694 research outputs found
The Effects of Huanglongbing on Florida Oranges
No full textThis tri-fold brochure offers commercial citrus growers and other stakeholders’ succinct details about the effects of HLB, and presents important facts of HLB’s history in Florida, illustrated descriptions, and details regarding HLB’s effects on fruit yield, appearance, and quality. Includes author contact information. Written by Michelle Danyluk, Timothy M. Spann, Russell Rouseff, Renée M. Goodrich-Schneider, and Charlie Sims and published by the UF Department of Food Science and Human Nutrition, January 2011. Digital edition issued March 2011.
FSHN11-08/FS169: The Effects of Huanglongbing on Florida Oranges (ufl.edu
The Effects of Huanglongbing on Florida Oranges
No full textThis tri-fold brochure offers commercial citrus growers and other stakeholders’ succinct details about the effects of HLB, and presents important facts of HLB’s history in Florida, illustrated descriptions, and details regarding HLB’s effects on fruit yield, appearance, and quality. Includes author contact information. Written by Michelle Danyluk, Timothy M. Spann, Russell Rouseff, Renée M. Goodrich-Schneider, and Charlie Sims and published by the UF Department of Food Science and Human Nutrition, January 2011. Digital edition issued March 2011.
FSHN11-08/FS169: The Effects of Huanglongbing on Florida Oranges (ufl.edu
The Effects of Huanglongbing on Florida Oranges
No full textThis tri-fold brochure offers commercial citrus growers and other stakeholders’ succinct details about the effects of HLB, and presents important facts of HLB’s history in Florida, illustrated descriptions, and details regarding HLB’s effects on fruit yield, appearance, and quality. Includes author contact information. Written by Michelle Danyluk, Timothy M. Spann, Russell Rouseff, Renée M. Goodrich-Schneider, and Charlie Sims and published by the UF Department of Food Science and Human Nutrition, January 2011. Digital edition issued March 2011.
FSHN11-08/FS169: The Effects of Huanglongbing on Florida Oranges (ufl.edu
Diana's shrines turned into ready money, by priestly magic; or, Virtue given up. Being remarks on the Northern Priest's pamphlet, entitled, A-----a known to the A------ts. In a letter to the author. In which is contained an impartial appendix, setting forth the right of the British Parliament, as well as the real advantages that would arise to the honest merchant, by the prevention of the iniquitous practice of smuggling. : [One line in Latin]
No full text23, [1] p. ; 20 cm. (8vo)In reply to Samuel Mather's anonymously published "An attempt to shew, that America must be known to the ancients."Attributed to Timothy Prout by Evans.Printed in New York by H.G. [i.e., Hugh Gaine?] for Ezekiel Russell of Boston. Opposition from the Boston clergy evidently made printing in Boston inadviseable. Cf. p. [3]
Invention and implementation of technologies for continuous flow synthesis
No full textThesis: Ph. D., Massachusetts Institute of Technology, Department of Chemistry, May, 2019Cataloged from the PDF of thesis.Includes bibliographical references.In this thesis, I have optimized a synthesis of rufinamide an important epilepsy medication. This convergent synthesis generates two reactive intermediates in situ (aryl azide and propiolamide) and then combines them in a regioselective click reaction utilizing copper tubing as the catalyst. Next, I have optimized a synthesis of nicardipine which is prescribed to treat high blood pressure. The nature of the project required that the final product be relatively pure (>90 %) so that the final product could be crystallized from the reaction mixture. Nicardipine was synthesized in three steps, but in two flow reactors where one of the reactors induced two steps. The reaction mixture was then purified using two in-line aqueous extrations. First, the reaction stream was washed with HCl to produce the salt of nicardipine and wash away polar compounds. Then, the product is extracted into the aqueous layer by using a 1:1 water DMSO mixture.Finally, the synthesis's scale was increased and run in the system that was created in collaboration with the Jensen lab and Myerson lab. Next, a fully continuous synthesis of linezolid was optimized and run. The synthesis targeted the challenging intermediate amide epoxide that rapidly cyclizes into unwanted oxazolines. We were able to circumvent this side reactivity by masking the nucleophilic amide N-H by quenching the resulting nitrillium after Ritter type reaction with 2-propanol to produce the imidate. After accessing the masked amide epoxide, linezolid was produced by nucleophilic addition to the epoxide with the aniline made from a nucleophilic aromatic substitution (SNAr) reduction sequence. Finally, late stage oxazolidinone formation produces linezolid in a 73% yield in 27 minutes longest linear sequence. Next, I contributed to a system that automatically optimized and analyzed organic reactions in continuous flow.This system in collaboration with the Jensen lab fully integrated software, hardware that controlled the continuous platform, and in-line analytics. This system, after the chemist had provided the desired chemical space, could optimize a reaction without any manual intervention. Finally, I developed a monolithic cellular solid made of functionalized silica for catalyst support. This system could solve some of the problems associated with packed bed reactors including catalyst