1,721,008 research outputs found
Clinical and endocrine effects of ovulation induction with FSH and HCG supplementation in low responders in the mid-follicular phase
No full text“Effetto della prematura elevazione del progesterone nell’efficienza riproduttiva dopo PMA” S I F E S 1999: 118
No full text“Paracrine and endocrine effect of profound LH suppression in ART” E S G O I 2001 – C I C Edizioni Internazionali 359 – 64
No full text“Impiego dell’antagonista del Gn RH ( Cetrorelix 9 nelle procreazioni medicalmente assistite ( PMA ) S I F E S e M R 2000: 201
No full textGonadotropin-releasing hormone antagonists increase follicular fluid insulin-like growth factor-I and vascular endothelial growth factor during ovarian stimulation cycles.
No full textThe aim of the present study was to investigate the effect of gonadotropin-releasing hormone (GnRH) antagonists (GnRH-ant) on follicular fluid (FF) insulin-like growth factor-I (IGF-I) and FF vascular endothelial growth factor (VEGF) levels. Sixty women undergoing assisted reproduction were randomized and assigned to two different GnRH analog regimens: GnRH agonist (GnRH-a) and GnRH-ant. FF VEGF and FF IGF-I concentrations were significantly increased in the patients treated with GnRH-ant (ρ<0.001). In the same patients we observed a statistically significant reduction in serum luteinizing hormone (LH) and estradiol (E2 ) levels (ρ<0.001 and ρ<0.05, respectively), FF E2 and FF androstenedione levels (ρ<0.05 and ρ<0.001, respectively), as well as a reduction in the number of pregnancies although this was not statistically significant. In the GnRH-ant group, FF VEGF levels were positively correlated with FF IGF-I levels, and both were negatively correlated with serum LH levels. The increase in FF IGF-I and FF VEGF levels in women treated with GnRH-ant could be explained by a deleterious follicular environment in response to profound suppression of LH and E2 levels
“Steroidi follicolari e maturità ovocitaria nelle PMA.” Medicina e biologia riproduttiva:stato dell,’arte alle soglie della legislazione. Puglia Grafica Sud Bari Ed. 1999:33-7
No full textFollicular fluid vascular endothelial growth factor concentrations are increased during GnRH antagonist/FSH ovarian stimulation cycles.
No full textBackground: The aim of this study was to investigate the effect of GnRH antagonists (GnRH-ant) on follicular fluid vascular endothelial
growth factor (FF VEGF).
Methods: Sixty women undergoing assisted reproduction were randomised (computer-generated randomisation list) and assigned to two
different GnRH analogue regimens: GnRH agonist (GnRH-a) (Group A; n = 30) and GnRH-ant (Group B; n = 30).
Results: Mean (S.D.) FF VEGF concentrations were 1598 612 pg/mL and 2906 1558 pg/mL for Groups A and B, respectively
( p < 0.001). In the women treated with GnRH-ant, we found a statistically significant reduction in serum LH levels (1.72 0.74 IU/L in
Group A versus 0.93 0.43 IU/L in Group B, p < 0.001), in serum oestradiol (E2) levels (1562.1 410.7 pg/mL in Group A versus
1214.67 779.9 pg/mL in Group B, p < 0.05), in FF E2 levels (1146 593 ng/mL in Group A versus 621 435 ng/mL in Group B,
p < 0.05), and in FF androstenedione levels (136 55 ng/mL in Group A versus 78 31 ng/mL in Group B, p < 0.001), as well as a
reduction in the number of pregnancies, though not statistically significant (23.3% in Group A versus 16.6% in Group B).
Conclusion: The increase in FF VEGF levels in women treated with GnRH-ant might be explained by a suppression of LH and E2 levels
Mid follicular LH levels and reproductive outcome in women receiving GnRHa depot or daily
No full text“Increased follicular vascolar endothelian growth factor ( VEGF ) as parocrine reaction to Hostile environment in profound Gn RH agonist suppression in ART” 57th Meeting of the American Society for Reproduction Medicine. Fertil Steril 2001: S 93
No full text“LH endogeno e outcome riproduttivo nelle PMA” Giornale Italiano di Ostetricia e Ginecologia C I C Edizioni Internazionali 2001: 94 – 6
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