1,721,022 research outputs found
Rhabdomyoma of the vagina.
No full textAnn Pathol. 2012 Feb;32(1):53-7. Epub 2012 Jan 14.
[Rhabdomyoma of the vagina. Case report and short literature review].
Patrelli TS, Franchi L, Gizzo S, Kiener A, Berretta R, Piantelli G, Caruana P, Battista Nardelli G, Bacchi Modena A.
SourceUniversità degli Studi di Parma, Clinica Ginecologica ed Ostetrica, Parma, Italie.
Abstract
The differential diagnosis of vaginal polypoid masses should take rhabdomyoma into consideration even it is an extremely rare tumor. The present report describes a vaginal cystic mass located in the anterior wall of an asymptomatic, 38-year-old, Caucasian, nulliparous woman. Local excision and subsequent pathological examination were performed. The final diagnosis was vaginal rhabdomyoma. The literature is reviewed and differential diagnosis are discussed
Squamotransitional cell carcinoma of the vagina: diagnosis and clinical management: a literature review starting from a rare case report.
No full textPathol Oncol Res. 2011 Mar;17(1):149-53. Epub 2010 May 30.
Squamotransitional cell carcinoma of the vagina: diagnosis and clinical management: a literature review starting from a rare case report.
Patrelli TS, Silini EM, Berretta R, Thai E, Gizzo S, Bacchi Modena A, Nardelli GB.
SourceOb/Gyn Clinic, University of Parma, Parma, Italy. [email protected]
Abstract
Primary squamotransitional cell carcinoma (STCC) is rare squamous cell tumor variant resembling transitional cell carcinoma (TCC) of the urinary tract. STCC occurs rarely in the vagina and its clinical and pathological correlates are poorly known. We report a unique case of a 66-year-old Italian woman with STCC of the vagina. A biopsy of the tumor was performed. The tumor qualified as a STCC. Following biopsy, the patient underwent radical hysterectomy (Piver's III-type) with bilateral salpingo-oophorectomy, upper colpectomy, appendicectomy, peritoneal cytology, and lymphadenectomy. The patient is now healthy without evidence of recurrence at 30 months after surgery. Pathologically, cytoarchitectural characteristics distinguish this histotype (STCC) from conventional squamous cell carcinoma of the genital tract. The cytokeratin staining pattern (CK7 positive and CK20 negative), the p63 expression and the positivity for p16ink4a and high-risk HPV are the main elements of differential diagnosis. We suggest that STCC of the vagina should be treated by radical surgery, possibly followed by adjuvant therapy based on staging results and should receive a long-term follow-up
Pelvic lymphadenectomy in endometrial cancer: our current experience.
No full textEur J Gynaecol Oncol. 2009;30(5):536-8.
Pelvic lymphadenectomy in endometrial cancer: our current experience.
Patrelli TS, Berretta R, Rolla M, Vandi F, Capobianco G, Gramellini D, Bacchi Modena A, Nardelli GB.
SourceDepartment of Gynecology, Obstetrics and Neonatology, University of Parma, Italy. [email protected]
Abstract
OBJECTIVE: Lymph node involvement is the single most important factor in the prognosis of endometrial cancer, because it is predictive of locoregional and distant metastases. The purpose of our study was to determine whether lymphadenectomy is useful in the surgical staging of endometrial cancer and if it may help establish a more accurate prognosis and reduce the need for postoperative therapy in patients without surgical complications.
STUDY DESIGN: We conducted a retrospective study on 55 patients with diagnosis of endometrial cancer.
RESULTS: Surgical staging of patients undergoing pelvic lymphadenectomy (47/55) showed that 59.6% of cases (n = 28) had Stage I cancer (IA in 4, IB in 16, IC in 8), 17.02% (n = 8) Stage II (IIA in 3, IIB in 5), 21.2% (n = 10) Stage III (IIIB in 5, IIIC in 5), and 2.1% (n = 1) Stage IVA. In the remaining eight patients with a very high anesthesiologic risk (ASA 4), surgical staging was incomplete because they underwent only node palpation.
CONCLUSION: In conclusion, as we wait for the sentinel lymph node technique to demonstrate satisfactory results and be standardized also for endometrial cancer, we believe that surgical lymph node dissection plays a crucial role in debulking this type of cancer. When performed by a good surgical oncology team, it does not entail a significantly increased operative risk
Role of D-dimer testing in severe pelvic inflammatory disease: a new usable marker to assess the need for fertility-impairing surgery?
No full textFertil Steril. 2010 Nov;94(6):2372-5. Epub 2010 May 14.
Role of D-dimer testing in severe pelvic inflammatory disease: a new usable marker to assess the need for fertility-impairing surgery?
Franchi L, Patrelli TS, Berretta R, Rolla M, Gizzo S, Gramellini D, Bacchi Modena A, Nardelli GB.
SourceDepartment of Maternal and Child Health, OB/GYN Unit, University of Parma, Parma, Italy.
Abstract
Pelvic inflammatory disease (PID), like many other inflammatory diseases, can be characterized by an inflammation-induced activation of the coagulation cascade, resulting in the production of D-dimers. In this study it is demonstrated how high levels of D-dimers, assayed at the time of hospitalization, are encountered in patients diagnosed with PID and how the levels of this parameter are significantly higher in patients, which due to the severity of the disease, needed surgical treatment. Therefore the d-dimer is shown to be an important parameter to be considered in the therapeutic counseling of severe forms of PI
Preterm delivery and premature rupture of membranes after conization in 80 women. Preliminary data.
No full textMinerva Ginecol. 2008 Aug;60(4):295-8.
Preterm delivery and premature rupture of membranes after conization in 80 women. Preliminary data.
Patrelli TS, Anfuso S, Vandi F, Valitutto S, Migliore M, Salvati MA, De Ioris A, Condemi V, Fadda GM, Bacchi Modena A, Nardelli GB.
SourceDepartment of Obstetrics, Gynecology and Neonatology, University of Parma, Parma, Italy. [email protected]
Abstract
AIM: Cervical intraepithelial neoplasia is most frequently in young women in reproductive age. Cold knife conization, laser ablation, laser conization and large loop excision are conservative methods of treatment to remove the transformation zone and preserve the cervical function. Previous studies have shown conflicting results on the outcomes of pregnancy following these therapies that might increase the risk of preterm delivery. The purpose of this study was to evaluate the outcome of pregnancy after conization and its role as predictive risk factor.
METHODS: A retrospective study was performed. The study group comprised 80 women who had a conization and that had a subsequent singleton pregnancy. Variables considered includes maternal excision date, surgery procedure, previous surgery treatments, time interval between excisional procedure and subsequent pregnancy; duration and week of pregnancy, mode of delivery, histological grading (no cervical intraepithelial neoplasia [CIN], CIN 1, CIN 2-3) and cone excised depth.
RESULTS: In group study 45 women underwent loop electrosurgical excision procedure (LEEP) conization, 32 cold knife conization and 3 laser CO2. The authors found 11 cases of cone tissue depth1 cm. Eight preterm delivery have been reported to data: 5 between 28 and 34 weeks, 2 lower than 28 weeks and 1 between 34 and 37 weeks.
CONCLUSION: In these preliminary data the percentage of preterm birth appears as 10% and in range 6-15% evaluated for women not submitted to excisional procedure
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