deactivation due to channeling or clogging of the reactor. This type of catalyst support could be applicable to a large number of catalysts by attaching the catalyst to silane side chains with appended functionality. Portions of this thesis have been published in the following articles co-written by the author and have been reprinted and/or adapted with permission from their respective publishers.Zhang, P.; Russell, M.G.; Jamison, T.F. "Continuous Flow Total Synthesis of Rufinamide" Org. Proc. Res. Dev.2014, 15671570. © 2014 American Chemical Society. MGR ran the optimization of the synthesis as well as isolation and characterization of the final product. PZ wrote the manuscript and validated the results under TFJ's guidance. Zhang, P.; Weeranoppanant, N.; Thomas, D. A.; Tahara, K.; Stelzer, T.; Russell, M. G.; OMahony, M.; Myerson, A. S.; Lin, H.; Kelly, L. P.; Jensen, K. F.; Jamison, T. F.; Dai, C.; Cui, Y.; Briggs, N.; Beingessner, R. L.; Adamo, A. Advaced Continuous Flow Platform for On-Demand Pharmaceutical Manufacturing, Chem. Eur. J. 2018, 24, 2776-2784. DOI: 10.1002/chem.201706004. © 2018 John Wiley & Sons, Inc. MGR optimized the synthesis of nicardipine as well as ran the synthesis in the synthesis frame. PZ, HL, LPK, CD, RLB all woked to develop chemistry for the syntheses of the different drug targets. NW, DAT, and AA worked to develop the up-steam synthesis unit as well as necessary undeveloped components.KT, TS, MM, YC, and NB woked to deleop the continuous recrystalization unit and purified the drug targets. TFJ, KFJ, and ASM provided instrumental guidance to the teams. Russell, M. G.; Jamison, T. F. "Seven-Step Continuous Flow Synthesis of Linezolid Without Intermediate Purification," Angew. Chem Int. Ed. 2019, 58, 7678-7681. DOI: 10.1002/anie.201901814. © 2019 John Wiley & Sons, Inc. All synthetic work was carried out by MGR under TFJ's guidance. B6dard, A.-C.; Adamo, A.; Aroh, K. C.; Russell, M. G.; Bedermann, A. A.; Torosian, J.; Yue, B.; Jensen, K. F.; Jamison, T. F. Reconfigurable System for Automated Optimization of Diverse Chemical Reactions, Science 2018, 361, 1220-1225. © 2018 American Association for the Advancement of Sciences. Reprinted with permission from AAAS. MGR and ACB worked together to run the various optimizations as well as substrate scopes. AAB developed initial conditions for several of the reactions. AA developed the system with JT and BJ's assistance.KCA integrated the system with the software as well as modeled the optimization protocols. KFJ and TFJ provided instrumental guidance to the teams. Leibfarth, F. A.; Russell, M. G.; Langley, D. M.; Seo, H.; Kelly, L. P.; Carney, D. W.; Sello, J. K.; Jamison, T. F. Continuous-Flow Chemistry in Undergraduate Education: Sustainable Conversion of Reclaimed Vegetable Oil into Biodiesel, J. Chem. Ed. 2018, 95, 1371-1375. DOI: 10.1021/acs.jchemed.7b00719. © 2018 American Chemical Society. MGR and DML developed and optimized the chemistry. FAL wrote the manuscript and the laboratory experiment. MGR, HS, and LPK, taught the experiment. DWC provided assistance. JKS and TFJ provided guidance.by Mary Grace Russell.Ph. D.Ph.D. Massachusetts Institute of Technology, Department of Chemistr
Henri Temianka Correspondence; (miscellaneous)
No full textThis collection contains material pertaining to the life, career, and activities of Henri Temianka, violin virtuoso, conductor, music teacher, and author. Materials include correspondence, concert programs and flyers, music scores, photographs, and books.https://digitalcommons.chapman.edu/temianka_correspondence/3223/thumbnail.jp
Interventions in the Delivery of Outpatient Diabetes Care: A systematic review of the literature 2001-2005
No full textCONTEXT: Current practices of outpatient care for type 2 diabetes are not producing adequate patient-oriented outcomes according to the targets established by clinical research trials. OBJECTIVE: To systematically review the best evidence available about the care of diabetes in the outpatient setting. METHODS: The author searched both the PubMed and CINAHL databases for reports of randomized controlled trials and systematic reviews published in English between 2001-2005 that matched the MeSH terms "diabetes" and "outpatient". Articles were then narrowed based on both relevance and quality. Included studies reported patient-oriented outcomes (blood pressure, percent hemoglobin A1c, or blood lipid levels). Interventions were divided into those affecting the setting of care, affecting the process of care, or involving primarily education. RESULTS: Of441 identified articles, 19 met all criteria and were included. Intensive process interventions were effective and generally involved multifaceted case management. Educational interventions were effective in the short term, but benefits did not extend beyond the intervention term for any study. Setting interventions showed no significant benefit. CONCLUSIONS: The literature on this topic is still inconclusive and heterogeneous. The few interventions that showed benefit are highly resource-intensive, and for this reason have significant threats to broad applicability. Successful process interventions require cost-benefit studies to determine their widespread feasibility in varied settings. Neither setting nor education interventions show physiological benefits that justify their cost.Master of Public Healt
Instrumental Vibrato: An Annotated Bibliography of Historical Writings Before 1940
