1,720,996 research outputs found
Time-resolved fluorescence study during denaturation and renaturation of curcumin-myoglobin complex
No full textCurcumin influences the transition point, the concentration of denaturant required to effect 50percent of the total change, of myoglobin denaturation. Curcumin enhances absorbance of myoglobin at 280nm with a binding constant K=3.0×104M-1 whereas fluorescence of curcumin is quenched by myoglobin with a Stern-Volmer association constant of 2.5×105M-1. Unfolding process of myoglobin-curcumin induces a recovery in fluorescence lifetime loss. The gain in time-resolved fluorescence lifetime during unfolding has been again lost during refolding of curcumin-myoglobin complex by dilution process suggesting partial reversibility of unfolding process for both myoglobin and curcumin-myoglobin complex. © 2012 Elsevier B.V.Abou-Zied OK, 2008, J AM CHEM SOC, V130, P10793, DOI 10.1021-ja8031289; Baglole KN, 2005, J PHOTOCH PHOTOBIO A, V173, P230, DOI 10.1016-j.jphotochem.2005.04.002; Barakat C., 2012, LUMINESCENCE 0207, DOI [10.1002-bio.2354, DOI 10.1002-BIO.2354]; Barakat C., 2010, KALAHANDI RENAISSANC, VV, P64; Barik A, 2003, PHOTOCHEM PHOTOBIOL, V77, P597, DOI 10.1562-0031-8655(2003)0770597:PSOBOC2.0.CO;2; Barik A, 2007, CHEM PHYS LETT, V436, P239, DOI 10.1016-j.cplett.2007.01.006; Benesi M. L., 1949, J AM CHEM SOC, V71, P2703; Bisht S., 2007, J NANOBIOTECHNOL, V5, P1; Bourassa P, 2010, J PHYS CHEM B, V114, P3348, DOI 10.1021-jp9115996; Cantor C.R., 1980, BIOPHYSICAL CHEM 2; CHIGNELL CF, 1994, PHOTOCHEM PHOTOBIOL, V59, P295, DOI 10.1111-j.1751-1097.1994.tb05037.x; Chowdhry B, 1997, J CHEM EDUC, V74, P236; Clifford NW, 2008, J MATER CHEM, V18, P162, DOI 10.1039-b715100d; Connors K. A., 1987, MEASUREMENTS MOL COM; Creighton T. E., 1993, PROTEIN STRUCTURE; Creighton T. E., 1992, PROTEIN FOLDING; DAUTREVA.M, 1969, EUR J BIOCHEM, V11, P267, DOI 10.1111-j.1432-1033.1969.tb00769.x; Devasenam T, 2003, PHARM RES, V27, P133; DILL KA, 1991, ANNU REV BIOCHEM, V60, P795, DOI 10.1146-annurev.biochem.60.1.795; EFTINK MR, 1994, BIOPHYS J, V66, P482; EVANS SV, 1990, J MOL BIOL, V213, P885, DOI 10.1016-S0022-2836(05)80270-0; Feng W, 2006, J FLUORESC, V16, P53; GOLDBERG ME, 1991, TRENDS BIOCHEM SCI, V16, P358, DOI 10.1016-0968-0004(91)90148-O; Jones CM, 1997, J CHEM EDUC, V74, P1306; Jovanovic SV, 2001, J AM CHEM SOC, V123, P3064, DOI 10.1021-ja003823x; Jovanovic SV, 1999, J AM CHEM SOC, V121, P9677, DOI 10.1021-ja991446m; Leung MHM, 2008, LANGMUIR, V24, P5672, DOI 10.1021-la800780w; Lin YG, 2007, CLIN CANCER RES, V13, P3423, DOI 10.1158-1078-0432.CCR-06-3072; Pace C N, 1986, Methods Enzymol, V131, P266; Pace N.C., 1989, PROTEIN STRUCTURE PR; Patra D, 2012, LUMINESCENCE, V27, P11, DOI 10.1002-bio.1313; Patra D, 2011, SPECTROCHIM ACTA A, V79, P1034, DOI 10.1016-j.saa.2011.04.016; Patra D, 2011, SPECTROCHIM ACTA A, V79, P1823, DOI 10.1016-j.saa.2011.05.064; Patra D., PHOTOCHEM P IN PRESS; Privalov P.L., 1990, BIOCH MOL BIOL, V25, P281; PUETT D, 1973, J BIOL CHEM, V248, P4623; Rankin MA, 2004, SUPRAMOL CHEM, V16, P513, DOI 10.1080-10610270412331283583; SCHECHTE.AN, 1968, J MOL BIOL, V35, P567, DOI 10.1016-S0022-2836(68)80015-4; Schmid F.X., 1989, PROTEIN STRUCTURE PR; SHARMA OP, 1976, BIOCHEM PHARMACOL, V25, P1811, DOI 10.1016-0006-2952(76)90421-4; SRIVASTAVA KC, 1995, PROSTAG LEUKOTR ESS, V52, P223, DOI 10.1016-0952-3278(95)90040-3; Sun YM, 2002, ORG LETT, V4, P2909, DOI 10.1021-ol0262789; TANFORD C, 1964, J AM CHEM SOC, V86, P2050, DOI 10.1021-ja01064a028; Tourkina E, 2004, AM J RESP CELL MOL, V31, P28, DOI 10.1165-rcmb.2003-03540C; Vemula PK, 2006, J AM CHEM SOC, V128, P8932, DOI 10.1021-ja062650u; WARE WR, 1962, J PHYS CHEM-US, V66, P455, DOI 10.1021-j100809a02044
An analysis of packet sampling in the frequency domain
No full textPacket sampling techniques introduce measurement errors that should be carefully handled in order to correctly characterize the network behavior. In the literature several works have studied the statistical properties of packet sampling and the way it should be inverted to recover the original network measurements. Here we take the new direction of studying the spectral properties of packet sampled traffic. A novel technique to model the impact of packet sampling is proposed based on a theoretical analysis of network traffic in the frequency domain. Moreover, a real-time algorithm is also presented to detect the spectrum portion of the network traffic that can be restored once packet sampling has been applied. Preliminary experimental results are reported to validate the proposed approach
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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