1,720,994 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Lack of TNFRI signaling enhances annexin A1 biological activity in intestinal inflammation
Get PDFWe evaluated whether the lack of TNF-α signaling increases mucosal levels of annexin A1 (AnxA1); the hypothesis stems from previous findings showing that TNF-α neutralization in Crohn´s disease patients up-regulates systemic AnxA1 expression. Biopsies from healthy volunteers and patients under anti-TNF-α therapy with remittent ulcerative colitis (UC) showed higher AnxA1 expression than those with active disease. We also evaluated dextran sulfate sodium (DSS)-acute colitis in TNF-α receptor 1 KO (TNFR1-/-) strain with impaired TNF-α signaling and C57BL/6 (WT) mice. Although both strains developed colitis, TNFR1-/- mice showed early clinical recovery, lower myeloperoxidase (MPO) activity and milder histopathological alterations. Colonic epithelium from control and DSS-treated TNFR1-/- mice showed intense AnxA1 expression and AnxA1+ CD4+ and CD8+ T cells were more frequent in TNFR1-/- animals, suggesting an extra supply of AnxA1. The pan antagonist of AnxA1 receptors exacerbated the colitis outcome in TNFR1-/- mice, supporting the pivotal role of AnxA1 in the early recovery. Our findings demonstrate that the TNF-α signaling reduction favors the expression and biological activity of AnxA1 in inflamed intestinal mucosa.Fil: Sena, Angela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; ArgentinaFil: Pedrotti, Luciano Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; ArgentinaFil: Barrios, Bibiana Elisabet. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; ArgentinaFil: Cejas, Hugo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; ArgentinaFil: Balderramo, Domingo. Hospital Privado Centro Medico de Córdoba; ArgentinaFil: Diller, Ana. Hospital Privado Centro Medico de Córdoba; ArgentinaFil: Correa, Silvia Graciela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentin
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Unexpected high seroprevalence of hepatitis E virus in patients with alcohol-related cirrhosis
Get PDF9 p.Fil: Fantilli, Anabella Clara. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Instituto de Virología “Dr. J. M. Vanella"; Argentina.Fil: Fantilli, Anabella Clara. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.Fil: Trinks, Julieta. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Traslacional e Ingeniería Biomédica; Argentina.Fil: Trinks, Julieta. Hospital Italiano de Buenos Aires; Argentina.Fil: Marciano, Sebastián. Hospital Italiano de Buenos Aires. Sección de Hepatología; Argentina.Fil: Marciano, Sebastián. Hospital Italiano de Buenos Aires. Departamento de Investigación; Argentina.Fil: Zárate, Raúl Fabián. Hospital Córdoba; Argentina.Fil: Balderramo, Domingo C. Hospital Privado Universitario de Córdoba. Departamento de Gastroenterología; Argentina.Fil: Balderramo, Domingo C. Instituto Universitario de Ciencias Biomédicas de Córdoba; Argentina.Martínez Wassaf, Maribel G. LACE Laboratorios; Argentina.Fil: Haddad, Leila. Hospital Italiano de Buenos Aires. Sección de Hepatología; Argentina.Fil: Gadano, Adrián. Hospital Italiano de Buenos Aires. Sección de Hepatología; Argentina.Fil: Gadano, Adrián. Hospital Italiano de Buenos Aires. Departamento de Investigación; Argentina.Fil: Debes, José D. University of Minnesota; Estados Unidos.Fil: Pisano, María Belén. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Instituto de Virología “Dr. J. M. Vanella"; Argentina.Fil: Pisano, María Belén. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.Fil: Ré, Viviana Elizabeth. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Instituto de Virología “Dr. J. M. Vanella"; Argentina.Fil: Ré, Viviana Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.Introduction: Little is known about hepatitis E virus (HEV) infection in patients with cirrhosis. The aim of the present study was to describe the frequency of HEV infection and associated risk factors in patients with cirrhosis from Argentina. Materials and methods: We evaluated HEV seroprevalence (IgG anti-HEV) and acute infections (IgM and RNA) in patients with cirrhosis (n = 140) vs. healthy controls (n = 300). Additionally, we compared the same outcomes in individuals with alcohol-related cirrhosis (n = 43) vs. patients with alcohol use disorder (without cirrhosis, n = 72). Results: The overall HEV seroprevalence in the cohort of subjects with cirrhosis was 25% (35/140), compared to 4% in the healthy control group [12/300; OR = 8; (95% CI = 4-15.99); p<0.05]. HEV seropositivity was significantly higher in alcohol-related cirrhosis compared to other causes of cirrhosis [39.5% vs. 12.4%; OR = 4.71; (95% CI = 1.9-11.6); p<0.05] and to healthy controls [OR = 15.7; (95% CI = 6.8-36.4); p = 0.0001]. The HEV seroprevalence in alcoholic-related cirrhosis vs. with alcohol use disorder was 39.5% vs. 12.5% [OR = 4.58; (95% CI = 1.81-11.58); p<0.001]. Conclusion: We found a high seroprevalence of HEV in patients with cirrhosis and in individuals with alcohol use disorder. The simultaneous presence of both factors (cirrhosis + alcohol) showed more association to HEV infection. Larger studies with prospective follow up are needed to further clarify this interaction.publishedVersionFil: Fantilli, Anabella Clara. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Instituto de Virología “Dr. J. M. Vanella"; Argentina.Fil: Fantilli, Anabella Clara. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.Fil: Trinks, Julieta. