1,721,235 research outputs found
Recensione a G. Baratta, M. Mayer i Olivé, M.F. Petraccia, F. Pettinari, M. Tramunto, Fabriano e le sue collezioni di antichità. La continuità di una tradizione di studi (Armarium 1), Roma: Scienze e Lettere, 2021
No full textRecensione a G. Baratta, M. Mayer i Olivé, M.F. Petraccia, F. Pettinari, M. Tramunto, Fabriano e le sue collezioni di antichità. La continuità di una tradizione di studi (Armarium 1), Roma: Scienze e Lettere, 202
Adults mammary stem cells in cow's milk: new perspectives and future challange
No full textThe discovery of the presence of stem cells and precursors with high regenerative potential in the mammary gland, hy- pothetically maintained throughout the course of the produc- tive life of the dairy cow sheds an interesting perspective in the research which is interested to clarify all physiological clues and possible solutions to increase or maintain longer the po- tential production of dairy cows during life span of lactation. In 2006, Connie Eaves’ lab in Vancouver (Stingl et ., 2006) [1] and Jane Visvader in Victoria (AU) (Schackleton et al., 2006) [2] have published the discovery of single mammary stem cells can repopulate the alveolar functional unit in mouse mam- mary gland. Later, bovine adult mammary stem cells have been functionally identified to regenerate alveoli that secrete milk [3,4]. Very recently it was described in human the pres- ence of breast stem cells in milk and this finding is now paving the way for investigation of the functions of these cells in the breastfed infant and the use of breast milk as a tool to under- stand the normal biology of the breast and its pathologies [5]. In dairy science these findings may be of great interest both from a scientific point of view and for possible future impacts on the economic chain of production of milk
Utilizzo di cellule staminali mammarie per il recupero funzionale della ghiandola mammaria nella vacca da latte
No full textEFFECT OF MELATONIN ON THE INVITRO SECRETION OF PROGESTERONE AND ESTRADIOL 17-BETA BY OVINE GRANULOSA-CELLS
No full textThis study was undertaken to determine the effect of melatonin on steroid hormone production by ovine granulosa and luteal cells in vitro. Granulosa and luteal cells from ovine ovaries were cultured for nine days either in D-MEM only or in the presence of melatonin (0.86, 8.6, 86 nmol/l), ovine luteinizing hormone (oLH, 2 mug/l) or a combination of both these hormones. Progesterone (P4) and estradiol 17beta (E2) were determined by validated RIAs. Melatonin stimulation began at either day 1 or day 5 of culture. Melatonin (0.86 nmol/l) significantly increased (p < 0.001) progesterone secretion by granulosa cells both when administered alone and when administered in combination with oLH; the more marked response was observed in the latter case, When the stimulation began at day 5, at a more advanced degree of differentiation of the cells, higher levels of P4 were observed. Higher concentrations of melatonin did not further increase progesterone production. Melatonin alone did not have a significant effect on the production of estradiol 17beta; neither did melatonin stimulate progesterone production in either long-term cultured luteal cells or in short-term (1-2 h) cultured luteal and granulosa cells. The results of this study document a direct effect of melatonin in stimulating granulosa cells to produce progesterone, a synergistic activity between melatonin and luteinizing hormone and a different ability of granulosa cells to secrete P4 depending on the degree of differentiation
Role of leptin on proliferation and differentiation of bovine and murine mammary epithelial cells
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