2,095 research outputs found
Barycentered NICER event list from ObsID 1200120106, used in Stingray tutorial
No full text<p>This is a NASA NICER observation of the accreting black hole MAXI 1820+070 during its 2018 outburst</p>
<p>The raw X-ray event data in FITS format were obtained from the NICER archive at HEASARC:</p>
<p>https://heasarc.gsfc.nasa.gov/cgi-bin/W3Browse/w3hdprods.pl?files=Preview&Coordinates=Equatorial&Equinox=2000&CheckSize=1&showgifs=1&Target=heasarc%5Fnicermastr%7C%7C%7C%5F%5Frow%3D30877%7C%7C&popupFrom=&querytime=1708425079</p>
<p>Processing: <br>We ran the barycorr FTOOL, using the JPL DE 430 ephemeris (all details of processing can be found in the header of the FITS file). </p>
<p>We distribute it to be used as practice data for Spectral Timing tutorials. Scientific use might require better processing, involving a re-run of the Level-2 data pipeline.</p>
The high energy X-ray probe (HEX-P): studying extreme accretion with ultraluminous X-ray sources
No full textIntroduction: ultraluminous X-ray sources (ULXs) represent an extreme class of accreting compact objects: from the identification of some of the accretors as neutron stars to the detection of powerful winds travelling at 0.1–0.2 c, the increasing evidence points towards ULXs harbouring stellar-mass compact objects undergoing highly super-Eddington accretion. Measuring their intrinsic properties, such as the accretion rate onto the compact object, the outflow rate, the masses of accretor/companion-hence their progenitors, lifetimes, and future evolution-is challenging due to ULXs being mostly extragalactic and in crowded fields. Yet ULXs represent our best opportunity to understand super-Eddington accretion physics and the paths through binary evolution to eventual double compact object binaries and gravitational-wave sources.Methods: through a combination of end-to-end and single-source simulations, we investigate the ability of HEX-P to study ULXs in the context of their host galaxies and compare it to XMM-Newton and NuSTAR, the current instruments with the most similar capabilities.Results: HEX-P’s higher sensitivity, which is driven by its narrow point-spread function and low background, allows it to detect pulsations and broad spectral features from ULXs better than XMM-Newton and NuSTAR.Discussion: we describe the value of HEX-P in understanding ULXs and their associated key physics, through a combination of broadband sensitivity, timing resolution, and angular resolution, which make the mission ideal for pulsation detection and low-background, broadband spectral studies
Complementary feed for the control of pruritus in atopic dermatitis in dogs
No full textPruritus is a common manifestation in dogs with allergic skin diseases and itching can significantly affect the
quality of life of both affected animals and their owners, with even severe repercussions [1]. Pharmacological treatments and complementary feeds that are able to control itching quickly and in the long run are in great demand
and attract the attention of many researchers and companies. The aim of this study was to assess the effectiveness
of a complementary feed containing flavonoids, stilbenes, and cannabinoids (obtained from vegetable/botanical by- products/vegetable/botanical source) in the control of itching in dogs suffering from atopic dermatitis. Such complementary feed has been shown to be able to reduce the gene expression of ccl2, ccl17, il31ra and tslp in an experimental in vitro model of atopic dermatitis [3]. The primary efficacy endpoint was the reduction of CADESI-04
and pruritus visual analogue scale (pVas) scores. The study protocol was successfully submitted to the Animal Welfare Body of the University of Camerino (protocol code 10/2021). Ten dogs affected by atopic dermatitis, diagnosed according to current guidelines [1, 2], received a hypoallergenic food for the duration of the study. Once enrolled, in the first 6 weeks dogs received the administration of oclacitinib (Apoquel®, Zoetis) twice daily for two weeks and then once daily for 4 weeks. Starting from the fifth week, the administration of complementary feed began, according to the following dosage: twice daily for two weeks and then once daily for 8 weeks. Administration
of oclacitinib was discontinued at week 6 in all dogs enrolled in the study, who received the complementary feed up to week 12. In all dogs there was a marked reduction in both CADESI-04 and owner-reported pVas for pruritus in
the first four weeks of oclacitinib administration. In the fifth and sixth week of the study (oclacitinib + complementary feed) the trend of CADESI-04 and pVas was the same, as well as from the seventh week onwards for all dogs enrolled in the study. Although data collected are only preliminary, it is possible to highlight that the
complementary feed effectively control itching in supplemented dogs, which did not show any adverse event. This study further confirm the ability of selected complementary feed to control dermatological disease manifestation in dogs [4].
COMPLEMENTARY FEED FOR THE CONTROL OF PRURITUS IN ATOPIC DERMATITIS IN DOGS
Andrea Marchegiani (1), Alessandro Fruganti (1), Elena Dalle Vedove (2), Benedetta Bachetti (2), Marcella Massimini (2), Cataldo Ribecco (2), Matteo Cerquetella (1), AndreaSpaterna (1)
(1) Università degli Studi di Camerino, Scuola di Bioscienze e Medicina Veterinaria. (2) Research and Development Unit (NIL), C.I.A.M. srl.