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Traslacional e Ingeniería Biomédica; Argentina.Fil: Trinks, Julieta. Hospital Italiano de Buenos Aires; Argentina.Fil: Marciano, Sebastián. Hospital Italiano de Buenos Aires. Sección de Hepatología; Argentina.Fil: Marciano, Sebastián. Hospital Italiano de Buenos Aires. Departamento de Investigación; Argentina.Fil: Zárate, Raúl Fabián. Hospital Córdoba; Argentina.Fil: Balderramo, Domingo C. Hospital Privado Universitario de Córdoba. Departamento de Gastroenterología; Argentina.Fil: Balderramo, Domingo C. Instituto Universitario de Ciencias Biomédicas de Córdoba; Argentina.Martínez Wassaf, Maribel G. LACE Laboratorios; Argentina.Fil: Haddad, Leila. Hospital Italiano de Buenos Aires. Sección de Hepatología; Argentina.Fil: Gadano, Adrián. Hospital Italiano de Buenos Aires. Sección de Hepatología; Argentina.Fil: Gadano, Adrián. Hospital Italiano de Buenos Aires. Departamento de Investigación; Argentina.Fil: Debes, José D. University of Minnesota; Estados Unidos.Fil: Pisano, María Belén. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Instituto de Virología “Dr. J. M. Vanella"; Argentina.Fil: Pisano, María Belén. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.Fil: Ré, Viviana Elizabeth. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Instituto de Virología “Dr. J. M. Vanella"; Argentina.Fil: Ré, Viviana Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.Enfermedades Infecciosa
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Influence of dietary triptophan content on the activity of inflamatory bowel disease
Get PDFFil: Tantucci, Leonela Ana. Fundación para el progreso de la Medicina. Servicio de Inmunología; Argentina.Fil: Cabrera, Dafne Soledad. Hospital Privado de Córdoba. Servicio de Gastroenterología; Argentina.Fil: Fernández, Marina Laura. Instituto Universitario de Ciencias Biomédicas de Córdoba. Centro de Investigaciones en Medicina Traslacional Severo Amuchástegui; Argentina.Fil: Cabanillas, Marina. Fundación para el progreso de la Medicina. Servicio de Inmunología; Argentina.Fil: Fochesato, Adriana. Metabolómica Laboratorio Fundación J. Robert Cade; Argentina.Fil: Delgado, Andrea. Metabolómica Laboratorio Fundación J. Robert Cade; ArgentinaFil: Correa, Silvia Graciela. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Centro de Investigaciones en Bioquímica Clínica e Inmunología; ArgentinaFil: Balderramo, Domingo. Hospital Privado Universitario de Córdoba; Argentina.Fil: Romagnoli, Pablo Alberto. Instituto Universitario de Ciencias Biomédicas de Córdoba. Centro de Investigaciones en Medicina Traslacional Severo Amuchástegui; Argentina.Dietary tryptophan is catabolized by the intestinal microbiota into metabolites such as indoles and their derivatives. Our hypothesis proposes that a reduced availability of tryptophan metabolites at the interface of the intestinal mucosa causes a dysregulation of the epithelial barrier that results in Inflammatory Bowel Disease (IBD). To test this hypothesis, we evaluated the content of dietary tryptophan,the circulating tryptophan in plasma and the presence of urinary tryptophan metabolites in 11 control volunteers, 15 patients with Ulcerative Colitis (UC) and 10 patients with Crohn?s Disease (CD). Daily tryptophan intake was calculated based on a food survey by a nutrition health professional, plasma tryptophan levels were measured using high performance liquid chromatography (HPLC) and tryptophan metabolites were determined in urine using mass detector coupled gas chromatography (GC-MS). IBD activity in patientswas clinically estimated using the Mayo index (UC) or the Harvey-Bradshaw index (CD). Dietary and plasmatic tryptophan levelswere comparable in all the study groups. The amount of tryptophanconsumed was directly correlated with the excretion values detectedfor the tryptophan metabolite 1H-indole-2,3-dione (r = 0.7631, p= 0.0168). In addition, non-tryptophan derived metabolites such ascitric acid or 2-hydroxybutyric acid were able to discriminate patientswith IBD from the control group. Although the amount of tryptophanconsumed was not related to the activity of IBD in patients with UC,we found that the amount of tryptophan consumed was inverselycorrelated with the stage of IBD in patients with CD (r = -0.6971, p= 0.0251). Our findings suggest that increasing the amount of tryptophanin the diet may decrease IBD activity in patients with CDand that metabolomic profile of patients with IBD can provide a newprecision medicine tool to improve the management and the qualityof life of patients with IBD.Fil: Tantucci, Leonela Ana. Fundación para el progreso de la Medicina. Servicio de Inmunología; Argentina.Fil: Cabrera, Dafne Soledad. Hospital Privado de Córdoba. Servicio de Gastroenterología; Argentina.Fil: Fernández, Marina Laura. Instituto Universitario de Ciencias Biomédicas de Córdoba. Centro de Investigaciones en Medicina Traslacional Severo Amuchástegui; Argentina.Fil: Cabanillas, Marina. Fundación para el progreso de la Medicina. Servicio de Inmunología; Argentina.Fil: Fochesato, Adriana. Metabolómica Laboratorio Fundación J. Robert Cade; Argentina.Fil: Delgado, Andrea. Metabolómica Laboratorio Fundación J. Robert Cade; ArgentinaFil: Correa, Silvia Graciela. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Centro de Investigaciones en Bioquímica Clínica e Inmunología; ArgentinaFil: Balderramo, Domingo. Hospital Privado Universitario de Córdoba; Argentina.Fil: Romagnoli, Pablo Alberto. Instituto Universitario de Ciencias Biomédicas de Córdoba. Centro de Investigaciones en Medicina Traslacional Severo Amuchástegui; Argentina.Otras Ciencias de la Salu
- …
