2,705 research outputs found

    B. Forsberg ex librise

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    http://www.lib.unideb.huDebreceni Egyetem Egyetemi és Nemzeti KönyvtárDombos tájban füstölgő kéményű házikó, mögötte óriási festőpaletta, jobbra elöl a földből fatörzsként kiálló ecset. Alul felirat: Ex libris B. Forsberg. A kép hátulján B. Forsberg '31 felirat.metszetB. Forsber

    Modulation of nuclear lamin-chromatin interactions by external cues

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    The three-dimensional (3D) organization of chromatin in the mammalian cell nucleus plays an important role in the regulation of gene expression. In her Ph.D. thesis, Anna Frida Forsberg has investigated the impact of distinct stimuli on how structural proteins of the nucleus, A- and B-type lamins, participate in 3D genome organization. Identification of genome domains interacting with A- and B-type lamins by chromatin immunoprecipitation shows that in liver cancer cells, A- and B-type lamins associate with both overlapping and distinct domains. Treatment with Cyclosporin A, an immunosuppressive drug which affects transcription factor binding to chromatin, has little effect on chromatin interactions with B-type lamins; in contrast, interactions with A-type lamins are for the most part lost or instead switch to B-type lamins. Fluorescence in situ hybridization shows that genomic domains that gain lamin B are repositioned towards the nuclear periphery, yet without major changes in gene expression. Forsberg also investigated how 24-h (circadian) rhythms affect lamin-chromatin interactions in mouse liver. Strikingly, most of these interactions are stable throughout the circadian cycle. Nevertheless, several genome regions display rhythmic interactions with nuclear lamins, with defined periods of 12, 18, 24 or 30 h. Such periodic lamin-chromatin interactions are however surprisingly independent of changes in the expression of circadian genes. The findings altogether show that A- and B-type nuclear lamins dynamically associate with common but also distinct parts of the genome to modulate 3D genome architecture in response to specific cues

    Estimativa de erosão em clareiras através da mudança do relevo do solo por meio de pinos.

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    Este trabalho objetivou estimar a perda de solo pela mudança no relevo do solo avaliado através da variação da superfície referenciada em pinos metálicos, assim como, sua relação com os processos erosivos e com as propriedades físicas e o carbono.PI3 - Análise de sensibilidade ambiental, modelagem e previsão de impactos. Coordenador Geral: Bruce R. Forsberg

    Taming Data Caches for Predictable Execution on GPU-based SoCs

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    Heterogeneous SoCs (HeSoCs) typically share a single DRAM between the CPU and GPU, making workloads susceptible to memory interference, and predictable execution troublesome. State-of-the art predictable execution models (PREM) for HeSoCs prefetch data to the GPU scratchpad memory (SPM), for computations to be insensitive to CPU-generated DRAM traffic. However, the amount of work that the small SPM sizes allow is typically insufficient to absorb CPU/GPU synchronization costs. On-chip caches are larger, and would solve this issue, but have been argued too unpredictable due to self-evictions. We show how self-eviction can be minimized in GPU caches via clever managing of prefetches, thus lowering the performance cost, while retaining timing predictability

    Utvärdering av effekterna från UU Innovations förstudiemedel

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    Uppsala Universitet Innovation (UUI) har under 2018 gett i uppdrag åt Petter B. Forsberg påAvdelningen för Industriell teknik vid Uppsala universitet att utvärdera effekterna av s.k.förstudiemedel. Med förstudiemedel avses en finansieringsform för att initiera ett mindresamarbetsprojekt mellan universitetsforskare och organisationer utanför akademin. Underhösten 2018 har därför ett antal intervjuer genomförts med forskare och företagsre-presentanter, vilket sedan resulterat i den utvärdering som här presenteras

    HEROv2: Full-Stack Open-Source Research Platform for Heterogeneous Computing

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    Heterogeneous computers integrate general-purpose host processors with domain-specific accelerators to combine versatility with efficiency and high performance. To realize the full potential of heterogeneous computers, however, many hardware and software design challenges have to be overcome. While architectural and system simulators can be used to analyze heterogeneous computers, they are faced with unavoidable compromises between simulation speed and performance modeling accuracy. In this work we present HEROv2, an FPGA-based research platform that enables accurate and fast exploration of heterogeneous computers consisting of accelerators based on clusters of 32-bit RISC-V cores and an application-class 64-bit ARMv8 or RV64 host processor. HEROv2 allows to seamlessly share data between 64-bit host s and 32-bit accelerators and comes with a fully open-source on-chip network, a unified heterogeneous programming interface, and a mixed-data-model, mixed-ISA heterogeneous compiler based on LLVM. We evaluate HEROv2 in four case studies from the application level over toolchain and system architecture down to accelerator microarchitecture. We demonstrate how HEROv2 enables effective research and development on the full stack of heterogeneous computing. For instance, the compiler can tile loops and infer data transfers to and from the accelerators, which leads to a speedup of up to 4.4 x compared to the original program and in most cases is only 15% slower than a handwritten implementation, which requires 2.6 x more code

