642 research outputs found

    Diffusione di Extended-Spectrum-ß-Lattamasi di tipo CTX-M in isolati clinici di E. coli provenienti da strutture di lungodegenza e riabilitazione geriatriche del Nord Italia

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    During the period March 2003 – May 2004 at the Laboratory of Clinical Microbiology “Redaelli” LTCRF in Milan, Italy, a total of 529 E. coli, obtained from inpatients of 3 different Long Term Care Rehabilitation Facilities (LTCRFs) in Northern Italy, were processed and 77 ESßLs producers (14.5%) were identified by Vitek System. The results were confirmed by double-disk synergy test with tazobactam (TZP). 61/77 isolates were characterized by higher levels of resistance to cefotaxime (CTX) than to ceftazidime (CAZ). (ß-lactamase production was investigated by analytical isoelectric focusing (IEF) coupled with a bioassay and showed multiple (ß-lactamase bands including one enzyme with pI 8.4 that, in a bioassay, was more active on CTX,ATM than on CAZ. The presence of (ß-lactamase genes was investigated by colony blot hybridization and by PCR amplification of blaTEM, blaSHV and blaCTX-M alleles. 43/61 isolates produced both TEM-1 and CTX-M-type enzymes, 14/61 expressed only CTX-M-type while in 4 cases were found blaCTX-M, blaTEM and blaSHV genes.The remainders (16/77), characterized by high levels of resistance to both CTX and CAZ, produced TEM-1 and SHV-5 enzymes (1/16) and TEM type ESßLs (15/16). Conjugation experiments, performed in liquid medium, confermed that the ESßLs determinants were transferable. Pulsed-field gel electrophoresis profiles of genomic DNA, digested with NotI, were analysed and revealed clonal heterogeneity. Our work confirms the emergence of CTX-M-type enzymes and their spread in Northern Italy also in longterm care and rehabilitation facilities that may be an important reservoir of ES?L producing E. coli

    Natural risk assessment and managment

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    "Natural risk assessment and managment" is a chapter of the "Handbook on Urban Sustainability", edited by Nolberto Munier. A book which addresses the sustainable development of a city. In particular Michela Tiboni deals with a subject rarely seen in the technical literature: Risk management. It refers to risks related with land uses, and as the author rightly states its aim is to reduce danger for human beings and the environment. Some projects are built on terrains that have characteristics that make then unsuitable for that kind of project. Others alter the natural flow of water during storms, paving the way to floods, and cave ins. Both can generate action-reaction response. This Chapter presents the necessary guidelines to evaluate a risk involved in the construction of a project. This is something that has to be carefully considered to avoid future consequences, which can turn to be catastrophic. Remember, most human activities modify the environment, and it is then necessary to evaluate the consequences of such actions

    ACERCA DEL REALISMO PERSPECTIVISTA DE MICHELA MASSIMI

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    In Perspectival Realism (2022), Michela Massimi seeks to make compatible two positions usually presented as irreconcilable: pluralistic perspectivism and scientific realism. It is shown that the strategy adopted by the author in pursuit of the proposed objective is unsuccessful. However, this does not imply that both positions are decidedly incompatible. We put forward an alternative proposal that allows scientific realism and pluralism to be coherently reconciled. En Perspectival Realism (2022), Michela Massimi procura compatibilizar dos posiciones que, usualmente, se presentan como irreconciliables: el perspectivismo pluralista y el realismo científico. Se muestra que la estrategia adoptada por la autora en pos del objetivo propuesto resulta fallida. Sin embargo, ello no implica que ambas posiciones sean decididamente incompatibles. Se adelanta una propuesta alternativa que permite conciliar de manera coherente el realismo y el pluralismo científicos.   DOI: https://doi.org/10.29327/2194248.5.3-7

    Interview with Michela Williams by Kaia Godsey, June 14, 2023

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    Michela Williams explores her work and journey to Black to Earth, and shares the role her family played in her pursuing this community career. She shares moments that encouraged her, such as memories of her grandma and meals shared with relatives. Michela also talks about the role history plays in getting Black folks involved in food and outdoor work. She ends her interview with the notion of networks and explaining the role they will play in the future

    The beginnings of pPhilosophy in Greece

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    How can we talk about the beginnings of philosophy today? How can we avoid the conventional opposition of mythology and the dawn of reason and instead explore the multiple styles of thought that emerged between them? In this acclaimed book, available in English for the first time, Maria Michela Sassi reconstructs the intellectual world of the early Greek “Presocratics” to provide a richer understanding of the roots of what used to be called “the Greek miracle.” The beginnings of the long process leading to philosophy were characterized by intellectual diversity and geographic polycentrism. In the sixth and fifth centuries BC, between the Asian shores of Ionia and the Greek city-states of southern Italy, thinkers started to reflect on the cosmic order, elaborate doctrines on the soul, write in solemn Homeric meter, or, later, abandon poetry for an assertive prose. And yet the Presocratics, whether the Milesian natural thinkers, the rhapsode Xenophanes, the mathematician and “shaman” Pythagoras, the naturalist and seer Empedocles, the oracular Heraclitus, or the inspired Parmenides, all shared an approach to critical thinking that, by questioning traditional viewpoints, revolutionized knowledge. A unique study that explores the full range of early Greek thinkers in the context of their worlds, the book also features a new introduction to the English edition in which the author discusses the latest scholarship on the subject

