1,720,971 research outputs found
Incidence of hemagglutination activity among pathogenic and non pathogenic Bacteroides fragilis strains and role of capsule and pili in HA and adherence.
No full textInproved susceptibilities to cinoxacin and other antimicrobial agents of some Providencia species re-identified on the basis of polyhdric alcohols fermentation
No full textIn vitro and in vivo microbiological evaluations of cefoperazone
No full textEvaluations of minimum inhibitory concentrations MICs) were carried out with cefoperazone on 35 gram-positive, 60 gram-negative, and 64 anaerobic strains. Results were compared to those obtained with cefuroxime, cefoxitin, cephaloridine, cefazolin, cephalexin and (for the anaerobic bacteria only) cephalothin. In vitro activity of cefoperazone was excellent against strains of Streptococcus faecalis (MICs between 6.25 and 12.5 μg/ml) and Staphylococcus aureus (100% of the tested strains were inhibited by ≤ 12.5 μg/ml). Cefoperazone activity against gram-negative strains was superior to that of all the other cephalosporins tested. It is noteworthy that all of the Proteus species and Pseudomonas aeruginosa strains were inhibited by ≤ 50 μg/ml cefoperazone, a level readily achievable in serum with normal dosages. All Escherichia coli were inhibited by ≤ 1.56 μg/ml. In vitro activity of cefoperazone was extremely high against anaerobic bacteria: 100% of the strains tested were susceptible at ≤ 1.56 μg/ml. The PD50 values in experimental infections in mice confirmed the high in vitro activity of cefoperazone, with lower doses required for protection than for the other cephalosporins tested. This may be due to the favorable pharmacokinetics of cefoperazone. The stability of cefoperazone in the presence of beta-lactamase was also confirmed
Determinatins of tissue levels of cefatrizine in blood, longs and bronchi.
No full textA study was carried out in 12 patients, divided into two groups of 6, to determine tissue levels of cefatrizine in lung (group I) and bronchial secretions (group II) following a single oral dose of 500 mg. In group I, specimens of blood and lung tissue were collected after 2 h from one subgroup of 3 patients and after 3 h from the other subgroup of 3. Average levels were 8.5 and 7.0 mcg/ml for blood and 1.2 and 1.4 mcg/ml for lung tissue respectively. In group II blood and bronchial secretion concentrations were evaluated at the 2nd, 3rd and 6th hours from administration. Average values were 9.1 and 7.7 mcg/ml in blood at 2h and 3h respectively, whereas the average bronchial secretion concentration at the 3rd hour was 10.4 mcg/ml in the first subgroup. In the second subgroup the mean level in blood collected at the 2nd hour was 8.9 mcg/ml, and 2.5 and 4.1 mcg/ml respectively in blood and bronchial secretions at the 6th hour. Cefatrizine levels in bronchial secretions were higher than those in blood at both the 3rd and the 6th hour from administration: this kinetic peculiarity of the drug will doubtless play an important role in the therapeutic efficacy of cefatrizine
In vitro activity of ciprofloxacin against aerobic bacteria isolated in a southern European hospital
No full textThe activity of ciprofloxacin was evaluated against 1,204 isolates freshly isolated in Southern Europe, including 193 isolates of 10 species never studied before. Ciprofloxacin proved more active than other quinolones and very active in absolute terms against the 10 new species and showed against the other species an activity close to that reported for isolates from other geographic areas
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Comparative in vitro activity of cefodizime and other antibiotics against pathogens recently isoated in Italy.
No full textDOUBLE SUGAR-TYROSINE MEDIUM IMPROVES O-1 PHAGE SALMONELLA SCREENING
No full textA modification of the procedure for O-1 phage Salmonella screening is presented. The novel method is based on the use of two media, i.e., a new medium (double sugar-tyrosine [DST]), which permits the combination of adonitol and sucrose fermentation and tyrosine clearing tests, and the previously described o-nitrophenyl-beta-D-galactopyranoside urease indole medium. In comparative trials, the new procedure and the conventional one were used to screen for Salmonella isolates from 553 lactose-negative strains of members of the family Enterobacteriaceae. The O-1 phage test, performed on DST medium, recognized the same number of phage-susceptible Salmonella strains as did the standardized method; however, it permitted the correct identification of a greater number of phage-resistant strains for discard (95.6 versus 85.3%). In particular, DST medium presented a higher efficacy than triple sugar iron agar (which is the corresponding medium in the reference procedure) in correctly identifying phage-negative cultures for discard (69.1 versus 28.5%)
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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