1,721,023 research outputs found
LMCT transition-based red-light photochemotherapy using a tumour-selective ferrocenyl iron( iii ) coumarin conjugate
No full textA bio-attuned ratiometric hydrogen sulfate ion selective receptor in aqueous solvent: structural proof of the H-bonded adduct
No full textA new cell permeable quinazoline based receptor (1) selectively senses HSO4 ions of nanomolar region in 0.1 M HEPES buffer (ethanol–water: 1/5, v/v) at biological pH over other competitive ions through the proton transfer followed by hydrogen bond formation and subsequent anion coordination to yield the [LHSO4]LH+$3H2O (2) ensemble, which has been crystallographically characterised to ensure the structure property relationship. This non-cytotoxic HSO4 ion selective biomarker has great potential to recognize the intercellular distribution of HSO4 ions in HeLa cells under fluorescence microscope
Amidinate based indium( iii ) monohalides and β-diketiminate stabilized In( ii )–In( ii ) bond: synthesis, crystal structure, and computational study
No full textSynthesis and computational aspects of Al( ii )–Al( ii ) and Ga( ii )–Ga( ii ) dihalides based on an amidinate scaffold
No full textSynthesis, crystal structure, and DFT study of amidinate compounds with Al( ii )–Al( ii ) and Ga( ii )–Ga( ii ) bonds as dihalide dimers
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
In‐vitro and In‐vivo Photocatalytic Cancer Therapy with Biocompatible Iridium(III) Photocatalysts
No full textAbstract Photocatalytic anticancer profile of a Ir III photocatalyst ( Ir3 ) with strong light absorption, high turnover frequency, and excellent biocompatibility is reported. Ir3 showed selective photo‐cytotoxicity against cisplatin‐ and sorafenib‐resistant cell lines while remaining dormant to normal cell lines in the dark. Ir3 exhibited excellent photo‐catalytic oxidation of cellular co‐enzyme, the reduced nicotinamide adenine dinucleotide phosphate (NADPH), and amino acids via a single electron transfer mechanism. The photo‐induced intracellular redox imbalance and change in mitochondrial membrane potential resulted in necrosis and apoptosis of cancer cells. Importantly, Ir3 exhibited high biocompatibility and photo‐catalytic anticancer efficiency as evident from in vivo zebrafish and mouse cancer models. To the best of our knowledge, Ir3 is the first Ir III based photocatalyst with such a high biocompatibility and photocatalytic anticancer therapeutic effect.National Natural Science Foundation of China https://doi.org/10.13039/501100001809Science and Technology Planning Project of Shenzhen Municipality https://doi.org/10.13039/501100013093Fundamental Research Funds for Central Universities of the Central South University https://doi.org/10.13039/501100012476National Science Foundation https://doi.org/10.13039/10000000
- …