    Girolamo Fabrici d'Acquapendente, De locutione, De brutorum loquela. Edizione, traduzione e commento a cura di Stefano Gensini e Michela Tardella

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    Questo libro offre la prima edizione moderna di tue trattati dell'anatomista e chirurgo Girolamo Fabrici d'Acquapendente (1533-1619), il De locutione (prima ed. 1601), e il De brutorum loquela (1603). Profondamente radicato nella tradizione aristotelica dell'Università di Padova, Fabrici propose con questi trattati la prima analisi delle basi biologiche del linguaggio (anche in chiave comparativa) della Modernità. I due trattati sono stati oggetto, dopo la morte dell'autore, di svariate ristampe fino al medio Settecento, che hanno però gravi limiti editoriali. I testi sono stati pertanto emendati dal punto di vista linguistico, corretti dal punto di vista redazionale, commentati analiticamente in chiave storica e filosofico-linguistica. In particolare, le sezioni della 'Introduzione' scritte da S. Gensini e il commento da lui curato del De brutorum loquela insistono sulla originalità delle posizioni di Fabrici a proposito sia delle capacità cognitive degli animali non umani sia dei loro linguaggi. Basandosi sulle fonti antiche, in particolare sui trattati biologici di Aristotele, i Moralia di Plutarco e il De Abstinentia di Porfirio, si sostiene che Fabrici riuscì a presentare il linguaggio animale nei termini di un comportamento complesso, autonomo da quello umano, dotato di propri caratteri specie-specifici sia dal punto di vista anatomico che da quello dell'espressione dei contenuti psicologici.This book gives the first modern edition of two important treatises on language and animal language written by the Italian anatomist and surgeon Girolamo Fabrici of Acquapendente (1533-1619), dating back respectively to 1601 and 1603. Deeply rooted into the aristotelian tradition of the Padua University, these treatises represent the first investigation of the biological foundations of language (also from a comparative viewpoint) in the first Modern Age. After Fabrici's death the two writings were often reprinted up the Midth 18th century, but in a very uncorrect editorial form. The texts have been fully emendated for the present edition, and carefully commented from both a historical and a philosophical-linguistic viewpoint. Both the sections of the "Introduction" by Gensini and the commented edition of the "De brutorum loquela" by the same author insist on Fabrici's original position regarding cognitive capabilities and genuine 'language(s)' (loquela) typical of non-human animals. Drawing on ancient sources such as Aristotle's biological writings, Plutarch's Moralia and Porphyry's De Abstinentia, Fabrici was able to depict animal language(s) in terms of complex behaviors, grounded on species-specific anatomical characters and psychological powers

    Extrapolation and rational approximation: the works of the main contributors

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    This book paints a fresco of the field of extrapolation and rational approximation over the last several centuries to the present through the works of their primary contributors. It can serve as an introduction to the topics covered, including extrapolation methods, Padé approximation, orthogonal polynomials, continued fractions, Lanczos-type methods, etc.; it also provides in depth discussion of the many links between these subjects. A highlight of this book is the presentation of the human side of the fields discussed via personal testimonies from contemporary researchers, their anecdotes, and their exclusive remembrances of some of the “actors.” This book shows how research in this domain started and evolved. Biographies of other scholars encountered have also been included. An important branch of mathematics is described in its historical context, opening the way to new developments. After a mathematical introduction, the book contains a precise description of the mathematical landscape of these fields spanning from the 19th century to the first part of the 20th. After an analysis of the works produced after that period (in particular those of Richardson, Aitken, Shanks, Wynn, and others), the most recent developments and applications are reviewed. Claude Brezinski is professor emeritus of mathematics at the University of Lille (France), where he has been head of the Laboratory of Numerical Analysis and Optimization for 30 years. He was the advisor of 60 doctoral students. Prof. Brezinski is founder and Editor-in-Chief of the Numerical Algorithms journal and author of over 240 papers and several books. Michela Redivo-Zaglia is professor of numerical analysis at the University of Padua (Italy). She has been vice-director of the Department of Mathematics for three years. She is a member of the Editorial Board of several journals. She published software packages, 7 scientific and didactic books, and about 80 papers. She was the organizer of many international congresses, and an invited speaker at several ones

    Interpretare un processo di qualità [Interpreting a Process of Quality]

