1,720,971 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
ǂThe ǂrole of SOX2 and SOX9 genes and miR-21 in phenotypical characteristics of astrocytes derived from pluripotent NT2/D1 cells
No full textAstrociti su glavne homeostatske ćelije centralnog nervnog sistema (CNS), sa jedinstvenom sposobnošću da se aktiviraju u odgovoru na različita patološka stanja CNS-a. Poznato je da tokom procesa aktivacije ponovo stiču određene osobine astrocitnih prekursora, uključujući ponovnu ekspresiju regulatornih proteina SOX2 i SOX9. Iako su uloge SOX2 i SOX9 u gliogenezi poznate, njihove funkcije u zrelim astrocitima nisu u potpunosti razjašnjene. MikroRNK (miRNK) predstavljaju bitne regulatore različitih funkcija astrocita, pri čemu miR-21 ima značajnu ulogu u reaktivnoj astrogliozi. Međutim, njena uloga u drugoj značajnoj fenotipskoj promeni astrocita, senescenciji, nije poznata. Primenom lentiviralne transdukcije, imunofluorescencije i Western blot-a na astrocitima poreklom od NT2/D1 ćelija (NT2/A) ispitane su uloge SOX2, SOX9 i miR-21 u fenotipskim osobinama astrocita, sa fokusom na procese aktivacije i senescencije. Rezultati su pokazali da SOX2 povećava proliferativni kapacitet NT2/A, dok SOX9 povećava migratorni kapacitet. Takodje, pokazano je da SOX9 povećava ekspresiju NFIA i glutamatnog transportera GLAST kao i da dovodi do povećanja kapaciteta za preuzimanje vanćelijskog glutamata u zrelim astrocitima. Sa druge strane, utišavanje miR-21 smanjuje proliferaciju astrocita i potencijalno pomaže njihov ulazak u senescenciju. Naši rezultati pokazuju da SOX2, SOX9 i miR-21 ostvaruju bitne uloge u procesima aktivacije i senescencije astrocita. Razumevanje njihovog uticaja na fenotipske karakteristike astrocita vezanih za aktivaciju i senescenciju otvara mogućnost za njihovu modulaciju koja bi potencijalno mogla doprineti razvoju novih terapeutskih strategija za regeneraciju tkiva i oporavak CNS-a.Astrocytes are the primary homeostatic cells of the central nervous system (CNS), with a unique ability to reactivate in response to various pathological disorders of the CNS. During the reactivation process, they reacquire certain characteristics of astrocytic precursors, including re-expression of the transcription factors SOX2 and SOX9. While the roles of SOX2 and SOX9 in gliogenesis are well known, their functions in mature astrocytes remain incompletely understood. MicroRNAs (miRNAs) are key regulators of various astrocytic functions, with miR-21 playing a significant role in reactive astrogliosis. However, its role in another major phenotypic change in astrocytes, senescence, is unknown. Lentiviral transduction, immunofluorescence, and Western blot analysis were employed to investigate the roles of SOX2, SOX9, and miR-21 in the phenotypic properties of astrocytes derived from NT2/D1 cells (NT2/A), with the focus on the processes of reactivation and senescence. Our results showed that SOX2 increases the proliferative capacity of NT2/A, while SOX9 increases their migratory capacity. SOX9 also increases the expression of NFIA and the glutamate transporter GLAST, as well as the capacity for extracellular glutamate uptake in mature astrocytes. Silencing miR-21 reduces astrocyte proliferation and potentially promotes their senescence. Our findings indicate that SOX2, SOX9, and miR-21 play critical roles in the processes of astrocyte reactivation and senescence. Understanding the influence of these factors on astrocyte phenotypic characteristics related to reactivation and senescence opens the possibility for their modulation, which could potentially contribute to the development of novel therapeutic strategies for tissue regeneration and CNS recovery
The role of SOX2 and SOX9 genes and miR-21 in phenotypical characteristics of astrocytes derived from pluripotent NT2/D1 cells
No full textAstrociti su glavne homeostatske ćelije centralnog nervnog sistema (CNS), sa jedinstvenom
sposobnošću da se aktiviraju u odgovoru na različita patološka stanja CNS-a. Poznato je da tokom
procesa aktivacije ponovo stiču određene osobine astrocitnih prekursora, uključujući ponovnu
ekspresiju regulatornih proteina SOX2 i SOX9. Iako su uloge SOX2 i SOX9 u gliogenezi poznate,
njihove funkcije u zrelim astrocitima nisu u potpunosti razjašnjene. MikroRNK (miRNK)
predstavljaju bitne regulatore različitih funkcija astrocita, pri čemu miR-21 ima značajnu ulogu u
reaktivnoj astrogliozi. Međutim, njena uloga u drugoj značajnoj fenotipskoj promeni astrocita,
senescenciji, nije poznata. Primenom lentiviralne transdukcije, imunofluorescencije i Western blot-a
na astrocitima poreklom od NT2/D1 ćelija (NT2/A) ispitane su uloge SOX2, SOX9 i miR-21 u
fenotipskim osobinama astrocita, sa fokusom na procese aktivacije i senescencije. Rezultati su
pokazali da SOX2 povećava proliferativni kapacitet NT2/A, dok SOX9 povećava migratorni
kapacitet. Takodje, pokazano je da SOX9 povećava ekspresiju NFIA i glutamatnog transportera
GLAST kao i da dovodi do povećanja kapaciteta za preuzimanje vanćelijskog glutamata u zrelim
astrocitima. Sa druge strane, utišavanje miR-21 smanjuje proliferaciju astrocita i potencijalno pomaže
njihov ulazak u senescenciju. Naši rezultati pokazuju da SOX2, SOX9 i miR-21 ostvaruju bitne uloge
u procesima aktivacije i senescencije astrocita. Razumevanje njihovog uticaja na fenotipske
karakteristike astrocita vezanih za aktivaciju i senescenciju otvara mogućnost za njihovu modulaciju
koja bi potencijalno mogla doprineti razvoju novih terapeutskih strategija za regeneraciju tkiva i
oporavak CNS-a.Astrocytes are the primary homeostatic cells of the central nervous system (CNS), with a
unique ability to reactivate in response to various pathological disorders of the CNS. During the
reactivation process, they reacquire certain characteristics of astrocytic precursors, including re-
expression of the transcription factors SOX2 and SOX9. While the roles of SOX2 and SOX9 in
gliogenesis are well known, their functions in mature astrocytes remain incompletely understood.
MicroRNAs (miRNAs) are key regulators of various astrocytic functions, with miR-21 playing a
significant role in reactive astrogliosis. However, its role in another major phenotypic change in
astrocytes, senescence, is unknown. Lentiviral transduction, immunofluorescence, and Western blot
analysis were employed to investigate the roles of SOX2, SOX9, and miR-21 in the phenotypic
properties of astrocytes derived from NT2/D1 cells (NT2/A), with the focus on the processes of
reactivation and senescence. Our results showed that SOX2 increases the proliferative capacity of
NT2/A, while SOX9 increases their migratory capacity. SOX9 also increases the expression of NFIA
and the glutamate transporter GLAST, as well as the capacity for extracellular glutamate uptake in
mature astrocytes. Silencing miR-21 reduces astrocyte proliferation and potentially promotes their
senescence. Our findings indicate that SOX2, SOX9, and miR-21 play critical roles in the processes
of astrocyte reactivation and senescence. Understanding the influence of these factors on astrocyte
phenotypic characteristics related to reactivation and senescence opens the possibility for their
modulation, which could potentially contribute to the development of novel therapeutic strategies for
tissue regeneration and CNS recovery
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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