1,721,029 research outputs found
VHH CONSTRUCTS FOR DIVERTING AN IMMUNE RESPONSE
No full textThe invention relates to a novel VHH construct which can be bound by a complete antibody without the antigen-binding properties of said VHH construct being adversely affected. The invention also relates to an antibody construct comprising such a VHH construct and a kit, as well as to the use of same in immunodiagnostics or in therapy. The invention allows, inter alia, the existing immunity of a patient to be directed towards another antigen
HIGH THROUGHPUT METHOD FOR DETERMINING THE PRESENCE OF PAPILLOMAVIRUS-NEUTRALIZING ANTIBODIES IN A SAMPLE.Application No. 10164765.9 - 2404 Deutsches Krebsforschungszentrum (DKFZ - Heidelberg)
No full textSearch of Somatic Morphogenesis in in vitro Grown Plant Tissues by "mRNA Differential Display
No full textIMMUNOGENIC POLYPEPTIDES COMPRISING A SCAFFOLD POLYPEPTIDE AND A L2 POLYPEPTIDE OR FRAGMENT THEREOF (EP2376525B1)
No full textThe present invention relates to an immunogenic polypeptide comprising a) a scaffold polypeptide, and b) a L2 polypeptide or a fragment of said L2 polypeptide, wherein said scaffold polypeptide constrains the structure of said L2 polypeptide, or of a fragment of said L2 polypeptide. Moreover, the present invention relates to a vaccine comprising said immunogenic polypeptide. The present invention is also concerned with a method for producing an antibody against human papillomavirus. Also encompassed by the present invention is an antibody obtained by carrying out the said method
IMPROVEMENT OF HPV L2 PEPTIDE IMMUNOGENICITY
No full textThe present invention relates to an immunogenic polypeptide comprising a multitude of human papillomavirus (HPV) L2 N-terminal peptides corresponding to amino acids 20 to 50 of the L2 polypeptide of HPV16, wherein said HPV L2 N-terminal peptides are L2 N-terminal peptides from at least two different HPV genotypes. The present invention also relates to said immunogenic polypeptide for use in medicine and for use in vaccination against HPV infection. Moreover, the present invention relates to a polynucleotide encoding the immunogenic polypeptide and to a host cell comprising the same. Moreover, the present invention relates to kits, methods, and uses related to the immunogenic polypeptide of the invention
A new insight into the suggestion of a possible antigenic role of a member of the 70kD heat shock proteins.
No full textIdentification of new eukaryotic tRNA genes in genomic DNA databases by a multistep weight matrix analysis of transcriptional control regions.
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