1,721,089 research outputs found
MARINO M, POLIZZI M, SARNATARO E, CASCELLA R MARESCA R, CASTALDO L, RICCIO MP, PASCOTTO A, BRAVACCIO C (2010). Association of maternal lifestyle factors in pregnancy and birth weight with attention-deficit/hyperactivity disorder in a population of Italian children.
No full textFocal polymicrogyria, continuous spike-and-wave discharges during slow-wave sleep and Cohen syndrome: a case report.
No full textGut-brain axis: A new revolution to understand the pathogenesis of autism and other severe neurological diseases
No full textThe gut-brain axis (GBA) is a complex communication network interfacing the gut and the brain of a single individual. The central (CNS) and enteric (ENS) nervous systems are, of course, communicating; however, other pathways are involved in GBA, among which are immune activation, intestinal barrier function, and enteroendocrine signaling. All these communication lines are bidirectional and involve neuro-immuno-endocrine mediators. The reason for the development of such a complex network is to maintain gastrointestinal homeostasis keeping in mind its links with cognitive and affective functions. Recently, the role of enteric flora, or microbiota, has been recognized as a part of the gut-brain axis. The gut microbiota can modulate brain function, forming a crucial link in the bidirectional interactions between the intestine and the nervous system
Unusual compulsive motor activity during treatment with clothiapine in a mentally retarded adolescent
Full text linkAtypical antipsychotic agents, specifically those with a high hyposerotonergic activity such as clozapine and clothiapine, have been
associated with de novo obsessive–compulsive symptoms. We report the case of a 16-year-old adolescent male with severe mental
impairment and disruptive behaviour who developed a compulsive head and body turning disorder on clothiapine. Such a symptom had to be
distinguished from epileptic partial seizures; it promptly disappeared with the drug discontinuation
APPLICAZIONE DI UNA SCALA DI VALUTAZIONE DEGLI ATTEGGIAMENTI NEI CONFRONTI DEGLI EPILETTICI
No full textDistribution and age of onset of psychopathological risk in a cohort of children with Down syndrome in developmental age.
No full textBackground: Aim of the study is to intercept specific characteristics and psychiatric comorbidity in Down Syndrome (DS). The study describes the distribution and the age of specific aspects of behavioral phenotype in a sample of subjects with DS.
Methods: Psychopathological risk has been evaluated in a 97 DS patient cohort, aged 1 to 18 years, during regular follow-up neuropsychiatric visit and through administration of Child Behavior Checklist (CBCL); Childhood Autism Rating Scale (CARS-T) was assessed to verify the presence of autistic behaviors.
Results: The results show the presence of specific psychopathological risk factors in 90% of the sample. 7% of sample presents autistic features. The risk of psychopathology is independent of the degree of intellectual disability.
Conclusion: The high frequency of psychopathological risk factors indicates the need for accurate monitoring to intercept specific characteristics, such as in the case of comorbidity for autism. The search for specific psychopathological factors is a little explored aspect to date, as evidenced by the literature. Despite the studies available to date highlight the presence of psychopathological vulnerability in DS, so far there are only few reports that explore this issue systematically.
Keywords: Attention deficit/hyperactive disorder; Autism Spectrum disorder; Down syndrome; Oppositional defiant disorder;psychopathological risk
Continuity of care. Patient support from hospital-to-territory care plan: protected hospital discharges
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