1,721,019 research outputs found
National scientific associations should have a key role in adapting and implementing standard of care guidelines in European countries
No full text: Braggion C, Alatri F, Conese M, Festini F, Gagliardini R, Raia V, Seia M, Taccetti G; Executive Committee of the Italian Cystic Fibrosis Society. Related Articles, Links National scientific associations should have a key role in adapting and implementing standard of care guidelines in European countries. J Cyst Fibros. 2005 Dec;4(4):271-2. Epub 2005 Oct 25. No abstract available
Travel-associated Burkholderia pseudomallei infection (Melioidosis) in a patient with cystic fibrosis: A case report
No full textTravel-associated Burkholderia pseudomallei infection (melioidiosis) in a cystic fibrosis patient: a case report
No full textIn September 1997, a 25-year-old Italian woman with cystic fibrosis (CF) spent 3 weeks in Thailand. In August 1998, her pulmonary function rapidly declined, with productive cough and intermittent fever. Chest x-ray films revealed diffuse, small, patchy opacities in the upper lobes. Burkholderia pseudomallei (BP) was isolated from specimens of the patient's sputum and was identified by means of 16S rDNA sequencing. The diagnosis of melioidosis was serologically confirmed. Continuous therapy with ceftazidime and co-trimoxazole and maintenance with co-trimoxazole, doxycycline, and chloramphenicol resulted in eradication of BP. We present the issue of whether patients with CF represent a population particularly at risk for melioidosis
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Exercise tolerance and effects of training in young patients with cystic fibrosis and mild airway obstruction
No full textWe evaluated the effects of an 8-week aerobic training (1 hr, three times a week) on physical performance of ten patients with cystic fibrosis (CF) (median age, 12.5 yr; range 11.1-15.3 yr), with mild airway obstruction (FEV1 = 77 +/- 22% pred.), and ten healthy age-matched children (CONTR) (median age, 12.7 yr; range 12.2-15.2 yr). Physical performance was tested with maximal incremental (MAX) and submaximal (SMAX) (fixed workload of 1.7 W/kg during 6 min) exercise tests on a cycle ergometer. These and standard spirometric and anthropometric measurements were performed at the beginning and end of a period with usual daily activity and one with the training program. The kinetics of ventilatory parameters at the onset and end of SMAX were displayed by fitting data on oxygen uptake and minute ventilation by monoexponential curves (least-squares method). At the start and the end of the training period, all children were timed for endurance run to voluntary exhaustion and for sprinting through an obstacle course. A pattern of relative hyperventilation during SMAX and of poor performance in endurance and obstacle runs were evident at the start of the training period in patients with CF. The effects of training on MAX and SMAX were small and partial; the improvement in field test performances was significant only for CF and could be attributed to improvement of skill and motivation
Prevalence and correlates of vertebral fractures in adults with cystic fibrosis
No full textINTRODUCTION:
Osteoporosis associated with cystic fibrosis (CF) is becoming increasingly important as the life expectancy of patients continues to increase.
MATERIALS AND METHODS:
We studied 191 adults with CF (18-50 years old; 100 men, 91 women). Total body, lumbar spine, and total proximal femur bone mineral density (BMD) were measured by dual-energy X-ray absorptiometry, and lateral spinal radiographs were taken for assessment of vertebral fractures. A range of anthropometric, clinical and biochemical variables were evaluated as potential correlates.
RESULTS:
BMD T score values at the lumbar spine lower than -2.5 SD were observed in 27.3% and 11.2% of male and female patients, respectively. These proportions fell to 14% and 9.9% for total hip and 10.4% and 12.1% for total body, in men and women, respectively. Vertebral deformities were identified in 26.7% of the patients with a slightly higher prevalence in males (32%) than in females (21%, P = 0.058). Multiple vertebral deformities were observed in 12% and 7.7% of men and women, respectively. BMD values were significantly related to body weight, FEV1, age of puberty and occasionally to cumulative steroid dose in both genders. BMD values were also significantly related with serum albumin, IgG and cholinesterase. Serum estradiol levels were found below the normal range in 23% of the women and 27% of the men, and was significantly related to femur BMD values in both women and men. Significantly lower serum estradiol and free testosterone levels were observed in men with vertebral fractures. Serum osteocalcin was below the normal range in 36% and urinary deoxypyridinoline above the normal range in 51% of the patients.
CONCLUSIONS:
This study indicates that osteoporosis is a common complication of CF, being related to disease progression and apparently due to both excess bone resorption and inadequate bone formation. Estradiol deficiency may have a significant role in the pathogenesis in both genders. Vertebral fracture prevalence is high and greater than expected from prevalent BMD values
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
- …
