1,720,997 research outputs found

    La luce che non c'è ̈.Indicatori di genere in campo formativo

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    Il saggio esplora quali indicatori siano utili e quali disponibili per conoscere un mondo di cui, nonostante tutto, si sa ancora poco, come quello della formazione. Si cerca quindi di mostrare le parti di questo mondo sulle quali possiamo “gettare luce” con le informazioni attualmente in uso

    I processi di mediatizzazione delle sfere pubbliche

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    Vengono esplrati e discussi i processi trasformazione in atto relativamente alle trasformazioni che hanno investito le sfere pubbliche territoriali a causa dei processi di mediatizzazion

    Newsmaking e sfera pubblica mediata: un'introduzione

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    Si presenta, problematizzandolo, lo stato dell'arte sul tema della sfera pubblica e del newsmakin

    Data mining analysis of the PP2A cell cycle axis in mesothelioma patients

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    Mesothelioma is an aggressive tumor that affects thousands of people every year. The therapeutic options for patients are limited; hence, a better understanding of mesothelioma biology is crucial to improve patient survival. To find new molecular targets and therapeutic strategies related to the protein phosphatase 2A (PP2A) network, we analyzed the gene expression of known PP2A inhibitors in mesothelioma patient samples. Our analysis disclosed a general overexpression of all PP2A-negative regulators in mesothelioma patients. Moreover, the expression of ANP32E and CIP2A genes, increased in 16% and 11% of cases, positively correlates with the ones of all the other PP2A regulators and the ones of the main cyclins and CDKs, suggesting the existence of a feed-forward loop that might contribute to the mesothelioma progression via PP2A inactivation. Overall, our study indicates the existence of a strategic and targetable axis between PP2A inhibitors (ANP32E and CIP2A) and cell cycle regulators (cyclin B2/CDK1) and provides a valuable rationale for using a personalized combinational therapy approach to improve mesothelioma patient survival

    Attori e rituali organizzativi

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    Vengono esplorate le dinamiche comunicative e i rituali organizzativi delle redazion

    Disabilita' e lavoro. Costruzione identitaria ed esercizio di cittadinanza

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    il saggio indaga le caratteristiche del binomio disabilità e lavoro in prospettiva inclusiva e nell'orizzonte della costruzione della cittadinanza

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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