99,143 research outputs found
Chen, M.-J., Han, Y.-R., Hu, J.-X., Liu, Y.-J. & Huang, B. (2023) Tolypocladium rhizomatum sp. nov.: an endophytic species isolated from the rhizome of Polygonatum cyrtonema. Phytotaxa 606 (3): 201-210.
No full textChen, M.-J., Han, Y.-R., Hu, J.-X., Liu, Y.-J., Huang, B. (2023): Chen, M.-J., Han, Y.-R., Hu, J.-X., Liu, Y.-J. & Huang, B. (2023) Tolypocladium rhizomatum sp. nov.: an endophytic species isolated from the rhizome of Polygonatum cyrtonema. Phytotaxa 606 (3): 201-210. Phytotaxa 607 (1): 114-114, DOI: 10.11646/phytotaxa.607.1.10, URL: http://dx.doi.org/10.11646/phytotaxa.607.1.1
A common HLA-DPA1 variant is associated with hepatitis B virus infection but fails to distinguish active from inactive Caucasian carriers
No full textBackground and Aims: Chronic infection with the hepatitis B virus (HBV) is a major health issue worldwide. Recently, single nucleotide polymorphisms (SNPs) within the human leukocyte antigen (HLA)-DP locus were identified to be associated with HBV infection in Asian populations. Most significant associations were observed for the A alleles of HLA-DPA1 rs3077 and HLA-DPB1 rs9277535, which conferred a decreased risk for HBV infection. We assessed the implications of these variants for HBV infection in Caucasians.
Methods: Two HLA-DP gene variants (rs3077 and rs9277535) were analyzed for associations with persistent HBV infection and with different clinical outcomes, i.e., inactive HBsAg carrier status versus progressive chronic HBV (CHB) infection in Caucasian patients (n = 201) and HBsAg negative controls (n = 235).
Results: The HLA-DPA1 rs3077 C allele was significantly associated with HBV infection (odds ratio, OR = 5.1, 95% confidence interval, CI: 1.9–13.7; p = 0.00093). However, no significant association was seen for rs3077 with progressive CHB infection versus inactive HBsAg carrier status (OR = 2.7, 95% CI: 0.6–11.1; p = 0.31). In contrast, HLA-DPB1 rs9277535 was not associated with HBV infection in Caucasians (OR = 0.8, 95% CI: 0.4–1.9; p = 1).
Conclusions: A highly significant association of HLA-DPA1 rs3077 with HBV infection was observed in Caucasians. However, as a differentiation between different clinical courses of HBV infection was not possible, knowledge of the HLA-DPA1 genotype cannot be translated into personalized anti-HBV therapy approaches
sj-pdf-1-han-10.1177_15589447231174482 – Supplemental material for Anterior Interosseus to Ulnar Motor Nerve Transfers: A Canadian Perspective
No full textSupplemental material, sj-pdf-1-han-10.1177_15589447231174482 for Anterior Interosseus to Ulnar Motor Nerve Transfers: A Canadian Perspective by Spencer B. Chambers, Kitty Y. Wu, Douglas C. Ross and Joshua A. Gillis in HAND</p
15 años de alfabetización en información: investigación internacional recogida en LISA, ERIC y SSCI entre 1990 y 2005
No full textSe presenta el alcance de la investigación internacional en Alfabetización en Información (ALFIN)entre los años 1990 y 2005 a partir del análisis de las publicaciones recogidas en tres de las principales bases de datos internacionales que cubren el tema: LISA, ERIC y SSCI. Se ha analizado la actividad investigadora del periodo, la tipología documental, idioma, autores más productivos y revistas más
utilizadas. Por otro lado, y a través de una metodología de análisis de contenido, se han categorizado los trabajos de los diez autores más productivos, encontrando en ellos la progresión temática lógica de un área en desarrollo. Otros resultados indican el predominio de trabajos anglosajones así como el incremento exponencial de la producción a lo largo del periodo estudiado.Publicad
The relationship between civic attitudes and voting intention : an analysis of vocational upper secondary schools in England and Singapore
No full textFrom 2009 to 2011, a team from the Centre for Learning and Life Chances in Knowledge Economies and Societies carried out a mixedmethods study of young people in England and Singapore. With regard to civic attitudes, the study showed that there was a greater sense of political self-efficacy and collective (school) efficacy in Singapore than in England. In addition, the group in Singapore scored higher on future voting relative to the group in England. Further, while both political self-efficacy and collective (school) efficacy were correlated with future voting in England, only the latter was correlated in the case of Singapore. For some, the results may seem counter-intuitive. The article reflects on these results, particularly those relating to democratic outcomes
Flexural performance of reinforced concrete beams strengthened with strain-hardening cementitious composite and high strength
No full textThe cracking and strength improvement in beams are one of main issues in the area of architecture and civil engineering. This paper presents the experimental and numerically predictive studies on the flexural performance of reinforced concrete (RC) beams strengthened with a strain-hardening cementitious composite (SHCC) and high strength reinforcing steel bar (HSRS bar) as a new strengthening method for beams. In order to investigate the effects of SHCC and HSRS bar on the control of cracking and load bearing capacity, four types of beam specimens were manufactured and a series of flexural bending tests were performed. The test results showed that the crack width can be controlled by applying SHCC and the load-bearing capacity of beams improved by applying the SHCC and HSRS bar
Boron-mediated directed aromatic C–H hydroxylation
No full textTransition metal-catalysed C–H hydroxylation is one of the most notable advances in synthetic chemistry during the past few decades and it has been widely employed in the preparation of alcohols and phenols. The site-selective hydroxylation of aromatic C–H bonds under mild conditions, especially in the context of substituted (hetero)arenes with diverse functional groups, remains a challenge. Here, we report a general and mild chelation-assisted C–H hydroxylation of (hetero)arenes mediated by boron species without the use of any transition metals. Diverse (hetero)arenes bearing amide directing groups can be utilized for ortho C–H hydroxylation under mild reaction conditions and with broad functional group compatibility. Additionally, this transition metal-free strategy can be extended to synthesize C7 and C4-hydroxylated indoles. By utilizing the present method, the formal synthesis of several phenol intermediates to bioactive molecules is demonstrated
Metal-free cascade boron–heteroatom addition and alkylation with diazo compounds
No full textTransition metal-catalyzed carbene transfer reaction is one of the most notable advances for C−C bond formation reactionsduring the past decade, which has been widely employed in the preparation of C3-substituted indoles. Here, we described an efficient example of catalyst- and metal-free aminoboration of alkynes and C[sbnd]C bond formation with diazo compounds to produce C3-substituted indoles. Diverse alkynylanilines and diazo compounds can be utilized for this tandem transformation under mild reaction conditions, resulting in broad functional group compatibility. Additionally, this metal-free strategy can be extended to construct substituted benzofurans
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