1,720,999 research outputs found
Early palliative and supportive care in hematology wards.
No full textEarly palliative and supportive care in hematology ward
Education of early palliative care specialists among hematologists and oncologists to address patients’ rather than physicians’ rights
No full textEarly Palliative Care: A Necessary Intervention for Patients Ineligibile to Approved Potentially Life-saving CAR T-cell Therapy
No full textCOVID-19 Pandemic and Cancer: The Importance of Early Palliative Care
Full text linkIn terms of clinical and ethical situations, this narrative compares the COVID-19 pandemic to the cancer endemic and shares information that may be helpful to improve the management of both future pandemics and cancer care
Orally administered Panax notoginseng influence on rat spontaneous behaviour
No full textPanax notoginseng root is highly prized in China for its supposed hemorheological properties. Its behavioural effects are still not scientifically investigated; therefore, our preliminary study aim is to evaluate the influence of this phyto-drug on rats spontaneous behaviour. High quality P. notoginseng root dry extract has been orally administered through gastric tube for 10 days in two doses (43 and 86 mg/kg in a volume of 5 ml/kg per day) and its effects on locomotion, emotional reactivity and nutrition have been evaluated in different groups of Wistar rats (ten per group) versus animals treated with 5 ml/kg per day of saline. Actimeter test, open field test and microstructural analysis of unconditioned behaviour were carried out. The data were processed by ANOVA-test followed by the Student's one-tail t-test and a 0.05 significance level was chosen for all statistical tests. A significant increase in spontaneous motility being not associated to an increase in grooming episodes duration and number was found in all tests (P<0.05). Feeding behaviour appeared not to be affected by the treatment. Observed effects did not seem dose-related. Reduction of grooming episodes duration and number and increase of inner crossings in open field suggested that notoginsenoides can modulate emotional responses in rats
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Independent research on cancer pain management in the setting of early palliative care: A flywheel to counteract general opioid misuse and abuse
Full text linkThe increased recognition of the high prevalence and important burden of cancer pain and the documentation of a large proportion of patients receiving inadequate analgesic treatment should have reinforced the need for evidence-based recommendations. The World health Organization (WHO) guidelines on cancer pain management—or palliative care—are traditionally based on a sequential, three-step, analgesic ladder according to pain intensity: nonopioids (paracetamol or nonsteroidal anti-inflammatory drugs) to mild pain in step I; weak opioids (eg, codeine or tramadol) to mild-moderate pain in step II; and strong opioids to moderate-severe pain in step. III. Despite the widespread use of this ladder, unrelieved pain continues to be a substantial concern in one third of patients with either solid or hematologic malignancies. The sequential WHO analgesic ladder, and in particular, the usefulness of step II opioids have been questioned but there are no universally used guidelines for the treatment of pain in patients with advanced cancer and not all guideline recommendations are evidence-based. The American Society of Clinical Oncology and the European Society of Medical Oncology have recommended the implementation of early palliative care (EPC), which is a novel model of care, consisting of delivering dedicated palliative service concurrent with active treatment as early as possible in the cancer disease trajectory. Improvement in cancer pain management is one of the several important positive effects following EPC interventions. Independent well-designed research studies on pharmacological interventions on cancer pain, especially in the EPC setting are warranted and may contribute to spur research initiatives to investigate the poorly addressed issues of pain management in non cancer patients
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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