3,209 research outputs found
Genetic Assimilation and Canalisation in the Baldwin Effect
Get PDFThe Baldwin Effect indicates that individually learned behaviours acquired during an organism’s lifetime can influence the evolutionary path taken by a population, without any direct Lamarckian transfer of traits from phenotype to genotype. Several computational studies modelling this effect have included complications that restrict its applicability. Here we present a simplified model that is used to reveal the essential mechanisms and highlight several conceptual issues that have not been clearly defined in prior literature. In particular, we suggest that canalisation and genetic assimilation, often conflated in previous studies, are separate concepts and the former is actually not required for non-heritable phenotypic variation to guide genetic variation. Additionally, learning, often considered to be essential for the Baldwin Effect, can be replaced with a more general phenotypic plasticity model. These simplifications potentially permit the Baldwin Effect to operate in much more general circumstances
The network is sacred: Tim Berners-Lee, digital religion and Unitarianism
No full textIn the fledgling field of Digital Religion much deliberation has been given to how technology and digital culture has impacted on religion. Less attention however, has been in the other direction, namely how religion itself might have influenced technology and the internet. Here, Jon Baldwin considers Tim Berners-Lee, Unitarianism, and the internet
Keynote: Jon Gertner
No full textThe symposium will start on the evening of April 16 with a keynote address by Jon Gertner. Jon is a journalist, historian, and feature writer for The New York Times Magazine
as well as the author of the NYTimes bestseller, The Idea Factory. His address will focus on the issue of intellectual property and the ethical questions around the huge amount of human-generated content that large language models use as they are developed
Jon Mirande eta ironia
No full textLa ironía es un elemento que ha ido siempre unido a la poesía, y especialmente a la poesía moderna.Tras un pequeño repaso a esta en diferentes épocas, se pasa a describir las tres diferentes ironías de Jon Mirande: la intelectual, la social y la filosófica. Todo ello acompañado de ejemplosIrony is an element that has always been united to poetry, and especially to modern poetry. After a small revision of irony in different eras, the author then describes the three different ironies of Jon Mirande: intellectual, social and philosophical irony. All this illustrated with example
Time to reconsider monoamine oxidase inhibitors for obsessive compulsive disorder?: a case series using phenelzine
No full textPurpose/Background Despite the availability of a range of efficacious evidence-based treatments for obsessive-compulsive disorder (OCD), not all patients experience sufficient benefit or are able to tolerate them in practice. Monoamine oxidase inhibitors (MAOIs) show efficacy in the treatment of depression and certain anxiety disorders (such as social anxiety disorder). Methods/Procedures We survey the evidence base from case reports, and clinical trials, regarding use of MAOIs in OCD. We then present new data from a case series collected in routine clinical practice in a specialist clinical service. Findings/Results In 9 treatment-resistant patients whose OCD had not improved with at least 2 standard treatment trials, 3 had marked clinical improvement (>35% improvement on YBOCS) on phenelzine, 3 had some improvement (15-34.9%), and 3 showed minimal or no improvement (<15%). In the 3 patients who experienced minimal/no improvement, 2 had discontinued early because of lack of tolerability, and the other patient discontinued after 4 weeks because of perceived lack of symptom benefit. Implications/Conclusions We suggest that (1) MAOIs in treatment-resistant OCD require appropriate research scrutiny in large-scale randomized controlled trials; and (2) MAOIs merit consideration as a treatment option in individual cases of OCD, particularly in specialist settings where first-line interventions have proven inadequate to manage severe symptoms.</p
Jon Pineda, 32nd Annual ODU Literary Festival
No full textJon Pineda is the author of The Translator\u27s Diary, winner of the Green Rose Prize for Poetry, and BIrthmark, winner of the Crab Orchard Award Series in Poetry Open Competition. His memoir, Sleep in Me, is forthcoming in 2010 from the University of Nebraska Press. He teaches in the low-residency MFA program at Queens University of Charlotte
Interview with Jon Baskin--May 15, 2015
No full textJon Baskin is co-founder and editor of The Point magazine in Chicago. He is also a graduate student at the University of Chicago's Committee on Social Thought and the author of many essays and works of criticism for venues such as The Los Angeles Review of Books, The Nation, n+1, The New York Observer, BookForum, Salon, and The Point. Earlier in his career he was a fact checker for various magazines, including Popular Science, Inc Magazine, The Atlantic Monthly, and n+1. The interview was conducted at the office of The Point in Chicago on May 15, 2015.1_izzia9z
Jon Sands, 41st Annual ODU Literary Festival
No full textJon Sands is the author of The New Clean (2011), as well as the co-host of The Poetry Gods podcast. His work has been published widely, and anthologized in The Best American Poetry. He’s a youth mentor with Urban Word-NYC, and teaches creative writing for adults at Bailey House in East Harlem (an HIV/AIDS service center). He’s a recent MFA graduate in fiction from Brooklyn College, where his work won the Himan Brown Award for short stories, and he has represented New York City multiple times at the National Poetry Slam. He lives in Brookly
Essay piece by Jon Hawkins on an altercation that broke out in Portland\u27s Old
No full textEssay piece by Jon Hawkins on an altercation that broke out in Portland\u27s Old Port on Dec. 31 that was characterized by police as a riot. The author, who was the disc jockey at an Old Port pub that night and witnessed the incident, claims the 12 people arrested were reacting to excessive force being used by the police department
Relatively Conscious: The Enduring Rage of Baldwin and the Education of a White Southern Baptist Queer
No full textDelivered in Paris at the 2016 International James Baldwin Conference just two weeks before the killing of 49 individuals at a LGBT nightclub in Orlando, Florida on 26 June 2016, “Relatively Conscious” explores, through the eyes of an LGBT American and the words of James Baldwin, how separate and unequal life remains for so many within the United States. Written in the tradition of memoir, it recounts how, just as Paris saved Baldwin from himself, the writer’s life was transformedupon the discovery of Baldwin
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