No full textabstract: The use of instrumental vibrato in certain periods of classical music performances has become a highly debated and often fiery topic. The scholars of yesterday had only a few sources with which to gain a better understanding of the definition, mechanics, employment, and prevalent attitudes of those coming before them. This project aims to develop the foundation to a better understanding of instrumental vibrato by compiling primary source material written before 1940 and secondary source material relevant to that period into an annotated bibliography. The source materials in this study were mainly comprised of treatises, tutors, method books, newspaper articles, and dictionaries. The instruments covered in this study included the violin family and relatives (viols, etc...), woodwinds (including recorder), members of the brass family, organ, other keyboard instruments, guitar/banjo/lute, theremin, and prototype/niche instruments (such as player pianos). This project investigated 309 historical documents, finding 258 contained writings about instrumental vibrato. Of those, 157 were presented as bibliographic annotations. The author found no consensus at any time in the history of Western art music between 1550-1940 that vibrato is wholly acceptable or wholly unacceptable.Dissertation/ThesisD.M.A. Music 201
Fossil fuels, global warming and democracy: a report from a scene of the collision
No full textWhat happens to democracy when the fossil fuel industry collides with global warming?
Introduction
Democracy is caught in a collision between two forces: the need to respond to global warming by cutting carbon emissions, and the demands of the fossil fuel industry to increase carbon use and production. This is a slow motion collision that will take decades to conclude, though its ending seems inevitable: coal, and then oil and natural gas, will be replaced by more sustainable energy sources, but only after great damage to the environment.
In this paper I explore the question, What happens to democracy when the fossil fuel industry collides with global warming?
This collision is already making its marks on democratic practices. The fossil fuel industry is using every tool it can to preserve its wealth and power by pressuring governments, political parties, universities, regulators, courts, and voters. It is a process of tough, aggressive, and sophisticated politics that ultimately depends on denying the evidence that global warming poses a danger that needs to be urgently confronted.
Without a theoretical framework to focus this inquiry, it could easily produce little more than a list of anecdotes about politics and influence. The value of good theory is that it reveals the patterns in the evidence, showing how the disparate pieces are connected to one another, and to larger historical, social, and economic factors. In this paper, I drew theory from (among others) Valerie Bunce, Timothy Mitchell, and most importantly Terry Lynn Karl.
I use the work of these scholars to focus on the Canadian province of Alberta. Alberta provides an example of what can happen to democracy in places where fossil fuel production predominates. From time-to-time I link the paper to Australia, which depends even more than Canada on mineral extraction, and which is on the burning edge of global warming.
This paper should be read as a warning to people everywhere who are concerned about fossil fuel dependence, global warming, and democracy. Those who value democracy must ask, Can democracy as we know it survive global warming
Harmony and discord within the English ‘counter-culture’, 1965-1975, with particular reference to the ‘rock operas’ Hair, Godspell, Tommy and Jesus Christ Superstar
No full textPhDThis thesis considers the discrete, historically-specific theatrical and musical sub-genre of ‘Rock Opera’ as a lens through which to examine the cultural, political and social changes that are widely assumed to have characterised ‘The Sixties’ in Britain. The musical and dramatic texts, creation and production of Hair (1967), Tommy (1969), Godspell (1971), Jesus Christ Superstar (1970) and other neglected ‘Rock Operas’ of the period are analysed. Their great popularity with ‘mainstream’ audiences is considered and contrasted with the overwhelmingly negative and often internally contradictory reaction towards them from the English ‘counter-culture’. This examination offers new insights into both the ‘counter-culture’ and the ‘mainstream’ against which it claimed to define and differentiate itself.
The four ‘Rock Operas’, two of which are based upon Christian scriptures, are considered as narratives of spiritual quest. The relationship between the often controversial quests for re-defined forms of faith and the apparently precipitous ‘secularization’ and ‘de-Christianization’ of British society during the 1960s and 1970s is considered.
The thesis therefore analyses the ‘Rock Operas’ as significant, enlightening prisms through which to view many of the profound societal debates – over ‘faith’ and ‘belief’ in the widest senses, sexuality, the Vietnam war, generational conflict, drugs and ‘spiritual enlightenment’, and race – which were, to some considerable extent, elevated onto the national, political agenda by the activities of the broadly-defined ‘counter-culture’. It considers subsequent representations of the ‘counter-culture’ as the root of a contested but enduring popular legacy of ‘The Sixties' as a period of profound cultural change
- …