Corresponding author: A. Marchegiani ([email protected])
[1] Favrot C et al. A prospective study on the clinical features of chronic canine atopic dermatitis and its diagnosis. Vet Dermatol, 21:23–31, 2010.
[2] Hensel P et al. Canine atopic dermatitis: detailed guidelines for diagnosis and allergen identification. BMC Vet Res, 11(1):196, 2015.
[3] Massimini M et al. Polyphenols and Cannabidiol Modulate Transcriptional Regulation of Th1/Th 2 Inflammatory Genes Related to Canine Atopic Dermatitis. Front Vet Sci, 8:1–14, 2021.
[ 4] M arc hegi ani A et al . Im pac t o f N utri ti o na l Supplementation on Canine Dermatological Disorders. Vet Sci MDPI, 38:1–13, 2020
TUTELA DEL LAVORO E LIBERTA' D'IMPRESA NEI PROCESSI DI ESTERNALIZZAZIONE
No full textL’elaborato analizza le conseguenze lavoristiche della successione fra imprenditori, muovendo da una ricognizione delle varie tipologie di esternalizzazione con le relative esigenze e principali criticità.
L’indagine si concentra in primo luogo sul trasferimento d’azienda, esaminando la normativa e la giurisprudenza europee per passare poi alla disciplina di diritto interno, alle procedure sindacali e a uno specifico focus sul trasferimento delle aziende in crisi.
Successivamente l’autore si sofferma sull’appalto, prendendone in particolare considerazione gli indici di genuinità, i criteri di distinzione dalla somministrazione illecita di manodopera e la tutela delle maestranze in caso di avvicendamento fra imprese.
Da ultimo, la ricerca approfondisce le c.d. “clausole sociali”, sia di prima che di seconda generazione, valutandone la compatibilità con il diritto eurounitario e con la costituzione nonché riflettendo sui possibili rimedi in caso di loro violazione.The author analyzes the labour consequences of the succession between entrepreneurs, starting from a recognition of the various types of outsourcing with the related needs and main critical issues.
The survey focuses primarily on the transfer of businesses, examining European legislation and case-law and then moving on to internal legislation, trade union procedures and a specific focus on the transfer of companies in crisis.
The author then dwells on the contract, taking into account in particular the indications of authenticity, the criteria of distinction from the illicit administration of labour and the protection of workers in the event of turnover between companies.
Finally, the research deepens the "social clauses", both first and second generation, assessing their compatibility with European law and with the constitution and reflecting on possible remedies in case of their violation
No Time for Dead Time: Use the Fourier Amplitude Differences to Normalize Dead-time-affected Periodograms
No full textDead time affects many of the instruments used in X-ray astronomy, by producing a strong distortion in power density spectra. This can make it difficult to model the aperiodic variability of the source or look for quasi-periodic oscillations. Whereas in some instruments a simple a priori correction for dead-time-affected power spectra is possible, this is not the case for others such as NuSTAR, where the dead time is non-constant and long (~2.5 ms). Bachetti et al. (2015) suggested the cospectrum obtained from light curves of independent detectors within the same instrument as a possible way out, but this solution has always only been a partial one: the measured rms was still affected by dead time because the width of the power distribution of the cospectrum was modulated by dead time in a frequency-dependent way. In this Letter, we suggest a new, powerful method to normalize dead-time-affected cospectra and power density spectra. Our approach uses the difference of the Fourier amplitudes from two independent detectors to characterize and filter out the effect of dead time. This method is crucially important for the accurate modeling of periodograms derived from instruments affected by dead time on board current missions like NuSTAR and Astrosat, but also future missions such as IXPE
Ultra Low Carbon Vehicles: New Parameters for Automotive Design
No full textAs the influence of vehicle emissions on our environment has become better understood, the UK government has recently placed urgent emphasis on the implementation of low carbon
technologies in the automotive industry through: the UK Low Carbon Industrial Strategy. The overall objective is to offer big incentives to consumers and support for the development of infrastructure and engineering solutions. This scheme however does not consider how the development of functional and experiential user value might drive consumer demand, contributing to the adoption of low carbon vehicles (LCVs) in the mass market.
With the emergence of the North East of England as the UK’s first specialised region for the development of ultra-low carbon vehicles (ULCVs), ONE North East, as a development agency for the region's economic and business development, and Northumbria University Ideas-lab have supported a project to facilitate innovation through the collaboration of technology, research and development (R&D) and business. The High Value Low Carbon (HVLC) project aims to envisage
new user value made possible by the integration of low carbon vehicle platforms with new process and network technologies. The HVLC consortium represents vehicle manufacturers and their suppliers as well as technology based companies and through an ongoing process of design concept generation the project offers a hub for innovation led enterprise.
