1,720,971 research outputs found
CD3 and CD20 Expressions and Infiltrating Patterns in Salivary Gland Tumors
No full textTumor-infiltrating lymphocytes (TILs) represent a subset of immunological constituents within the tumor microenvironment that can influence cancer growth. We retrospectively evaluate the density and pattern of CD3 and CD20 expression in salivary gland tumors and their relation to clinical pathologic parameters. A total of 44 formalin-fixed paraffin-embedded blocks of salivary gland tumors were included. These tumors were stained immunohistochemically with CD3 and CD20. The chi-square test was used to relate immune scoring, intensity, and clinical pathological parameters to different salivary tumors. p-value < 0.05 was considered statistically significant. The intra-tumoral CD3 infiltrating count was high and diffused in (71.4%) of pleomorphic adenomas (PAs) followed by mucoepidermoid carcinomas (MECs) (66.7%). At the same time, adenoid cystic carcinomas (AdCCs) exhibited significantly low infiltration (71.4%) (p = 0.046). The three types of tumors exhibited high tumor-infiltrating counts diffused in peripheral areas with significant differences between malignant tumors (p = 0.047). The intra-tumoral CD20 infiltrating count significantly differed among the tumors (p = 0.002); it was low in all PAs and AdCCs, while MECs showed an equal percentage of expression. However, in the peripheral area, PAs and MECs exhibited significantly (p = 0.007) high infiltrating counts (69.2% and 84.6), and the lowest infiltrating count was predominantly found for AdCCs. The two markers had a significant positive correlation between the mean of CD3 in the intra-tumoral and peripheral regions and CD20 in the peripheral zone across the total samples. In conclusion, the density of CD3 expression is notably higher than CD20 across tumor types. PAs and MECs showed high-density scores, while AdCCs were characterized by low scores. TIL expression was found to be significantly associated with patients’ outcomes in the intra-tumoral area
Prevalence of oral mucosal changes in type 2 diabetic patients attending diabetes mellitus center in Sulaimani city
Full text linkObjective: Find the prevalence of possible changes seen in the oral mucosa of type 2 diabetes mellitus patients.Methods: Three hundred type 2 DM patients included in this study after taking their medical history and glycemic control level.Patients were asked for symptoms of dry mouth, burning sensation, pain and paresthesia and they were subjected to full oral mucosalexamination.Results: Most patients had one or more subjective oral complain (83%). The predominant symptom was the feeling of dry mouth(80%) with no sex difference (P= 0.772). The mucosal pain reported in (12.7%) and significantly in males (P= 0.000). Gingivalredness reported in (33.3%) and paresthesia in (8%). Nine (3%) patients had white buccal patches and six of them revealed lichenoiddrug reaction. Dry mouth and oral burning sensation were shown to be unrelated to the glycemic control. Gingival redness was themost common lesion and correlated with poor glycemic control. Tongue was the second most commonly affected site in both sexes;however, the type of changes was sex and age-dependent. Denture stomatitis was seen in 4% and more frequent in females and inold age patients but did not relate to glycemic status. Lichenoid drug reaction was more prevalent among patients with poor glycemiccontrol (6.3%) and who were above 50 years old. Buccal mucosal white patches were related to the glycemic control (P = 0.014).Conclusions: Dry mouth was the most common complaints of a diabetic patient in all levels of glycemic control. Gingival rednesswas frequent in diabetic patients and correlated with poor glycemic control. Buccal white patches were more prevalent in patientswith poor glycemic control and who were above 50 years old
The Impact of Cerebral Palsy on The Health, Functions, and Habits of The Oral Cavity among Children in Sulaimani City
Full text linkObjective: Identify the impact of Cerebral Palsy (CP) on oral health, function, and habits.Methods: A thorough examination of the oral mucosa in one hundred CP children was carried out after obtaining detailed medical anddental histories. ANOVA and Chi-square tests were used to analyze the data, and p-value ≤ 0.05 considered significant.Results: CP children predominated by males (58%) and spastic type (64%). 27% of them visited a dentist (44.5% pain), 45% performedtooth brushing (57.8% need help), 31.8% mixed CP type only eat liquid diet. CP children had a burning tongue (11%) and halitosis(32%). Dry mouth and cracked lips were the minor symptoms. Functional limitations in chewing (34%), speech (59%), swallowing(37%) were also recorded. The majority of CP children had several oral disorders and habits including: saliva drooling (59%), mouthbreathing (45%), thumb sucking (32%) and teeth bruxism (31%). Lip and tongue sucking was significantly more in ataxic type (p =0.04). Changes in the tongue mucosa were the predominant findings (24%).Conclusions: The majority of CP children did not perform brushing, and few of them visited the dentist. The tongue mucosa was themost affected site. CP patients had multiple oral habits and orofacial functional difficulties predominated by drooling and mouthbreathing
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
- …
