1,721,124 research outputs found

    X-linked Wiskott-Aldrich syndrome in a girl.

    No full text
    Comment on X inactivation in females with X-linked disease. [N Engl J Med. 1998] X-linked Wiskott-Aldrich syndrome in a girl. [N Engl J Med. 1998

    ISMSC2019: 14th International Symposium of Macrocyclic and Supramolecular Chemistry

    Full text link
    This special issue of Supramolecular Chemistry is dedicated to the 14th International Symposium of Macrocyclic and Supramolecular Chemistry (ISMSC2019), which was successfully held in Lecce, Italy, from 2 to 6 June 2019. The symposium was organised by Politecnico di Milano and Fondazione Politecnico di Milano, and chaired by Pierangelo Metrangolo, Francesca Baldelli Bombelli, and Giancarlo Terraneo. Following a quite long tradition, the symposium provided the great opportunity to discuss the forefront research in macrocyclic and supramolecular chemistry. More than 700 international scientists, from 43 different countries and from diverse research environments, gathered in Lecce to attend the symposium. It was a unique occasion for graduate students, postdocs and scientists to exchange ideas, to discuss innovative and emerging results and to promote inter-discipline collaborations

    Differential HFE allele expression in hemochromatosis heterozygotes

    No full text
    Comment on: Differential HFE allele expression in hemochromatosis heterozygotes. [Gastroenterology. 2000

    Photoluminescent nanocluster-based probes for bioimaging applications

    Full text link
    In the continuous search for versatile and better performing probes for optical bioimaging and biosensing applications, many research efforts have focused on the design and optimization of photoluminescent metal nanoclusters. They consist of a metal core composed by a small number of atoms (diameter < 2–3 nm), usually coated by a shell of stabilizing ligands of different nature, and are characterized by molecule-like quantization of electronic states, resulting in discrete and tunable optical transitions in the UV–Vis and NIR spectral regions. Recent advances in their size-selective synthesis and tailored surface functionalization have allowed the effective combination of nanoclusters and biologically relevant molecules into hybrid platforms, that hold a large potential for bioimaging purposes, as well as for the detection and tracking of specific markers of biological processes or diseases. Here, we will present an overview of the latest combined imaging or sensing nanocluster-based systems reported in the literature, classified according to the different families of coating ligands (namely, peptides, proteins, nucleic acids, and biocompatible polymers), highlighting for each of them the possible applications in the biomedical field. Graphical abstract: [Figure not available: see fulltext.

    Going Beyond Counting First Authors in Author Co-citation Analysis

    Full text link
    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Photochemistry of transition metal complexes (2019-2020)

    No full text
    This Chapter aims to summarise the major advances achieved over 2019 and 2020 in the field of photochemistry and photocatalysis by transition metal compounds. In the last years, one of the central research themes has been the development of efficient photocatalytic complexes based on earth-abundant metals as a potential eco-friendly, resource-efficient, and sustainable photochemical approach. Nevertheless, second- and third-row metal complexes still represent key building blocks in the design of new photocatalysts in organic transformations, biomedical applications, as well as in green chemistry fields

    Variations on the Author

    Full text link
    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

    Full text link
    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

    Full text link
    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods
    corecore