147 research outputs found
Totally implantable middle ear device for rehabilitation of sensorineural hearing loss: preliminary experience with the Esteem†, Envoy
No full textConclusion. According to the first series of implanted patients, Esteem 2† technology can be regarded as a safe and reliable system for hearing restoration in case of moderate to severe sensorineural hearing loss. Objectives. To assess the benefit deriving from implantation of a totally implantable middle ear device in subjects affected by moderate to severe sensorineural hearing loss, the Esteem 2† (Envoy Medical), as measured through pure tone audiometry testing carried out during the different postoperative fitting sessions. Patients and methods. Six patients have been operated on since July 2007. Selection was carried out via preoperative audiometric tests and thorough counseling, which considered information on previous experience with conventional hearing aids as well as each patient’s motivation to undergo a surgical application. Specific surgical training is needed to accommodate routine surgical steps along with less familiar steps, such as placement of cement material and overall fixation of the system. Results. The surgical procedure took a long time, but a reduced duration was recorded in the last procedure compared with the first one. The implantation process induced a deterioration in hearing thresholds, which fully recovered after activation of the device. A postoperative hearing gain could be measured in all three patients: in this regard, the perceived quality of sound was shown to be better than could be expected by the measurable hearing gain
Adding value to sheep farming through product development in Manni OÜ
No full textLammaste kasvatamine on Eestis viimastel aastatel muutunud populaarsemaks ning tegemist on
loomakasvatusharuga, mis on potentsiaalse tulutasemega. Lambakasvatajate ja lammaste arvu
suurenemine muudab lambakasvatuse ühiskonnas aktuaalseks teemaks. Lambakasvatusest saab
tulu teenida väga mitmel viisil. Ettevõtte Manni OÜ on jõudnud seisukohale, et lammaste
välismaale müük ei ole kõige tulusam ning oleks hea, kui leiaks lammaste turustamiseks paremaid
võimalusi.
Käesoleva bakalaureuse töö eesmärgiks on selgitada välja võimalused, kuidas anda
lambakasvatusele lisaväärtusi tootearenduse kaudu OÜ Mannis.
Antud bakalaureuse töö puhul kasutatakse kvalitatiivset uurimismeetodit, millest kasutatakse
intervjuud. Viiakse läbi intervjuud inimestega, kes on lambakasvatajad ning kes ka ise tegelevad
tootearendusega. Bakalaureusetöö koostamise käigus leitakse sobivad tootearenduse meetodid ja
võimalused, kuidas luua lisaväärtust ettevõttes Manni OÜ.
Autor leidis, et ettevõttele Manni OÜ oleksid sobilikeks lisaväärtuse loomise võimalusteks
lambaliha töötlemine, suguloomade müük, lammaste rentimine/müümine nii-öelda
muruniidukiteks ja lamba kasutamine taluturismis. Lisaväärtusi, mida tarbijad Manni OÜle
sobilike tootearenduse võimalustega saavad on palju.Sheep farming has gained popularity in Estonia over the past years and this livestock farming
branch has shown potential level of income. Due to the growing farmer and sheep numbers, sheep
farming has become a current affair. There are several ways of profiting from sheep farming.
Manni OÜ has determined, that export of sheep is not the most profitable one and is seeking for
better opportunities.
This bachelor's thesis aimed to determine opportunities for creating added value in sheep farming
through product development in Manni OÜ.
The author used qualitative research methods in the form of interviews with sheep farmers and
product developers. The author treated them as experts and has not indicated subject names in the
thesis. The bachelor's thesis determined suitable product development methods and opportunity
for added value creation in Manni OÜ.
