1,721,027 research outputs found
Convenient use of carbetocin during 70 elective cae- sarean deliveries [Praticità d'uso della carbetocina durante 70 tagli cesarei elettivi]
No full textObjective. To analyze the efficacy of a potent analogue of oxytocin during elective caesarean delivery. Study design. This clinical-pharmacologic case-control study was conducted prospectively in 70 pregnant women scheduled for c-section, 60 patients with a singleton pregnancy and ten with a twin pregnancy. We compared our standard uterotonic protocol (oxytocin plus ergometrine) versus a single intravenous bolus injection of 100 μg of carbetocin, administered immediately after foetal delivery in controlling perioperative blood loss. Results. The patients (30 with 1-2 previous CS, 10 with twin pregnancy and 30 with other indications for elective CS) were similar about their epidemiologic characteristics. Mean blood loss with carbetocin was 523 mL compared to 483 mL with oxytocin plus ergometrine (n.s.). The economic costs were higher in cases compared to controls (nearly 30 versus 8,5-11,5 euros). Conclusions. Carbetocin is a valid alternative to traditional uterotonic treatment with similar efficacy but easier to handle. In terms of handly and nursing the ratio cost/benefit is undoubtedly in favour of carbetoci
Confined space design by nanoparticle self-assembly
Full text linkNanoparticle (NP) self-assembly has led to the fabrication of an array of functional nanoscale systems, having diverse architectures and functionalities. In this perspective, we discuss the design and application of NP suprastructures (SPs) characterized by nanoconfined compartments in their self-assembled framework, providing an overview about SP synthetic strategies reported to date and the role of their confined nanocavities in applications in several high-end fields. We also set to give our contribution towards the formation of more advanced nanocompartmentalized SPs able to work in dynamic manners, discussing the opportunities of further advances in NP self-assembly and SP research
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Multibranched superfluorinated molecular probes for 19F MRI
No full text19F MRI has been emerging as promising whole-body imaging technique complementary to 1H MRI. In fact, 19F has 100% natural abundance, a gyromagnetic ratio very close to that of the proton and 83% sensitivity of 1H. Moreover, in the human body there are only low amounts of inorganic fluorine in bones and teeth, which are not detectable by 19F MRI due to their low T2. Thus, the only in vivo detectable fluorine comes from exogenous tracers that can be clearly imaged and quantified by 19F MRI. However, the intrinsically low sensitivity of MRI has prompted efforts to develop effective 19F MRI tracers. An ideal 19F MRI tracer should have a high number of equivalent 19F atoms to yield a single sharp resonance signal [1]. In this sense, the first molecules used as 19F MRI tracers were perfluorocarbons (PFC) containing a high number of nonequivalent 19F atoms, such as perfluoro-octyl-bromide (PFOB), perfluorodecaline (PFD) and perfluorotributylamine (PFTBA). Later, PFC bearing many equivalent 19F atoms, such as perfluoro-15-crown ether (PFCE), and blends of perfluoropolyethers (PFPE) containing a huge number of 19F atoms (pseudoequivalent), were also proposed as more sensitive 19F MRI tracers [2, 3] (see Fig. 3.1). Despite PFC being widely used as 19F MRI agents, they were not specifically designed for this function, and thus, it should be possible to produce tailored polyfluorinated molecules for sensitive19F MRI
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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