1,721,010 research outputs found
A commentary on the paper: 'Evaluation of spice and herb as phytoderived selective modulators of human retinaldehyde dehydrogenases using a simple <I>in vitro</I> method'
No full text
The S-adenosyl-l-methionine radical enzymes : the lipoic acid synthase and the biotin synthase
No full text
Get PDFSulfane sulfur is a divalent sulfur atom bonded to another sulfur which is very reactive and labile. Compounds containing this reactive sulfur include persulfides, polysulfides, thiosulfate, thiosulfinates, polythionates, and elemental sulfur. Sulfane sulfur appears
in a number of biologically important compounds, including thiocysteine, thiocystine and thiotaurine, products of the cysteine metabolism, as well as glutathione
persulfide. Sulfane sulfur compounds can modify
cysteine residues in proteins via an S-sulfhydration reaction to produce protein persulfides. It has been also
postulated that cysteine persulfides can be incorporated
into proteins during translation. Recently, the sulfane
sulfur compounds, especially the persulfides and polysulfides, have attracted increasing interest due to their
regulatory and antioxidant properties. Compounds containing sulfane sulfur are also regarded as a form of H2S
storage, which can easily release this gasotransmitter in
response to biological signals. Both reactive sulfur species (H2S and sulfane sulfur) always coexist in biological
systems. This review is focused on new findings in the
field of sulfane sulfur’s biological role, and disruption of
its level in some patho/physiological conditions. A few
sulfane sulfur donors with potential applications are presented. In recent years, in parallel to increasing interest
in biological importance of sulfane sulfur, new analytical
methods have been developed for sensitive and reliable
determination of its level in the cells and tissues
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
- …
