1,721,041 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
EFFECTS OF LOW-DOSES OF TIADENOLO IN DIABETIC AND NON-DIABETIC PATIENTS WITH VARIOUS TYPES OF HYPERLIPOPROTEINEMIAS
No full textVariations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Characterization of insulin degrading activity in subcellular fractions of human monocytes
No full textInsulin degrading activity (IDA) was studied in subcellular fractions from homogenized human mononuclear cells. More than 90% (mean ± SD >> 94.1% ± 4.0) of total IDA was found in the soluble fraction (100,000 x g supernatant) of monocytes and it was completely inhibited by protease inhibitors such as Bacitracin (1 mg/ml) and NEM (1 mM). IDA was time-, temperature- and pH-dependent, being completely inhibited at 4°C and being maximal at pH 7.0-7.5; its Km for insulin was 1.9 x 10-7 M. The partially purified insulin degrading enzyme had a molecular weight of 120,000. When A14-125I-insulin was incubated with purified IDA a variety of degradative products were identified by HPLC, in addition to 125I and a small percentage of intact insulin. Different elution patterns were observed after incubating with IDE monoiodinated A19-, B16, and B26-insulin. In conclusion, IDA from human mononuclear cells has characteristics similar to those of other IDA previously reported in typical insulin target tissues. Mononuclear cells therefore represent a suitable model for studying insulin degradation in humans
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