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Hypertensive Heart Failure: Sprinting to the Finish Line to Prevent End-Organ Damage Preface
No full textRegional myocardial blood flow redistribution as a cause of postprandial angina pectoris
No full textBackground - Postprandial angina pectoris has been recognized for more than two centuries and can be identified in up to 10% of patients with chronic ischemic heart disease, Redistribution of myocardial blood flow, from a region supplied by a severely stenotic coronary artery to those supplied by less diseased or normal vessels, is a potential mechanism of postprandial angina. Methods and Results - To test this hypothesis, we have determined the effects of a standard liquid meal on whole heart and regional myocardial blood flow, measured by means of dynamic positron emission tomography (PET) with O-15-labeled water in 14 patients with a reproducible history of postprandial angina and 7 matched control subjects, The standard liquid meal precipitated angina pectoris in all patients, Baseline whole heart blood flow was similar and increased normally after the meal in patients (0.97 +/- 0.14 to 1.14 +/- 0.25 mL.min(-1).g(-1), P < .04) as in control subjects (0.92 +/- 0.12 to 1.02 +/- 0.13 mL.min(-1).g(-1), P < .02). In contrast, the coefficient of variation of blood flow increased significantly after the standard Liquid meal in patients (34 +/- 9%, P < .05 versus baseline) but not in control subjects (17 +/- 7%, P = NS versus baseline). in patients, analysis of regional myocardial blood flow demonstrated decreased myocardial blood flow in territories supplied by stenotic arteries (1.01 +/- 0.35 to 0.76 +/- 0.27 mL.min(-1).g(-1), P < .03), but there was an increase in blood flow in territories supplied by normal arteries (0.89 +/- 0.16 to 1.34 +/- 0.25 mL.min(-1). g(-1), P < .001) after the meal. Conclusions - The standard liquid meal induced angina pectoris in patients with coronary artery disease. Although whole heart blood flow increased appropriately for the greater cardiac work, there was a redistribution of regional blood flow from territories supplied by severely stenosed coronary arteries to those supplied by less diseased or normal arteries. This redistribution may be the cause of myocardial ischemia in postprandial angina
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No full textCardiac and skeletal muscle insulin resistance in patients with coronary heart disease - A study with positron emission tomography
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GH deficiency in mild-to-moderate chronic heart failure is associated to worse clinical status, cardiopulmonary performance, and LV remodeling
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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