169,768 research outputs found
Transcranial Magnetic Stimulation: From Basic Mechanisms to Clinical Application for Addiction Medicine
No full textrs-fMRI network-based TMS targeting
No full textThe present data are collected from 8 Alzheimer's disease patients to prove the feasibility of a tailored network-based transcranial magnetic stimulation (TMS) targeting approach. Based on resting state functional imaging, the procedure allows to extract individual optimal targets of two networks affected by Alzheimer's disease: the default mode (DMN) and the fronto-parietal network (FPN).
The dataset includes:
- The raw independent components maps (melodic_IC.nii.gz) in native space extracted from individual rs-fMRI with Melodic independent component analysis (Beckman and Smith 2004)
- A table with the demographic and clinical characteristics of the sample (n=8) together with the individual coordinates of the target in native space
Epidemiologia molecolare di Klebsiella pneumoniae produttore di beta-lattamasi ad ampio spettro (ESBL) circolante in una Terapia Intensiva Neonatale
No full textThe molecular epidemiology of extended-spectrum beta-lactamase (ESBL)-producing Klebsiella pneumoniae was investigated in the neonatal intensive care unit (NICU) of a university hospital in Italy from September 2002 to December 2004, when 233 colonizations and 19 infections by K. pneumoniae occurred. Molecular typing by pulsed- field gel electrophoresis (PFGE) and dendrogram analysis of ESBL-producing K. pneumoniae isolates identified two distinct PFGE patterns B and C, that were sequentially isolated and that differed from one epidemic clone of PFGE type A isolated during 1996 in the same ward. Antimicrobial susceptibility patterns of ESBL-producing K. pneumoniae epidemic clones of PFGE type B and C showed an identical antibiotype, that differed from clone of PFGE type A for gentamicin resistance. DNA sequencing of amplified blaTEM and blaSHV genes resulted in the detection of a novel blaTEM ESBL gene, blaTEM-136, along with blaSHV-1 gene, in chromosomal and plasmid DNA from K. pneumoniae of PFGE type A, respectively, and blaTEM-1 and blaSHV-12 genes in chromosomal and plasmid DNA from K. pneumoniae epidemic clone of PFGE type B and C, respectively. Conjugation experiments demonstrated that resistance to third generation cephems, along with blaSHV-12 gene, was transferred from K. pneumoniae epidemic strains of PFGE type B and C to a susceptible E. coli host at a frequency of 4x 10-6 and 1 x 10-6 CFU/recipient cells, respectively. Our data suggest that the selection of ESBL producing clones and the transfer of blaSHV-12 ESBL gene between different clones were responsible for the spread of K. pneumoniae in the NICU
Pseudoneglect is maintained in aging but not in mild Alzheimer's disease: new insights from an enumeration task
No full text
Test di efficacia dei detergenti-biocidi Bat1 e Bat2 di origine naturale su patogeni nosocomiali multiresistenti.
No full textNeural dynamics of multiple object processing in Mild Cognitive Impairment and Alzheimer’s Disease: future early diagnostic biomarkers?
No full textEnhancing cognitive training effects in Alzheimer's disease: rTMS as an add-on treatment
No full textThe treatment of Alzheimer's disease (AD) in the field of non-pharmacological interventions is a challenging issue, given the limited benefits of the available drugs. Cognitive training (CT) represents a commonly recommended strategy in AD. Recently, repetitive transcranial magnetic stimulation (rTMS) has gained increasing attention as a promising therapeutic tool for the treatment of AD, given its ability of enhancing neuroplasticity. In the present randomized, double-blind, sham-controlled study, we aimed at investigating the add-on effect of a high frequency rTMS protocol applied over the left dorsolateral prefrontal cortex (DLPFC) combined with a face-name associative memory CT in the continuum of AD pathology. Fifty patients from a very early to a moderate phase of dementia were randomly assigned to one of two groups: CT plus real rTMS or CT plus placebo rTMS. The results showed that the improvement in the trained associative memory induced with rTMS was superior to that obtained with CT alone. Interestingly, the extent of the additional improvement was affected by disease severity and levels of education, with less impaired and more educated patients showing a greater benefit. When testing for generalization to non-trained cognitive functions, results indicated that patients in CT-real group showed also a greater improvement in visuospatial reasoning than those in the CT-sham group. Interestingly, this improvement persisted over 12 weeks after treatment beginning. The present study provides important hints on the promising therapeutic use of rTMS in AD
VALUTAZIONE DI STABILITA’ DI UNA PALMA PHOENIX DACTYLIFERA (HYBRIDO) METODO VPA - UN CASO PRATICO REALIZZATO IN PIAZZA G. MATTEOTTI (COMUNE DI CARRARA)
No full text- …
