133,221 research outputs found

    Energy communities in a distributed-energy scenario: Four different kinds of community arrangements

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    Distributed-energy generation enables a closer link to be established between energy production and energy consumption, but it does not, in itself, necessarily entail any (new) particular role or organization for groups of people. Nevertheless, because of the distributed-energy spread, the phenomenon of so-called energy communities is growing: all over the world, different kinds of groups organized to produce and consume energy are flourishing. In this regard, the term “energy community” is used in a generic sense to refer to heterogeneous phenomena. This work contributes to the study of energy communities by identifying key features that enhance understanding of what energy communities are. Since the literature seems to offer only partial points of view, this chapter intends to contribute to building a new taxonomy of energy communities with which to understand the nature and possible effects of the phenomenon. A first distinction can be drawn between place-based communities and non-place-based ones: in the first case, there is coherence between the community and a specific territory; this does not occur in the second case. Another difference is apparent between communities which form (and operate) only for energy purposes and those which instead add other purposes; in this regard, we can further distinguish between “energy-only communities” and “multi-issue communities”. These two pairs of possibilities give rise to a four-cell matrix: that is, to four main cases of energy communities

    Il web e l'immagine pubblica del territorio

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    Il presente lavoro ha per oggetto l’immagine pubblica del distretto delle Terme Euganee, studiata attraverso l’analisi dei principali siti web dedicati alla comunicazione dell’area e dei siti di prenotazione online. L’obiettivo è valutare le forme di narrazione, le immagini, i racconti del territorio, delle sue risorse e delle strutture ricettive di cui dispone, allo scopo di mettere a disposizione elementi utili al riposizionamento, almeno in termini comunicativi, dell’area

    MeSH term explosion and author rank improve expert recommendations

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    Information overload is an often-cited phenomenon that reduces the productivity, efficiency and efficacy of scientists. One challenge for scientists is to find appropriate collaborators in their research. The literature describes various solutions to the problem of expertise location, but most current approaches do not appear to be very suitable for expert recommendations in biomedical research. In this study, we present the development and initial evaluation of a vector space model-based algorithm to calculate researcher similarity using four inputs: 1) MeSH terms of publications; 2) MeSH terms and author rank; 3) exploded MeSH terms; and 4) exploded MeSH terms and author rank. We developed and evaluated the algorithm using a data set of 17,525 authors and their 22,542 papers. On average, our algorithms correctly predicted 2.5 of the top 5/10 coauthors of individual scientists. Exploded MeSH and author rank outperformed all other algorithms in accuracy, followed closely by MeSH and author rank. Our results show that the accuracy of MeSH term-based matching can be enhanced with other metadata such as author rank

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Mono- and bicyclic analogs of parathyroid hormone-related protein .2. Conformational analysis of antagonists by CD, NMR, and distance geometry calculations

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    The conformation of the three cyclic antagonist analogs of parathyroid hormone-related protein (PTHrP)-(7-34) {[Lys(13), Asp(17)]PTHrP-(7-34)NH2, [Lys(26), ASp(30)]PTHrP-(7-34)NH2, [Lys(13), Asp(17), Lys(26), Asp(30)]PTHrP-(7-34)NH2} is investigated by CD, NMR, and extensive computer simulations in aqueous solution and a TFE:water mixture. The structural analysis of these peptides, designed to stabilize different regions of the sequence in a-helical conformations, is an important step in addressing the correlation between helical content and binding affinity and bioactivity in this hormone-receptor system. Results from CD and NMR spectroscopy of all three analogues in aqueous solution indicate the presence of or-helix only in regions containing a 20-membered lactam ring. Upon addition of TFE, the three analogues display differences in the anticipated increase in helical content. The high-resolution structures produced at 50:50 TFE:water indicate specific differences in the extent and location of the helical regions. These conformations provide insight into the biological profiles of these analogues, reported in the previous manuscript [Bisello et al. (1997) Biochemistry 36, 3293-3299]. Since all three analogues are a-helical in the C-terminal region (residues 25-34 have been previously identified as containing the binding domain) and display similar binding affinities, we conclude that this conformational feature is important for the interaction between the peptide and the receptor. The extent of the helix (toward the N-terminus) and the presence of a hinge in the central region of the peptide play roles in the observed efficacy as measured by antagonism of PTH-stimulated adenylyl cyclase activity. The most active analogue consists of helical segments from residues 13-18 and 20-34, separated by a kink centered at Arg(19)
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