not significantly changed in consequenceto HHV8 infection. Overall,a
higher number of genes resulted modulated in HHV8-infected HEK293 cells with respect to PBMCs. A robust
increasein theexpression was found in genes involved in inflammation (i.e., AGT, CCR8, CXCR4, IL-6, IL-9, IL10RA,
IL-17, IL-23A), signal transduction (i.e.,FGF5,FGF7, MAP3K1, MAPk9m TGFBR1,TRAF2),cellular cycle(IGFBP1),
immuneresponse(i.e., IL-16,TLR4),apoptosis (TNFSF4,TNFSF11),and others genes belonging to different
categories (i.e., BMP4, BMPR2,EPHA3, HGFBP1, RUNX1, RUNX2,SP1).With a >2-fold threshold filter gene
modulation as significant,a high numbers of genes resulted significantly modulated both in HEK293 cell lineand
PBMCs infected both with the A1 (169 and 104 genes, respectively) and C3 subtypes (131 and 93 genes,
respectively). Next, to increasethesignificance, only those genes with >4-fold changes in their expression were
considered. A total of 24 genes resulted strongly induced,especially after A1 subtypeinfection.Thecomparison of
transcriptional profiling between both viral subtypes showed that only 4 genes arestrongly induced by different
viral subtypes (i.e., BMP4, BMPR2, RUNX2 and TNFSF11).
Conclusions: New human genes have been involved in HHV8 infection;commonly modulated genes may be
used as target for antiviral/chemiotherapic treatmen
Fuzzy inclusion and similarity through coherent conditional probability
No full textOur aim is to study some specific fuzzy relations (inclusion and similarity) in the framework of the interpretation of fuzzy theory in terms of coherent conditional probability
Il diritto penale nel canone di Mario Romano
No full textThis paper deals with the extension and the extraordinary scientific value of the works written by a great Master in Criminal Law, such as Mario Romano. The Author briefly presents some of the most relevant contributions given by Professor Mario Romano to the Criminal Science, first of all his "Commentario sistematico del codice penale" (Systematic Commentary on the penal code), a unique work. Finally, the paper talks about some topics which have been developed inside the work "Studi in onore di Mario Romano" (Studies in Honour of Mario Romano)
Fuzzy relations in a coherent conditional probability setting
No full textOur aim is to study some specific fuzzy relations (e.g., inclusion, similarity, etc.) in the framework of the interpretation of fuzzy theory in terms of coherent conditional probability
Deliberation and journalism
No full textThe first chapter in 'International Journalism and Democracy' re-examines current ideas about the role of journalism in promoting democracy, introducing the concept of "deliberative journalism". 'Deliberation and Journalism' lists the ways in which journalists can assist deliberation and politics in communities around the world. The chapter defines deliberation as a specific form of conversation that precedes and promotes decision-making and action by members of a community. The author recognises the difficulty of engaging in deliberation in communities that are divided by different interests, identities, backgrounds, resources and needs. She provides examples of strategies that journalists can use to encourage inclusive and productive deliberation in the face of community diversity.\ud
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The chapter introduces examples of types of deliberative journalism that have emerged around the globe. These include strategies that have been sometimes been labeled as public journalism, civic journalism, peace journalism, development journalism, citizen journalism, the street press, community journalism, environmental journalism, and social entrepreneurism. The chapter also includes models of journalism that have not yet been given any particular name. Although the book identifies problems surrounding the theory and practice of these forms of journalism, the author notes that this is to be expected. Most models of deliberative journalism are relatively new, with none being more than a few decades old. The author concludes that resolution of these problems will only occur incrementally
Romano Guardini, Der Gegensatz. Versuche zu einer Philosophie des Lebendig-Konkreten. Avec une postface de Hanna-Barbara Gerl. 1985
No full textBrito Emilio. Romano Guardini, Der Gegensatz. Versuche zu einer Philosophie des Lebendig-Konkreten. Avec une postface de Hanna-Barbara Gerl. 1985. In: Revue théologique de Louvain, 18ᵉ année, fasc. 4, 1987. p. 498
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