    Utvärdering av effekterna från UU Innovations förstudiemedel [Elektronisk resurs]

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    Uppsala Universitet Innovation (UUI) har under 2018 gett i uppdrag åt Petter B. Forsberg påAvdelningen för Industriell teknik vid Uppsala universitet att utvärdera effekterna av s.k.förstudiemedel. Med förstudiemedel avses en finansieringsform för att initiera ett mindresamarbetsprojekt mellan universitetsforskare och organisationer utanför akademin. Underhösten 2018 har därför ett antal intervjuer genomförts med forskare och företagsre-presentanter, vilket sedan resulterat i den utvärdering som här presenteras.</p

    HePREM: A Predictable Execution Model for GPU-based Heterogeneous SoCs

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    The ever-increasing need for computational power in embedded devices has led to the adoption heterogeneous SoCs combining a general purpose CPU with a data parallel accelerator. These systems rely on a shared main memory (DRAM), which makes them highly susceptible to memory interference. A promising software technique to counter such effects is the Predictable Execution Model (PREM). PREM ensures robustness to interference by separating programs into a sequence of memory and compute phases, and by enforcing a platform-level schedule where only a single processing subsystem is permitted to execute a memory phase at a time. This article demonstrates for the first time how PREM can be applied to heterogeneous SoCs, based on a synchronization technique for memory isolation between CPU and GPU plus a compiler to transform GPU kernels into PREM-compliant codes. For compute bound GPU workloads sharing the DRAM bandwidth 50/50 with the CPU we guarantee near-zero timing varibility at a performance loss of just 59 percent, which is one to two orders of magnitude smaller than the worst case we see for unmodified programs under memory interference

    Väckelse, opposition, identitet. Omvändelser hos författaren Astrid Forsberg

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    Malin Gunnarsson, MA at the Department of Humanities, Comparative Literature, Mid Sweden University Revival, Opposition, Identity: Conversions in Astrid Forsberg’s Novels (Väckelse, opposition, identitet. Omvändelser hos författaren Astrid Forsberg) This essay explores the work of the Swedish author Astrid Forsberg. It focuses on the theme of conversion, which recurs in all ten of her novels. The books were written between 1925 and 1965. Forsberg was born in Bergsjö in 1898. She grew up in a Baptist home and later converted to Catholicism. Before her debut as a fiction writer she was a teacher and a journalist. She also wrote drama and poetry. Forsberg died in Stockholm in 1966. This essay identifies three separate aspects of the conversion theme: Christian, social and individual. The Christian revival conversion functions as a standard model. It is expressed both as a love for Christ and as a life lived in conscientiousness. The social conversion is expressed through opposition, love and Bildung. Finally, the individual conversion is the character’s struggle for a genuine self-image. This essay identifies a shift in Forsberg’s work, from identity creation in a Christian context, to a corresponding identity creation that is secular and individualistic. Subsequently there is a move back, where the characters turn to God again, but from a more individualistic vantage point. These shifts between different ways of identitying creation in Forsberg’s novels have a parallel in the differences between a philosophical and a rhetorical ideal of education, as reflected in the German word Bildung

    Väckelse, opposition, identitet [Elektronisk resurs] : Omvändelser hos författaren Astrid Forsberg

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    Malin Gunnarsson, MA at the Department of Humanities, Comparative Literature, Mid Sweden UniversityRevival, Opposition, Identity: Conversions in Astrid Forsberg’s Novels (Väckelse, opposition, identitet. Omvändelser hos författaren Astrid Forsberg)This essay explores the work of the Swedish author Astrid Forsberg. It focuses on the theme of conversion, which recurs in all ten of her novels. The books were written between 1925 and 1965. Forsberg was born in Bergsjö in 1898. She grew up in a Baptist home and later converted to Catholicism. Before her debut as a fiction writer she was a teacher and a journalist. She also wrote drama and poetry. Forsberg died in Stockholm in 1966.This essay identifies three separate aspects of the conversion theme: Christian, social and individual. The Christian revival conversion functions as a standard model. It is expressed both as a love for Christ and as a life lived in conscientiousness. The social conversion is expressed through opposition, love and Bildung. Finally, the individual conversion is the character’s struggle for a genuine self-image. This essay identifies a shift in Forsberg’s work, from identity creation in a Christian context, to a corresponding identity creation that is secular and individualistic. Subsequently there is a move back, where the characters turn to God again, but from a more individualistic vantage point. These shifts between different ways of identitying creation in Forsberg’s novels have a parallel in the differences between a philosophical and a rhetorical ideal of education, as reflected in the German word Bildung.</p
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