1,720,965 research outputs found
Studio di distribuzione del flurazepam e metaboliti in un caso di interesse medico-legale.
No full textContributo sperimentale all'analisi dell'erbicida paraquat in campioni biologici mediante cromatografia liquida ad alta pressione.
No full textSul rilievo di composti 3,4-metilendiossiamfetaminici nell'urina mediante HPLC con rilevazione spettrofotometrica e fluorimetrica.
No full textStudio della correlazione tra livelli ematici e quadro clinico nelle intossicazioni da benzodiazepine osservate presso il servizio di diagnosi chimico-tossicologica di veleno di Pavia.
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Clinical outcome and olanzapine plasma levels in acute schizophrenia
No full textPURPOSE: This open label study was performed to evaluate the relationship between the plasma concentration of olanzapine and the response in acute schizophrenic inpatients.
MATERIAL AND METHODS: A total of 54 inpatients, 38 males and 16 females, age ranging from 18 to 75 years, affected by Schizophrenia (DSM IV criteria) during an exacerbation phase were included in the study. Olanzapine (OLZ) was started at a dose of 5-20 mg/day and was increased to a mean dose of 15.27 mg +/-5.53 S.D. Patients were evaluated at baseline, and after 2 weeks, by using BPRS, PANNS, HRS-D, EPSE, and ACS.
RESULTS: BPRS and total PANSS showed a statistically significant improvement at the end of the study. Olanzapine plasma levels (PL) ranged from 5 to 120 ng/ml (mean 33.15 ng/ml +/- 28.28 S.D.) and showed a positive correlation with OLZ dosage. A significant curvilinear correlation between OLZ PL and clinical improvement (BPRS, PANSS and HRS-D percent of amelioration) was observed.
CONCLUSION: Olanzapine plasma level determination seems to be a useful tool in optimizing acute treatment particularly for more problematic cases
Rilievi clinici e chimico-tossicologici in un caso di intossicazione da colchicina. (In collaborazione con M. L. Baldi, A. Polettini, G. Viglietti, A. Viglietti, E. Migliaccio, P. Bignone e G. Santacroce). Arch. Med. Leg. Ass. 15: 147-154 (1993)
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