186,412 research outputs found
Past medical history and pancreatic cancer risk: Results from a multicenter case-control study
No full textPurposeTo investigate risk factors that may be linked to pancreatic cancer.MethodsWe designed a multicenter population-based case-control (823 cases, 1679 control patients) study with data collection by using a common protocol and questionnaire. Participating centers were located in Australia, Canada, the Netherlands, and Poland.ResultsAfter adjustment for confounding factors, a positive history of pancreatitis was associated with pancreatic cancer (odds ratio [OR], 4.68; 95% confidence interval [95% CI], 2.23-9.84). The risk was especially high in heavy smokers (OR, 15.4; 95% CI, 3.18-74.9). Patients with diabetes had an increased risk of developing pancreatic cancer (OR, 2.16; 95% CI, 1.60-2.91). The risk was highest in the first year after the development of diabetes (OR, 6.68; 95% CI, 3.56-12.6) and decreased over time. A history of allergy was associated with a reduced risk of pancreas cancer (OR, 0.64; 95% CI, 0.50-0.82).ConclusionsPatients with newly diagnosed diabetes and patients with pancreatitis, particularly in heavy smokers, have an increased risk for developing pancreatic cancer. In addition to being risk factors, these conditions could be early manifestations of underlying pancreatic cancer. A history of allergy decreases the risk of pancreatic cancer.Patrick Maisonneuve, Albert B. Lowenfels, H. Bas Bueno-De-Mesquita, Parviz Ghadirian, Peter A. Baghurst, Witold A. Zatonski, Anthony B. Miller, Eric J. Duell, Paolo Boffetta, and Peter Boylehttp://www.elsevier.com/wps/find/journaldescription.cws_home/505746/description#descriptio
Visual evoked potential latencies of three-year-old children prenatally exposed to buprenorphine or methadone compared with non-opioid exposed children: the results of a longitudinal study
No full textAbstract not availableJustine N. Whitham, Nicola J. Spurrier, Peter A. Baghurst, Paul Weston, Michael G. Sawye
Socioeconomic position, maternal IQ, home environment, and cognitive development
No full textCopyright © 2007 Mosby, Inc. All rights reserved.Objective To assess whether socioeconomic position, maternal intelligence (IQ), and the home environment are inter-related to cognitive development in childhood. Study design Prospective cohort study (n = 723) with cognitive tests at ages 2, 4, 7, and 11 to 13 years. Results There were statistically significant positive associations of father’s occupational prestige, Home Observation for Measurement of Environment (HOME) score, and maternal IQ with cognitive performance in childhood. After adjustment for confounding factors, there was an increase in cognitive development by 0.8 to 2.0, 2.9 to 4.8, and 4.2 to 9.0 points for a 10-unit increment in father’s occupational prestige, maternal IQ, and HOME score, respectively. Conclusions These results demonstrate that socioeconomic position, maternal IQ, and the home environment are independently and positively predictive of children’s cognitive development. These findings provide additional rationale for implementing social policies that reduce socioeconomic inequalities.Shilu Tong, Peter Baghurst, Graham Vimpani and Anthony McMichaelhttp://www.elsevier.com/wps/find/journaldescription.cws_home/623311/description#descriptio
Paediatric capsule endoscopy: a single-centre experience
No full textR Abu-Assi, D Moore, P Baghurst, R Butler, P Hammond, R Couper, G Davidso
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
The difference between hazard and risk in the relation between bone density and fracture
No full textThe original publication can be found at www.springerlink.comThe relation between fracture risk and bone density is frequently defined in terms of a relative hazard derived from the Cox proportional hazards model. The relative hazard is a multiplicative factor representing the rise in hazard for each standard deviation fall in bone mineral density, which has a typical value of about 1.5. It is not generally appreciated that this hazard may only be equated with absolute risk when risk is very low; at higher risk and over long periods, it is inappropriate to apply a multiplicative factor to absolute risk because risk has a range of 0-1 and cannot exceed unity. Here, we show how “hazard” can be converted to risk and how misleading the current practice of equating relative hazards with relative risks can be.B. E. Christopher Nordin, Peter A. Baghurst and Andrew Metcalf
Childhood lead exposure, childhood trauma, substance use and subclinical psychotic experiences - a longitudinal cohort study
No full textAvailable online 2 March 2016Abstract not availableCherrie Galletly, Levina Clark, Alexander McFarlane, Amelia Searle, Michael Sawyer, Malcolm Sim, Peter Baghurst, Miranda van Hoof
Prevalence of gastroenteritis among 4-year-old children in South Australia
No full textThe aim of this study was to determine the prevalence of gastroenteritis among children aged 4 years in South Australia. A cross-sectional survey of 9543 South Australian children aged 4 years was undertaken. Parents completed a questionnaire on behalf of their child who had attended a pre-school health check in 1998. The questionnaire covered gastrointestinal and respiratory symptoms experienced by the child in the previous 2 weeks and other risk factors for gastroenteritis. The 2-week prevalence of gastroenteritis among 4-year-old children was 14·2%. The major risk factors for gastroenteritis were presence of persons who had gastroenteritis inside the home, contact with persons who had gastroenteritis outside the home, antibiotic use and sore throat. Medical attention was sought for 20% of children who had gastroenteritis. Gastroenteritis is a significant cause of morbidity among young children and presents a considerable burden on the community. A substantial proportion of these occurrences of highly credible gastrointestinal symptoms may be manifestations of respiratory infections.J. S. Heyworth, P. Baghurst and K. A. McCau
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Tracing the long-term legacy of childhood lead exposure: a review of three decades of the Port Pirie Cohort study
No full textAbstract not availableAmelia K. Searle, Peter A. Baghurst, Miranda van Hooff, Michael G. Sawyer, Malcolm R. Sim, Cherrie Galletly, Levina S. Clark, Alexander C. McFarlan
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