The author has found, that suitable added value creation methods for Manni OÜ would be mutton
processing, sale of breeders, rental/sale of sheep for "lawn-mowers" and using sheep for farm
tourism. There are numerous added values for consumers from suitable product development
opportunities
A Right to be Forgotten in Public Registers?: CJ EU 9 March 2017, C-398/15 (Manni), ECLI:EU:C:2017:197)
No full textDutch Abstract: Annotatieartikel bij HVJEU Manni over toepassing van het (internet) vergeetrecht op faillissementsregisters. English Abstract: Case note article on CJEU Manni case regarding the possible application of the Right to be Forgotten to Public registers such as the Insolvency Register and Companies Register. Author also applies the Court's reasoning to Land Registry in the Netherlands
Een Vergeetrecht in Openbare Registers?: HvJ EU 9 maart 2017, C-398/15 (Manni), ECLI:EU:C:2017:197
No full textDutch Abstract: Annotatieartikel bij HVJEU Manni over toepassing van het (internet) vergeetrecht op faillissementsregisters. English Abstract: Case note article on CJEU Manni case regarding the possible application of the Right to be Forgotten to Public registers such as the Insolvency Register and Companies Register. Author also applies the Court's reasoning to Land Registry in the Netherlands
AUTHOR-CENTRED NOVELS: AUTOFICTION IN THE ENGLISH-SPEAKING WORLD AND BEYOND
No full textThe more autofiction is talked about, the more its identity and status are taken as a given. In English-language criticism especially, which has now jumped on the autofictional bandwagon, the need to define homegrown autofiction is conspicuously eluded, with scholars preferring to gesture towards an impenetrable undergrowth of imported theories whose relevance often remains uninterrogated. How can scholars of English-language literature conquer the consequent habit of merely engaging with autofiction as a “liminal position” (Worthington 2018), thus approaching it only in negative or hybrid terms? How does the growing corpus of autofiction in English serve to enhance the notion and foster its development, as well as opportunistically benefit from its heritage? Building on a wide range of autofictional texts by English-speaking authors, the aim of this work is to show how autofiction may be described a spectrum that ranges from works that mostly problematise genre to works that mostly problematise ontology. Cutting across these two polarities, moreover, is a tendency towards greater or lesser self-consciousness, the outcome of a move away from postmodernism that, while not dismissing its metafictional awareness of literary manipulation, repurposes it to reconstructive, sincerity-oriented ends. Finally, a preoccupation with the aesthetics of autofiction also paves the way for an engagement with the ethics of contemporary authorship and the status of truth, allowing for more nuanced debates on the specificity of each individual work of autofiction and its communicative function.Più si scrive di autofiction e più il suo status letterario e le sue peculiarità formali vengono dati per scontato. Nella critica accademica anglofona in particolare, dove il dibattito sull'autofiction ha ora assunto dimensioni considerevoli, la necessità di definire la forma assunta dal fenomeno quando coinvolge autori che scrivono in inglese viene abilmente elusa, dando prova di un atteggiamento di acritica sudditanza a una giungla di teorie di importazione la cui pertinenza è solo raramente messa in dubbio. Come potersi liberare, dunque, dall'abitudine di interpretare la letteratura autofinzionale anglofona come una "posizione liminale" (Worthington 2018), un approccio che porta a leggerla esclusivamente in termini negativi o ibridi? Come possiamo avvalerci del sempre più nutrito corpus di autofinzioni redatte in inglese per raffinare il concetto e favorirne lo sviluppo, oltre che per sfruttare opportunisticamente la tradizione che ha generato? Facendo leva su un'ampia gamma di testi autofinzionali di autori anglofoni, l'obiettivo del presente lavoro è quello di illustrare come l'autofiction possa essere descritta come uno spettro che abbraccia sia opere con un'enfasi sulla problematicità generica sia opere con un'enfasi su quella ontologica. A queste due polarità si aggiunge poi un altro asse che le attraversa trasversalmente e che misura il grado di autoconsapevolezza dell'opera stessa, legato a una presa di distanza dal postmodernismo che, pur senza abbandonarne la consapevolezza metafinzionale sulla manipolazione letteraria, la ricicla per obiettivi diversi, come una ricostruzione post-postmoderna o un'aspirazione di sincerità. Da ultimo, l'attenzione per l'estetica autofinzionale favorisce a sua volta un'analisi più approfondita dell'etica dell'autorialità e dello status della verità nel contesto contemporaneo, fornendo strumenti adatti a un esame dei tratti specifici di ciascuna opera autofinzionale presa individualmente e della sua funzione comunicativa
Character analysis of some Jurassic crinoids
No full textIn recent years several authors have proposed changes in cyrtocrinid crinoid systematics. The value of these different schemes is diminished because no author defines precisely the meaning of the characters used in his systematics. In this work the value of the various characters in systematics is assessed
Top-down HPLC-ESI–MS proteomic analysis of saliva of edentulous subjects evidenced high levels of cystatin A, cystatin B and SPRR3
No full textObjective This study aims to analyze the salivary peptidome/proteome of edentulous subject with respect to dentate control subjects. Design Unstimulated whole saliva, collected from 11 edentulous subjects (age 60–76 years) and 11 dentate age-matched control subjects, was immediately treated with 0.2% aqueous trifluoroacetic acid and the acidic soluble fraction analyzed by High Performace Liquid Chromatography-Mass Spectrometry. The relative abundance of the salivary peptides/proteins was determined by measuring the area of the High Performace Liquid Chromatography-Mass Spectrometry eXtracted Ion Current peaks which is linearly proportional to peptide/protein concentration under identical experimental conditions. Levels of salivary peptides/proteins in the two groups were compared by the nonparametric Mann-Whitney test to evidence statistically significant differences. Results Levels of cystatin A, S-glutathionylated, S-cystenylated, S-S dimer derivatives of cystatin B and S-glutathionylated derivative of SPRR3, were found significantly higher in edentulous subjects with respect to dentate controls. The major peptides and proteins typically deriving from salivary glands did not show any statistically significant differences. Conclusions Cystatin A, S-glutathionylated, S-cystenylated, S-S dimer derivatives of cystatin B and S-glutathionylated derivative of SPRR3, which are mainly of intracellular origin and represent the major constituents of the cornified cell envelope are a clue of inflammation of mucosal epithelia
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