1,720,961 research outputs found
Nanosurfaces Scaffold and Magnetic Nanoparticles to Direct the Neuronal Growth Process: Future Strategies for Peripheral Nerve Regeneration
Full text linkPeripheral nerves injuries are common lesions than often cause loss of function and poor outcome. Current strategies to nerve repair take advantage by microsurgical suture. In case of severe nerve gap (>50mm),the gold standard remains the autologous graft. Recently, researchers focused on two main areas of investigation: the role of the interaction between cells with the extracellular membrane (ECM )and the forces acting during axonal elongation
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Treatment of Scaphoid Waist Nonunion Using Olecranon Bone Graft and Stryker Asnis Micro Cannulated Screw: A Retrospective Study-80 Case Studies and 6 Years of Follow-Up
No full textBackground Screw fixation and bone grafting are the gold standard for scaphoid waist nonunion without avascular necrosis. Question/Purpose Assesses the scaphoid waist nonunion healing rate with use of an uncommon cancellous bone graft (olecranon) and an unusual fixation system (Asnis Micro Cannulated Screw System; Stryker Inc., Kalamazoo, MI, USA). Material and Methods A series of 102 consecutive patients were treated for scaphoid waist nonunion (without deformity). Of these, 80 patients subjected to clinical (Modified Mayo Wrist Score (MMWS), Jamar hydraulic dynamometer) and radiographic examination before and after surgery were evaluated. Ipsilateral olecranon cancellous bone graft and the ASNIS Micro 3.0-mm diameter screw, were used. The average follow up was 6 years (min 3; max 10). Results Radiographic consolidation was achieved in 90% of patients; dorsal intercalated segment instability (DISI) deformities were corrected in 71.4% of cases. Ninety percent improved the range of motion of the wrist and grip strength. All patients showed a significant reduction of peak force in the operated hand. In 6.25% we observed clinical and radiographic screw head-trapezium impingement. Twenty-six patients developed a degenerative wrist sign. The MMWS yielded 68 optimal, 8 good, and 4 bad results. Conclusions To treat scaphoid waist nonunions without misalignment, low-profile headed screw and olecranon bone graft allowed a high consolidation rate with positive results to long-term follow-up. The Asnis Micro 3.0 mm diameter screw may be a suitable option for treating scaphoid waist nonunion. Level of Evidence IV
SUPERFICI NANOSTRUTTURATE E RIGENERAZIONE NERVOSA PERIFERICA
No full textIl gold standard nel trattamento delle grosse perdite di sostanza nervosa rimane l’innesto autologo che, con la presenza cellule di Schwann, offre fattori neurotro ci e substrati d’adesione per la crescita asso- nale. Per i limiti di tale metodica (danno al sito donatore, doppio accesso chirurgico ed indisponibilità d’ingenti quantità d’innesti) sono state proposte delle alternative come la tubulizzazione (biologica o sintetica). Recentemente è stata data importanza all’interazione fra le cellule (nervose e gliali) e gli sti- moli sici e chimici provenienti dall’ambiente extracellulare. L’ingegneria tissutale è oggi in grado di produrre scaffold con strutturazione super ciale delle dimensione dei nanometri in grado di riprodurre le caratteristiche della matrice extracellulare (ECM). La versatilità con cui possono essere prodotte que- ste super ci e la loro possibile funzionalizzazione con molecole biologiche (peptidi/proteine, fattori di crescita, ecc.), può essere applicata nel trattamento delle perdite di sostanza nervosa (>30 mm) con l’o- biettivo di realizzare un device a struttura tubulare con un’adeguata interfaccia nervo-scaffold, essibile, biocompatibile, e non immunogenica.Today, the treatment of big nerve gaps is the autologous nerve graft (with Schwann cells, it provides neurotropic factors and adhesion substrates that aid the axonal growth). The limits of this technique are the donor side damage, the need of double surgical access and unavailability of large amounts of grafts. Some authors proposed alternatives like tubulization (biological or synthetic tubes). Recently, the rese- archers focus on the interaction between the cells (nerve and glial cells) and the physical and chemical signals risen from the extracellular environment.
Tissue engineering is able to produce scaffolds with some degree of micro/nano topographical noise that reproduce the directional stimuli determined by the extracellular matrix (ECM). Moreover these gratings can be functionalized with biological molecules, peptides, proteins, growth factors, ecc.
We can consider these new surfaces like new possibilities for successful implant strategies in the context of peripheral nerve-regeneration devices, especially for the big nerve gap (>30 mm)
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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