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    Il saggio presenta elementi interpretativi della pubblicazione "Sudtirolo Architettura/Südtirol Architektur“, in cui è confluito un complesso lavoro di ricerca condotto per alcuni anni dall'autrice nella Provincia Autonoma di Bolzano. I contenuti sono condivisi in occasione di un confronto sulle prospettive di applicazione dello standard NZEB nell'up-cycling degli edifici*. Il punto di partenza è la normativa CasaClima, che vede il territorio alpino leader per quanto riguarda gli aspetti energetici delle costruzioni, ma, piuttosto che concentrarsi sugli aspetti tecnici riguardanti le soluzioni costruttive ad alta efficienza adottate, ampiamente trattati nella letteratura del settore, l'obiettivo del lavoro è entrare nel merito delle connessioni tra architettura e condizioni culturali del territorio, che consentano di comprendere le ragioni dell'eccellenza nel settore delle costruzioni. In questi termini, il saggio intende mettere a fuoco le peculiarità di una ricerca di processo, che per prima, rispetto ad altri studi, affronta il tema di un modello sudtirolese di gestione del territorio, dove si riconosce un forte nesso tra abilità tecniche e sviluppo sociale. Entra nel cuore della ricerca che riguarda: il nodo cruciale della presunta neutralità della tecnologia rispetto al territorio in cui è utilizzata; il rapporto tra innovazione e architettura; il ruolo di quest'ultima nella società. La tesi che si vuole dimostrare nella ricerca è che il Sudtirolo si presenta come un caso unico nel panorama italiano che deve essere interpretato al di là di quanto riguarda specificatamente gli aspetti tecnici; come è infatti documentato nel lavoro, l'eccellenza dei risultati nell'ambito dell'architettura e delle tecnologie applicate all'edilizia deriva dalle differenze culturali di queste zone rispetto al resto del Paese, che si concretizzano a vari livelli in un più ampio sviluppo della partecipazione delle persone alla vita della collettività. * Il lavoro riporta i contenuti della relazione di Michela Toni “Presentazione di volumi di autori del Dipartimento di Architettura – Unife su temi inerenti al Convegno. Sudtirolo Architettura – Le differenze di un territorio attraverso un itinerario tra costruzioni realizzate nel rispetto della normativa CasaClima/ Südtirol Achitektur – Die Eigenheiten eines Gebietes am Beispiel von Gebäuden mit KlimaHaus Standard ”. La presentazione si è svolta il 4 luglio 2016 nel Pre-Convegno che ha anticipato il Convegno SITdA, svolto presso il Dipartimento di Architettura dell'Università di Ferrara nelle giornate del 4 e del 5 luglio 2016, Nuove prospettive di efficienza energetica e qualità ambientale per il patrimonio edilizio esistente. Riflessioni e strumenti per il raggiungimento degli standard NZEB nell'up-cycling degli edifici.This essay focuses on interpretative issues of the "South Tyrol Architecture/Südtirol Architektur" publication, in which a multiannual research work conducted by the author in the Autonomous Province of Bozen-Bolzano has merged. The contents are shared during a comparison on the perspectives of the NZEB standard application in the up-cycling of buildings*. The starting point is the CasaClima standard, which sees the Alpine region as a leader in dealing with the energy aspects of the buildings. However, rather than focusing on the technical issues associated with the high efficiency construction solutions adopted (widely discussed in the sector literature), the work aims at entering into the connections between architecture and cultural conditions of the territory, which allow to understand the reasons for excellence in the construction sector. In these terms, the essay focuses on the peculiarities of a first-ever research addressing the theme of a South Tyrolean model of land management, where a strong link between technical skills and social development is recognized. It enters into the very heart of the research, i.e., the crucial node of the assumed neutrality of technology with respect to the territory in which it is used; the relationship between innovation and architecture; and the role of the latter in society. The assumption to be demonstrated in the research is that South Tyrol is a unique case in the Italian landscape to be understood beyond what specifically concerns the technical aspects. As documented in this work, the excellence of the results in the field of architecture and technologies applied to construction comes from the cultural differences of these areas compared to the rest of the country, which materialize in a wider development of people's participation in the life of the community. * The work summarizes a presentation by Michela Toni titled “Presentazione di volumi di autori del Dipartimento di Architettura, Unife” about the topics discussed at the Südtirol Achitektur’s conference “Le differenze di un territorio attraverso un itinerario tra costruzioni realizzate nel rispetto della normativa CasaClima/ Südtirol Achitektur – Die Eigenheiten eines Gebietes am Beispiel von Gebäuden mit KlimaHaus Standard ”. Toni’s presentation was given on July 4, 2016 during the workshop prior to the SITdA conference (Department of Architecture, University of Ferrara, July 4 & 5, 2016, “Nuove prospettive di efficienza energetica e qualità ambientale per il patrimonio edilizio esistente. Riflessioni e strumenti per il raggiungimento degli standard NZEB nell'up-cycling degli edifici”)
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