Whilst new technological developments in areas such as power generation, nano materials, hydrogen fuel cells, printed electronics and networked communications will all impact on future automotive design, the mass adoption of low carbon technologies represents a paradigm shift for the motorist. This paper aims to describe how the mapping of new parameters will lead to new transport scenarios that will create the space for new collaborative research on user experiences supported by innovative technologies and related services
NuSTAR DETECTION OF HARD X-RAY PHASE LAGS FROM THE ACCRETING PULSAR GS 0834−430
No full textAuthors: - Hiromasa Miyasaka, Matteo Bachetti, Fiona A. Harrison, Felix Fürst, Didier Barret, Eric C. Bellm, Steven E. Boggs, Deepto Chakrabarty, Jerome Chenevez, Finn E. Christensen, William W. Craig, Brian W. Grefenstette, Charles J. Hailey, Kristin K. Madsen, Lorenzo Natalucci, Katja Pottschmidt, Daniel Stern, John A. Tomsick, Dominic J. Walton, Jörn Wilms, and William ZhangThe Nuclear Spectroscopic Telescope Array hard X-ray telescope observed the transient Be/X-ray binary GS 0834−430 during its 2012 outburst—the first active state of this system observed in the past 19 yr. We performed timing and spectral analysis and measured the X-ray spectrum between 3–79 keV with high statistical significance. We find the phase-averaged spectrum to be consistent with that observed in many other magnetized, accreting pulsars. We fail to detect cyclotron resonance scattering features that would allow us to constrain the pulsar's magnetic field in either phase-averaged or phase-resolved spectra. Timing analysis shows a clearly detected pulse period of ∼12.29 s in all energy bands. The pulse profiles show a strong, energy-dependent hard phase lag of up to 0.3 cycles in phase, or about 4 s. Such dramatic energy-dependent lags in the pulse profile have never before been reported in high-mass X-ray binary pulsars. Previously reported lags have been significantly smaller in phase and restricted to low energies (E < 10 keV). We investigate the possible mechanisms that might produce this energy-dependent pulse phase shift. We find the most likely explanation for this effect is a complex beam geometry.This work was supported under NASA contract No. NNG08FD60C and made use of data from the NuSTAR mission, a project led by the California Institute of Technology, managed by the Jet Propulsion Laboratory, and funded by the National Aeronautics and Space Administration. We thank the NuSTAR Operations, Software, and Calibration teams for support with the execution and analysis of these observations. This research has made use of the NuSTAR Data Analysis Software (NuSTARDAS) jointly developed by the ASI Science Data Center (ASDC, Italy) and the California Institute of Technology (USA). Matteo Bachetti wishes to acknowledge the support from the Centre National d'Etudes Spatiales (CNES). Lorenzo Natalucci acknowledges financial support through contract ASI/INAF I/037/12/0.https://iopscience.iop.org/article/10.1088/0004-637X/775/1/6
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Matteo Maria Boiardo (1441-1494)
No full textMatteo Maria Boiardo – contemporary of Sir Thomas Malory and forerunner of Shakespeare, Spenser, Milton, Cervantes, Tolkien, and C.S. Lewis – is best known as the author of the Orlando Innamorato [Orlando in Love], a poem in ottava rima organically merging Carolingian epic and Arthurian romance. He was also a lyric and pastoral poet, playwright, and translator of classical texts into the Italian vernacular. Matteo was active in Italy during the years of 1463 throughout 1494, the year of his death
Uno sguardo all'Est. Lavoro e diritti fondamentali in Russia e negli altri Paesi della Comunità di Stati indipendenti
No full textNel contributo l'autore, dopo aver esaminato i diritti fondamentali del lavoro presenti nelle Costituzioni dei Paesi della Comunità di Stati indipendenti, si sofferma sul diritto del lavoro russo. La trattazione, a carattere diacronico, abbraccia i rami principali del diritto del lavoro: il rapporto individuale, le relazioni collettive, il mercato del lavoro. L'autore rileva una sorprendente continuità nelle linee essenziali del diritto del lavoro russo, pur nel susseguirsi di sistemi socioeconomici completamente diversi. Egli conclude che il diritto del lavoro russo appartiene saldamente alla matrice europea della materia.The contribution of the author starts by examining fundamental labour rights recognised by the Constitutions of the Countries of the Community of Independent States. Then the author focuses upon Russian Labour Law, going through the history of the main branches of the discipline: the individual relationship, industrial relations, the labour market. The article finds a surprising continuity in the essential lines of Russian Labour Law, in spite of the completely different socio-economic systems that were experimented in Russia during the twentieth century. The author concludes that Russian Labour Law clearly belongs to the European matrix of the discipline
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