169,762 research outputs found
Bio-districts and the territory: evidence from a regression approach
No full textIn recent years the bio-districts have been considerably spread in Italy. The bio-district can be defined as a locally rooted multifunctional project with the involvement of farms and institutions. Our research aims at assessing potential relations between territorial, socio-economic features and the presence of bio-districts in an area, by means of a logit regression analysis at municipal scale in Italy.
Data have been collected from several sources, among which ISTAT digital databases. Main results show as farms with diversification activities and the presence of Local Action Groups are factors related to the rising of bio-districts in a territory. Moreover, the study highlights the role of bio-districts in disadvantageous and mountain areas, in developing effective territorial governance. In terms of policy implication, CAP 2023-2027 can constitute the ideal bench for testing bio-districts function playing a crucial role in reaching the objective set by the Farm to Fork strategy
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Environmental agency, moral reasoning, and moral disengagement in adults
No full textTo assess the relationships between environmental agency, prosocial moral reasoning, and civic moral disengagement, 544 community-dwelling adults were administered the image-based Environmental Agency Scale (EAS), the Prosocial Moral Reasoning Objective Measure (PROM), and the Civic Moral Disengagement Scale (CMDS). The EAS Agentic Self and Agentic Other dimensions proved to be reliable measures and showed adequate factor validity. Mean/median score comparisons between EAS Agentic Self Scale and Agentic Other Scale scores indicated that participants viewed society-level actions as more relevant than individual-level actions when environment defense is at issue. Partial correlation analysis results showed that environmental agentic self was grounded in individual differences in prosocial moral reasoning. Civic moral disengagement yielded negative associations with EAS Agentic Other Scale scores, providing further support to the relevance of moral disengagement process in environmental sensitivity. These results may improve our understanding of environmental agency and its connections with prosocial moral reasoning and moral disengagement.To assess the relationships between environmental agency, prosocial moral reasoning, and civic moral disengagement, 544 community-dwelling adults were administered the image-based Environmental Agency Scale (EAS), the Prosocial Moral Reasoning Objective Measure (PROM), and the Civic Moral Disengagement Scale (CMDS). The EAS Agentic Self and Agentic Other dimensions proved to be reliable measures and showed adequate factor validity. Mean/median score comparisons between EAS Agentic Self Scale and Agentic Other Scale scores indicated that participants viewed society-level actions as more relevant than individual-level actions when environment defense is at issue. Partial correlation analysis results showed that environmental agentic self was grounded in individual differences in prosocial moral reasoning. Civic moral disengagement yielded negative associations with EAS Agentic Other Scale scores, providing further support to the relevance of moral disengagement process in environmental sensitivity. These results may improve our understanding of environmental agency and its connections with prosocial moral reasoning and moral disengagement
“One-pot synthesis of a,b-unsatured caroxylic acids via tandem Wittig olefination-hydrolysis reaction under combined microwave and ultrasound irradiation”.
No full text
Multidimensional Prognostic Index (MPI) in an outpatient setting: Mortality and hospitalizations
No full textRole of the JP45-Calsequestrin Complex on Calcium Entry in Slow Twitch Skeletal Muscles
No full textWe exploited a variety of mouse models to assess the roles of JP45-CASQ1 (CASQ, calsequestrin) and JP45-CASQ2 on calcium entry in slow twitch muscles. In flexor digitorum brevis (FDB) fibers isolated from JP45-CASQ1-CASQ2 triple KO mice, calcium transients induced by tetanic stimulation rely on calcium entry via La3+- and nifedipine-sensitive calcium channels. The comparison of excitation-coupled calcium entry (ECCE) between FDB fibers from WT, JP45KO, CASQ1KO, CASQ2KO, JP45-CASQ1 double KO, JP45-CASQ2 double KO, and JP45-CASQ1-CASQ2 triple KO shows that ECCE enhancement requires ablation of both CASQs and JP45. Calcium entry activated by ablation of both JP45-CASQ1 and JP45-CASQ2 complexes supports tetanic force development in slow twitch soleus muscles. In addition, we show that CASQs interact with JP45 at Ca2+ concentrations similar to those present in the lumen of the sarcoplasmic reticulum at rest, whereas Ca2+ concentrations similar to those present in the SR lumen after depolarization-induced calcium release cause the dissociation of JP45 from CASQs. Our results show that the complex JP45-CASQs is a negative regulator of ECCE and that tetanic force development in slow twitch muscles is supported by the dynamic interaction between JP45 and CASQs
Mitomycin C in highly myopic eyes - Author reply
No full textOphthalmology. 2005 Feb;112(2):208-18; discussion 219.
Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes.
Gambato C, Ghirlando A, Moretto E, Busato F, Midena E.
SourceRefractive Surgery Service and Antimetabolite Therapy Research Unit, Department of Ophthalmology, University of Padova, Padova, Italy.
Abstract
PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH) after photorefractive keratectomy (PRK) in highly myopic eyes.
DESIGN: Prospective, double-masked, randomized clinical trial.
PARTICIPANTS: Seventy-two eyes of 36 patients affected by high (>7 diopters) myopia.
METHODS: In each patient, one eye was randomly assigned to PRK with intraoperative topical 0.02% mitomycin C application, and the fellow eye was treated with a placebo. Postoperatively, mitomycin C-treated eyes received artificial tears (3 times daily, tapered in 3 months), whereas the fellow eye was treated with fluorometholone sodium 2% and artificial tears (3 times daily, tapered in 3 months).
MAIN OUTCOME MEASURES: Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), contrast sensitivity, manifest refraction, and biomicroscopy. Contrast sensitivity was determined using the Pelli-Robson chart. Corneal confocal microscopy documented CWH.
RESULTS: Mean follow-up was 18 months (range, 12-36). No side effects or toxic effects were documented. At 12-month follow-up examination, UCVAs (logarithm of the minimum angle of resolution) were 0.4+/-0.48 and 0.5+/-0.53 (P = .03) in mitomycin C-treated eyes and corticosteroid-treated eyes, respectively. At 1 year, corneal haze developed in 20% of corticosteroid-treated eyes, versus 0% of mitomycin C-treated eyes. At 12, 24, and 36 months, corneal confocal microscopy showed activated keratocytes and extracellular matrix significantly more evident in untreated eyes (Ps = 0.004, 0.024, and 0.046, respectively).
CONCLUSION: Topical intraoperative application of 0.02% mitomycin C can reduce haze formation in highly myopic eyes undergoing PRK.
Comment in
Ophthalmology. 2006 Feb;113(2):357; author reply 357-8
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Prosthetic Indirect Composites: Solubility, Absorption and Color’s Variation
No full textTo evaluate solubility, absorption and color’s variation in indirect composites
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